Currently, vehicle to vehicle communication is an important application and thrust area of research. In this paper the author highlighted the workings, executions, implementations and the application of the Internet of Things (IoT) in transport management and vehicle to vehicle communication systems. The main advantage of this Industry 4.0 based IoT technology is that it helps us to reduce road traffic and accidents. The limitations of GPS like accuracy, precision, effective analysis, etc. has led to the evolution of Mobile based V2V communication which is more effective, error proof, result oriented and smart. For proper analysis of traffic vehicle to vehicle communication is established. Random Data from vehicles taken by numerous sensors. Any car coming in its variety could effortlessly share the data by either of two cars nearby. With the help of vehicle to vehicle communication we can provide a path of emergency vehicles to reach the destination quickly. Based on the V2V application, Red and Green signals can be marked on the path as per traffic density and the emergency vehicle can take the shortest, fastest and low density route. Similar such examples are elaborated in the current research manuscript that will help the researcher in effectively finding the research gap for further advancement, analysis, innovation and optimization.
Brushites are the most commonly found phosphate stones in the kidneys, ureters and urinary bladder. The study was conducted to observe the possible growth patterns of brushite crystals in the gel for 14 days. The crystal formation was observed as a bullet, needle, platy, columnar shaped and their aggregates. Magono and Lee's meteorological classification further explained these shapes. Besides the morphology, the average size, number and weight of crystals were also observed on the 7th and 14th days. Energy Dispersive X-ray, Fourier Transform Infra Red spectroscopy and Scanning Electron Microscopy were used to characterize the crystals. These results can help to determine the promotion, modulation and inhibition of the crystals, which will be helpful in evaluating the risk factors and prophylactic management of brushite-type urinary stones.
Recently, novel materials like gas-sensing metal oxides, mixed metal oxides, and modified mixed metal oxides have attracted great attention owing to their key roles in monitoring environmental pollution, security in hospitals, homes, and public places, and hazardous emissions from industries and automobile exhaust. Initially, the mechanochemical (MCh) method was employed for the synthesis of the CuMnO3 catalyst and then the modification of CuMnO3 through the hydrothermal route. These synthesized catalysts were characterized by Ultraviolet Violet-Diffused Reflectance (UV-DRS) spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscopy (SEM). The average particle size obtained for 3 % Fe/CuMnO3 was found to be 14–28 nm. The present work proclaimed that among all the synthesized 1,3,5 % Fe/CuMnO3 materials, the 3 % Fe modified CuMnO3 material shows significant gas sensing properties towards highly toxic H2S gas released from sewage plants, oil, and natural gas industries, among NH3, CO2, H2S, H2, CO2 and Cl2 with moderate temperature requirements and excellent selectivity.
This dissertation aimed to critically investigate how UK manufacturing companies can employ 3PL services to enhance business profitability. A simple, cross-sectional sequential mixed methods research methodology was implemented with the qualitative phase being used to explain the findings of the quantitative phase, which was performed first. Data for the quantitative period were collected using an online questionnaire that was designed and administered through a Google survey (N= 416). At the same time, semi-structured interviews were performed via Zoom calls with senior executives and managers of UK manufacturing firms (N= 5). Descriptive statistics, a one-sample t-test, and stepwise regression were used for quantitative data analysis using SPSS while manual analysis of interview data was performed in Microsoft Excel. The results showed that transportation and fleet management were the services that UK manufacturing companies outsourced to the most significant extent while clearing and forward and inventory management were the services that were outsourced to the lowest degree. The reasons behind this trend included the level of risk involved in outsourcing a particular service, availability of 3PL providers offering the outsourcing service, and the cost involved. In terms of feasibility, all items were scored highly, although increased operational flexibility and significant reduction of operational costs ranked highest. Finally, the stepwise regression test revealed four statistically significant models with an overall prediction power of 20.1% on business profitability. The statistically significant predictor variables were a reduction of operational costs, increased operational flexibility, reduced fixed asset costs, and the gaining of external resources from 3PL service providers.
