As we aware diabetes is not only one kind of symptomatic disease but its occurrence spread through the various metabolic channels and hence raises other disorders. The prolonged symptoms of diabetes also cause the complications of eyesight, Night blindness, kidney failure, and other autoimmuno dysfunction including sexual dysfunction. In those symptomatic diseases various drugs are used to treat the diabetes such as biosimilar therapy including use of insulin and insulin analogues, oral hypoglycaemic agents and various other complementary medicines. As herbal remedies i.e. M charantia Linn. (Bitter Gourd) are commonly known as fruit vegetables. The Leaves, Seeds, Roots, Fruits and the stem part of the plants are medicinally used in different diseases. It is most effectively used to treat the acidic condition of gastrointestinal tract. M.charantia is also called the oxygen radical scavenger, which takes part into metabolic pathway. Due to the oxygen radical scavenging activity of GSH it directly expedites the ROS neutralization and the repair of ROS-induced damage which is important to neutralize the acidic condition of gastrointestinal tract.The present investigation was carried out to study the characterization of present antidiabetic compound having different solvent extract of M.charantia in various solvent system. The overall conclusion suggested that the extracted compound shows the antidiabetic and diuretic properties. The total unknown protein concentration was 21.01 µg/mL which is similar with standard antidiabetic drug and the slope consists of 0.0314 with the line of intercept 0.081, which has been elaborated in results and conclusion.

Dr. wahul umesh b

A new feature generates customer delight by using modern computer vision techniques to drive new search paradigms through visual discovery.

Senthilkumar gopal

Covid 19, the pandemic originated in the Chinese city of Wuhan, had the entire world conquered. The structure and transmission of the causative organism, Coronavirus is well studied. Remdesivir, the product of Gilead pharmaceuticals, was effective against many viral infections, including Ebola and SARS. It comes under the category of nucleoside prodrug and has given promising results in the early trials against SARS COV 19. In depth, research is taking place at a rapid pace, so that Remdesivir will be available to the therapeutic community as an effective remedy for the pandemic caused by SARS COV2. If this meets success, the darkest era in the modern history of mankind may become a memory in the near future.

Vinod b

This article investigates the integration of Artificial Intelligence (AI) with Electronic Health Records (EHR), exploring the transformative impact of this synergy on healthcare informatics. Through an in-depth analysis of recent advancements, practical implementations, and ethical considerations, the paper illuminates how AI is enhancing the efficiency, accuracy, and insights derived from EHR, ultimately contributing to improved patient care and clinical decision-making.

Dhruvitkumar talati

This study explores the influence of education, length of service, professionalism, and ethics on the professional values of public relations practitioners in Malaysia. A total of 427 questionnaires were distributed to public relations practitioners in Malaysia, and 322 questionnaires were returned. The study included 61% female respondents, and 39% male respondents. The study analyzed and identified the influence of professionalism and ethics on professional values of public relations practitioners. Additionally, the study examined whether education and experience influence professional values through professionalism, and code of ethics. Six hypotheses were tested to answer the research questions. The results from this study fully supported the hypotheses indicating that professionalism and ethics had an influence on professional values of public relations practitioners. The results also showed that education influenced both professionalism and ethics, and length of service influenced both professionalism and ethical practice.

Mohammed fadel arandas

Management information systems are computer systems within an organisation that incorporate both hardware and software operations. It involves using business processes, people, and technology to collect, record, process, and store essential data that is significant to decision-making processes (Hartanto and Asmuni, 2017, 11). Management information systems are also used to coordinate, analyse, control, and visualise crucial organisational information. The ultimate goal of using MIS within the corporate environment is to increase value creation and profit earnings for businesses.