Oral cavity harbors a complex network of microorganisms which are in steady state of equilibrium with another microflora. Surgical removal of third molar is a very common procedure in oral surgery and suturing of surgical site is a crucial component determining success of wound healing. These suture materials sometime act a nidus of infection because of potential adherence of bacteria to its rough surfaces which may lead to surgical site infection. AIM- The aim of this study was to compare bacterial load on normal silk suture over antibacterial suture following third molar removal in 50 healthy individuals free of any systemic and local pathology. MATERIALS AND METHODS – A microbiological analysis using culture sensitivity test of distal most suture was evaluated after 7 days of procedure. RESULT - In relation to the colony count silk group showed higher number of colonization with a median of 80,000 cfu/ml. Relatively on the other side, antibacterial showed significant decrease in number of colonization with a median of 11,000 cfu/ml (p value < 0.0005). CONCLUSION – Antibacterial sutures group showed statistically significant reduction in bacterial count and can be possible alternative in patients who are unable to maintain good oral hygiene.
Gingivitis, a reversible inflammation of the gums leads to an advancement to periodontitis, a more severe and often irreversible stage characterized by the destruction of connective tissue and bone, potentially leading to tooth loss. This study was designed to develop and evaluate muco-adhesive buccal films containing metronidazole for localized treatment of periodontal disease, aiming to reduce systemic side effects and improve therapeutic efficacy. Thin films were prepared using chitosan as the primary polymer, combined with various copolymers (HPMC, MC, EC, PVP, HPC, and Carbopol) via the solvent casting technique. Thirteen formulations (F1-F13) were investigated for their ability to control the in vitro drug release, surface pH, folding endurance, drug content uniformity, and muco-adhesion, in addition to studying drug release kinetics. Formulations F12 (60.0% HPMC, 20.0% chitosan) and F13 (20.0% HPMC, 60.0% chitosan) showed optimal surface pH (≈6.7-7.0) with high muco-adhesion characteristics (49-51 Mn/m). Sustaining or expediting the drug release rate was manipulated by tailoring the polymer composition within the studied formulations. Examining drug release data has shown that the release kinetics followed the Korsmeyer-Peppas model, indicating diffusion and polymer relaxation mechanisms. The study demonstrates that polymer selection, in addition to the chosen ratio allows customization of release kinetics, Formulation F9 (20.0% HPC, 60.0% Chitosan) was proven to have the ability to provide the most sustained release characteristics. These findings support the potential of chitosan-based muco-adhesive films as effective localized delivery systems for metronidazole in periodontal therapy.
Mediterranean journal of pharmacy and pharmaceutical sciences
A burning sensation on eating spicy foods purportedly supports the role of capsaicin, an active component of chili peppers, in the etiology of oral submucous fibrosis (OSF). Although the mast cell mediators and activated P2X receptors induce a constant burning sensation through an ATP-dependent mechanism, it is the activation of the transient receptor potential vanilloid 1 (TRPV-1) receptor by capsaicin that aggravates it. The molecular basis for the burning pain in OSF is thus attributable to the activation of TRPV1. There is overwhelming evidence that confirms capsaicin has more of a protective role in attenuating fibrosis and is potentially therapeutic in reversing conditions linked to collagen accumulation. The activation of TRPV-1 by capsaicin increases intracellular calcium ([Ca2+]i), upregulates AMP-activated protein kinase (AMPK) and Sirtuin-1 (SIRT-1), to enrich endothelium-dependent vasodilation via endothelial nitric oxide synthase (eNOS). The induction of vasodilation induces antifibrotic effects by alleviating hypoxia. The antifibrotic effects of capsaicin are mediated through the upregulation of antioxidant enzymes, downregulation of inflammatory genes and suppression of new collagen fibril formation. Capsaicin also demonstrates an anticarcinogenic effect by upregulating the cytotoxic T cells and downregulating regulatory T cells through the inhibition of angiogenesis and promotion of apoptosis. Judicious administration of capsaicin with an appropriate delivery mechanism may have therapeutic benefits in reducing pain sensation, rendering antifibrotic effects, and preventing the malignant transformation of OSF. This paper provides an overview of the molecular basis of capsaicin and its therapeutic application as an antifibrotic and anticarcinogenic agent for the treatment of OSF
The study of diabetes is not only limited to particular symptoms, but it is consequently affects the pathological and functional changes in the metabolic pathways of human body system. In those symptomatic diseases various drugs are used to treat the diabetes such as biosimilar therapy including use of insulin and insulin analogues, oral hypoglycaemic agents and various other complementary medicines. In understanding of suggested potential antidiabetic, effect of M. charaantia Linn. on fasting blood sugar levels and its biochemical analysis in alloxan- induced diabetic rats were investigated. The extracts of M. charaantia Linn. Produced a significant antidiabetic activity at normal dose levels of their lethal doses. A comparison between the action of reduction in blood glucose level in different dose forms of M. charantia extract and Std. drug were seen. An oral glucose tolerance or oral tolerance test were performed with the use of glucose strip Accu-check meter. The different extract viz. ethanol extract + water, petroleum ether + Isopropyl alcohol extract were used for further dosing purpose. The ethanol + water extract were showed significant (P<0.001) antidiabetic activity. In alloxan induced rat model blood glucose level were as, 214.5±5 mg/dLfor std.drug and 216.5±5 mg/dL in comparison with diabetic control 225.5±5 mg/dL. An ANOVA was used for the statistical analysis and p-values less than 0.01 compared to normal group and 0.05 compared to diabetic control group were considered statistically significant. The extract of M.charantia Linn. from seed at the dose of 250 mg/kg, significantly shows the better result in reduction of blood glucose level as compared to the concentration of 500 mg/kg. The increased level of glucose due to the damage of pancreas showed regeneration of pancreatic enzymes by extract of M. charaantia Linn. Which were damaged by alloxan treatment. These solvent extract also balance the body weight loss in diabetic rat, hence the present extract shows the potential to act as antidiabetic drug.
Dans notre système éducatif, l’accès à la formation pédagogique pour l’enseignement primaire est accessible aux personnes dotées du certificat de l’école primaire. Or, le système éducatif les plus performants organisent un dis- positif de pré-sélection afin de former les meilleurs pour assurer un enseigne- ment de qualité. Le recours à la théorie des intelligences multiples, est salutaire pour le recrutement des futurs enseignants dans notre système éducatif. A partir de cette théorie, la formation initiale des enseignants et leurs recrutements sont spécifiquement bordés de trois axes à savoir : interpersonnel, linguistique et lo- gique/mathématique, pourquoi mettre de côté les autres formes d’intelligences ? Or l’enseignant du primaire doit bénéficier aujourd’hui d’une formation totale.
Tidal and riverine flows are viable energy sources for consistent energy production. Installing and operating marine hydrokinetic (MHK) turbines requires assessing any potential impact of debris accumulation on turbine performance and sediment transport. More specifically, MHK devices may alter the natural sediment transport processes and cause debris accumulation, disrupting the natural sediment dynamic. In turn, these processes could affect the turbine’s performance. We carried out a series of large-eddy simulations coupled with bed morphodynamics, introducing various debris loads lodged on the upstream face of a utility-scale turbine tower. The objective is to systematically investigate the impact of debris accumulation on the performance and hydro-and morpho-dynamics interactions of the horizontal-axis MHK turbine under rigid and mobile bed conditions. To that end, we (1) employed the actuator line and surface methods for modeling turbine blades and the nacelle, respectively,(2) directly resolved individual logs, and (3) solved the Exner equation to obtain the instantaneous bed deformation of the mobile bed. Our analysis revealed that while the spinning rotor amplifies scour around the pile, debris accumulation modifies the sediment dynamics of the system. Also, it found that morphodynamic processes accelerate the wake recovery, slightly enhancing the turbine's performance.
Higher Education has an important role in the task of rebuilding a nation and it pavCes the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution, so on and so forth, taking human civilization to new heights. At the start of 21st century, we gave a lot of importance given to higher education. Every country realized the value of higher education and the benefits that accrue from it. “The social demands for higher education continue to increase. The inabilities of the state to support this growing demand result in new financing arrangements for higher education. The recent reforms in this area could be broadly divided into two categories: the privatization of public institutions and the establishment of private institutions of higher education. Privatization implies the application of market principles in the operation of public institutions, while ownership rests within the public domain. Promotion of the private sector implies the growth and expansion of the non-state sector in higher education, and very often this sector does not rely on state funding for its growth and expansion. Both of these measures have paved the way for market operations in higher education
Argostemma quarantena, a new rubiaceous species from Vagamon Hills of southern Western Ghats, India is described and illustrated here. The species shows similarities with two south Indian endemics, A. anupama and A. courtallense, but differs in many qualitative attributes. The present status of genus Argostemma in India is briefly discussed. An artificial key for the identification of Argostemma in Western Ghats is also provided.