Zamzam abdelazim

Background Type 2 diabetes and obesity are serious public health concerns globally and a growing burden in Africa. Both conditions have serious repercussions on health when they co-occur, yet the extent of their co-occurrence in Africa remains unknown. Therefore, this review aimed to identify the prevalence and associated factors of overweight and obesity among persons with type 2 diabetes in Africa. Method A systematic search was conducted on PubMed, MEDLINE, Embase, African Index Medicus (AIM), and African Journals Online (AJOL) for observational studies that reported the prevalence of overweight and/or obesity among type 2 diabetes patients in Africa. The prevalence data from individual studies were aggregated through a random-effects meta-analysis. The I2 statistic was used to evaluate between-studies heterogeneity, while subgroup analysis and mixed-effects meta-regression were performed to identify sources of heterogeneity. We assessed publication bias using funnel plots and Egger’s test. This review adhered to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Results Of 1753 records retrieved, 80 articles were eligible for this review, with 74 cross-sectional studies included in the meta-analysis. The pooled prevalence of overweight and obesity was 35.6% and 25.6% respectively, while the overall prevalence of both overweight and obesity was 61.4%. Also, the pooled prevalence of both overweight and obesity across the five geographical areas in Africa ranged from 56.9% in East Africa to 88.5% in Southern Africa. Nineteen factors were significantly associated with overweight and obesity among patients with type 2 diabetes. Conclusion The high prevalence of overweight and obesity among patients with type 2 diabetes is a significant public health concern that transcends geographical boundaries within Africa. The findings from this review highlight the need for innovative weight management interventions that are tailored to the cultural context of the African setting

Emmanuel ekpor

Malwares are one of the most dangerous security threats in today’s world of fast growing technology. Now, it is not impossible to remotely lock down a system’s files for ransoms even when it is located overseas. This threat was accelerated when the world was introduced to cryptocurrency (for e.g., Bitcoins). It allowed the attackers to hide their tracks more efficiently. From a simple idea of testing the efficiency of a computer system to the most critical and sophisticated cyber-attack, malwares has evolved over the years and appeared time to time. Even with the smartest technologies today where we are trying to include Machine learning and Deep learning to every field of our life, the attackers are already developing more sophisticated malwares using the same Machine learning and Deep learning techniques. This raises the question on the security of the cyber-world and how we are able to protect it. In this work, we are presenting an analysis on a recent and most critical Windows malware called “LockerGoga”. Both static and dynamic analyses are performed on the malware to understand the behavior and characteristics of the malware.

Dr. chandrashekhar uppin

On January 2021, cases affected by coronavirus epidemic are constantly increasing, Libyan Ministry of Health provides the vaccine to the people those who are most at risk. The purpose of this study was to assess and verify the adverse effects of the first dose of the AstraZeneca COVID-19 vaccine. The study conducted at the Aljmail city, west region of Libya. The study was cross-sectional study during the period of August 31st and November 5th, 2021. The method involved 133 adult Libyan participants of both gender ageing more than 18 years old. The preliminary data were 54.0% who developed post-vaccination symptoms. The participant's aged 60 years and more with chronic diseases were more likely to have adverse effects after receiving the first dose of vaccine. In conclusion, AstraZeneca vaccine was good and effective but this study indicates a need for a large and long period study to confirm the safety of the vaccine use in the adult people.

Mediterranean journal of pharmacy and pharmaceutical sciences

Mutual fund investment specifically in India and particularly in western Maharashtra is a very challenging aspect. This paper aims to study various factors influencing the investor’s choice of mutual fund, criteria for selecting particular scheme, previous performance of Mutual fund asset Management Company and services provided by them. Similarly Investor education and awareness. To have the competitive advantage proactive steps taken by the Asset management companies would be beneficial like proper financial planning guidelines, providing information pertaining to Net asset value, benchmark indices, analysing purchase decision involvement of the investors and very importantly understanding the risk averse behaviour of the investors and adequate and reliable information about the scheme.Understanding investor behaviour, specifically information search and Processing behaviour of mutual fund schemes is instrumental for effective marketing. Perhaps very few researchers have focused on investor behavioural finance. It is complex set of understanding pertaining to investor psychology; various parameters guiding principles and risk averse capability of the investor dynamically guide the behaviour. Mutual fund companies while promoting the products and marketing need to consider these several influencing parameters so as to effectively cater to the needs of the investor which would truly win the customers and enhance customer confidence and trust.Risk aversion behaviour is also the key to understand the investor risk appetite behaviour in terms of conservative or aggressive investor measuring various demographic and psychographic metrics that play a crucial role to predict and understand the likely behaviour.