A zoonotic disease is an infectious disease caused by pathogens such as bacteria, virus, rickettsia, fungi, parasite or prion that has been transmitted from an animal, especially a vertebrate to human beings. Usually, the first infected human transmits the infectious agent to other humans very rapidly; it is one of the important concerns of zoonoses. The World Health Organization (WHO) currently list the Emerging infectious diseases (EID) of epidemic issues in their research and development blueprint as COVID-19 (Corona viruses), Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS), Ebola and Marburg viruses (Filovirus), Crimean Congo haemorrhagic fever (Nairo virus), Lassa Fever (Lassa virus), Nipah (Henipa virus ), Rift Valley fever (Phlebo virus) and Zika (Flavi virus). Due to the deadly pandemics facing by the globe, it is essential to understand the way of transmission of emerging viruses, its mode of infection and important measures to eliminate or control them from the world is essential. However, mankind overcomes so many deadly viruses with the help of scientific knowledge, through vaccination, new therapies, drugs etc. Nowadays, viral zoonoses like rabies (Lyssa virus) are 100% preventable through vaccination and medication even though, humans face lots of new threats especially emerging zoonosis diseases like Covid19. This review summarized the major zoonotic viruses affecting human beings, their source, pathogenicity and its important ways to overcome the transmission of microbes from animal to humankind.
Les études sur la langue française la présente souvent dans des situations où elle est en contact avec les langues africaines. Elle co-apparait avec les langues africaines dans les discours romanesques. Cette co-apparition n’est pas sans conséquences pour les deux langues en contact. Certains linguistes, surtout les sociolinguistes et les didacticiens, parlent d’insécurité linguistique. Ils la lient à toutes les situations linguistiques où deux langues entrent en contact. Ngamassu (2007, p.94) dit dans ce sens que « toute situation de contact des langues est source d’insécurité linguistique, car aucun locuteur/scripteur ne peut maîtriser toutes les variétés ou niveaux d’une langue ». Cette affirmation restreint l’insécurité au locuteur ou au scripteur. Les linguistes ignorent souvent l’impact négatif du contact des langues et s’intéressent à ses conséquences positives. Cet article a porté sur les manifestations de l’insécurité linguistique dans la prose romanesque de Kourouma et Badaman. Il a permis de voir que l’usage des langues maternelles dans le français constituait une menace de disparition et d’abâtardissement de la langue française.
PKN Subject is on one of lesson implemented on SD, SMP and SMA to apply student characters and to form the student to understand and love home land also understand global life. The research background of the low student achievement on study still using lecture method, giving assignments, answer and guestion on PKN subject. The purposes of this research: 1.how student achievement on PKN subject before using word sguare model. 2. How student achievement on PKN subject after using calassroom action rescarch with quantitative approach. The sample is the students of class III MIS NU 2 Pontianak.in order to get the data, researcher using observation shett, measurement technique and documentation study.The result concluded: 1.the student achievement before using word square model the average is 53 ( good category ) with KKM > 70 as 5 or 25% and students with KKM < 70 as 15 students or 75%. 2. The student achievement after using word square on cycle 1 is 68,5 ( Better category) with KKM 55%. On the other hands, cycle 11 is 82,5 (Great category ) with KKM 90%. Mata pelajaran PKn salah satu pelajaran yang diterapkan mulai dari SD, SMP dan SMA dengan membekali karakter dan membentuk peserta didik cinta tanah air dan paham dalam kehidupan yang serba global. Rumusan penelitian ini; 1) Bagaimanan hasil belajar siswa pada mata pelajaran pendidikan kewarganegaraan sebelum menggunakan model pembelajaran word square kelas 3 MIS NU 2 Pontianak. 2) Bagaimana hasil belajar siswa pada mata pelajaran pendidikan kewarganegaraan setelah menggunakan model pembelajaran word square kelas 3 MIS NU 2 Pontianak. Metode dan jenis penelitian ini menggunakan jenis penelitian tindakan kelas dengan pendekatan kuantitatif.Subjek penelitian ini adalah siswa kelas III MIS NU 2 Pontianak. Untuk mendapatkan data peneliti menggunakan lembar observasi, teknik pengukuran dan studi dokumentasi. Hasil dari penelitian ini yaitu: 1) Hasil belajar siswa pada Mata Pelajaran PKn sebelum menggunakan model pembelajaran Word Square diperoleh nilai rata-rata sebesar 53 (kategori cukup) dengan siswa yang tuntas mencapai nilai KKM ? 70 sebanyak 5 atau 25% dan siswa yang tidak tuntas dengan nilai KKM ? 70 sebanyak 15 siswa atau 75%. 2) Hasil belajar siswa pada Mata Pelajaran PKn setelah menggunakan model pembelajaran Word Square pada siklus I sebesar 68,5 (kategori baik) dan siswa yang mencapai KKM sebesar 55%. Sedangkan pada siklus II sebesar 82,5 (kategori sangat baik) dan siswa yang mencapai KKM sebesar 90.
Crude methanol extracts of the leaves of Adenanthera pavonina L., Peltoforum roxburghii L, Prosopis cineraria L., and Prosopis juliflora DC., were evaluated for anti-emetic activity. Emesis was induced by the oral administration of copper sulphate 50mg/kg body weight to male chicks of four days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. All extracts (150 mg / kg body weight orally) showed anti-emetic activity when compared with standard drug Chlorpromazine at the same dose. Among all the extracts, Prosopis juliflora showed the highest (73.64%) and Adenanthera pavonina showed the lowest (50.17%) anti-emetic activity
Abstract Indian telecom industry has started growing rapidly since 1990 because of market liberalization. It has become one of the fastest growing telecom markets since then. Operating performance of a firm is depending upon certain key financial factors viz., turnover, profit, asset utilization etc. and the variables which are found in profit and loss account and balance sheet of a firm have a direct or indirect relation with each other. Financial performance of the firms can be analyzed by establishing a close relationship between the variables, in terms of liquidity, profitability, viability and sustainability. By establishing a close relationship between the variables, a firm can analyze its financial performance in terms of liquidity, profitability, viability and sustainability. Ratios and the statistical tool of ANOVA are normally used to identify the financial health of the firms and financial performances of the firms are measured accordingly. So the present study concentrates on empirical approach towards measuring deals with financial performance of the telecommunication companies.
The learning process in the new normal is currently still undergoing a process of adaptation. Where the learning is still limited face-to-face and some others are brave. Process adaptation. This learning requires an NHT learning technique that makes it easier for class II students to understand the concept of social studies learning in the natural and artificial environment as a whole and is able to increase their motivation in learning. The research method uses a quantitative design using a non-equivalent control group design. The variables of this study consisted of independent variables and dependent variables. The population of this study were all second grade students at Anak Saleh Elementary School, while the samples were second grade students who carried out the bold learning process and second grade students who carried out offline learning processes. The data collection used in this study included interviews, questionnaires and observations. The data analysis technique is validity test and reliability test. Analysis of the data used through data coding, data transfer to a computer using prerequisite tests and hypothesis testing. The results of the research show: 1) the level of understanding of the social studies concept of class II students who study with the Numbered Head Together (NHT) learning technique is better than conventional learning techniques of 0.429 (results from the t-test) and 2) the level of motivation to learn social studies of class students II with Numbered Head Together (NHT) learning technique of 0.733 is better than conventional learning which is only 0.704. Surely this is greater than rtable = 0.361.
The choice of the study design is a major determinant of scientific quality and clinical value of a research study. To select an appropriate study design is a perplex task for novice as well as veterans in research. AYUSH systems of medicines have evidence database showing the effectiveness in a wide range of clinical conditions, yet improving the quality of trials by well- designed studies is indispensable to demonstrate widespread utility on more scientific grounds. This article describes the structured classification of research designs done on the basis of a selective literature search concerning medical research. The study design and type that can best answer the particular research question at hand must be determined not only on a scientific basis, but also in view of the available resources, ethical issues and practical feasibility of study.
Recently, wireless sensor networks (WSNs) have been deployed for a wide variety of applications, including military sensing and tracking, patient status monitoring, traffic flow monitoring, where sensory devices often move between different locations. Securing data and communications requires suitable encryption key protocols. In this paper, we propose a certificateless-effective key management (CL-EKM) protocol for secure communication in dynamic WSNs characterized by node mobility. The CL-EKM supports efficient key updates when a node leaves or joins a cluster and ensures forward and backward key secrecy. The protocol also supports efficient key revocation for compromised nodes and minimizes the impact of a node compromise on the security of other communication links. A security analysis of our scheme shows that our protocol is effective in defending against various attacks.We implement CL-EKM in Contiki OS and simulate it using Cooja simulator to assess its time, energy, communication, and memory performance.