Nitin mali

To test and popularize the Krishi Vigyan Kendra, Barmer-II, Gudamalami, Rajasthan recommended Enhance the Productivity of Ridge gourd (Luffa acutangula L.) Cultivation in Net Trellis System in Barmer District of Rajasthan, On Farm Trials (OFT’s) were conducted during the kharif season of 2019 and 2020 in farmers participatory mode at three locations in Barmer District of Rajasthan. The experiment consisted of two treatments viz., recommended practice (Net trellis system) and farmers practice (Furrow). Net trellis system had significant increase number of picking (13), fruit length (43.33 cm) and fruit weight (210 g) as compared to farmer’s practice (07, 22.67 cm and 101.5 g) during both the year as well as pooled data. The two year average fruit yields of net trellis system have shown doubled production over farmers practice method. Net trellis system was recorded increase yield for 73.57% (138.06 t/ha) as compared to farmers practice (79.54 t/ha) during both the year as well as pooled data. Similarly, the net returns and B:C ratio also revealed that maximum under net trellis system during both the year as well as pooled data Rs 232790 per hectare and 3.36:1 as compared to farmers practice Rs 89913.5 per hectare and 2.30:1. Net trellis system had significant reduce the damage of pest and soil borne diseases and improve the quality of fruits

Dr. babu lal jat

The use of geo-morphometric variables to discriminate fish populations is one of the appropriate, effective and widely adopted approaches to study population dynamics. To determine intrinsic population variability in goldstripe ponyfish, Karalla daura sampled from Keti Bunder, Karachi Fish Harbour, Hawks Bay and Pasni along the coastal belt of Pakistan. Size frequency distribution based on normal distribution demonstrates that individuals of 13 cm total length were common in all groups. Some fifteen morphometric and six geometric variables were used to develop Principal Component Analysis (PCA) that revealed (76%, 13.9% and 9.8%) variation deduced from first three components. The population sampled from Karachi fish harbors showed significant taxonomic variability. An eigenvalue 7.251 and canonical correlation 0.937 among four groups was appraised from PCI whereas Wilks’ Lambda test of function λ = 0.27 was significant at P <0.05. The highest variance percentage was the most correlated among the groups defined by total length, girth, 2nd dorsal fin, pectoral fin rays, eye dia, snout to extended gill cover and head length parameters. PC-II accounted for 13.9% of the variance that are more correlated with standard length, snout to eye tip, eye tip to first dorsal fin, base of 1st dorsal fin, last fin ray to tip of caudal, anal fin ray to pelvic fin ray, chin to snout and pelvic fin to pectoral fin. PC-III showed 9.8% variance with fork length, total weight, anal fin rays, last anal fin ray to 1st dorsal fin, tip of caudal fin to last anal fin ray, last anal fin ray to 1st anal fin, first pelvic fin to chin, eye to chin, 1st dorsal fin to last anal fin ray and last dorsal ray to last anal fin ray. among the groups. Whereas PC-IV has 0.3 % variance denoted by total weight, tip caudal fin to last anal fin ray. The PCA displayed a clear discrimination by sampling site, especially specimen from Karachi fish harbor were distinct from other location. Keti Bandar specimen was not dispersing as much as by geographical discrimination. Overall, results revealed that different topographies and environmental conditions causing significant variation in populations of Karalla daura. Therefore, it is assumed that this species has ability to adopt different ecosystem for survival despite acquiring adverse impact on phenotypic characteristics.

Imtiaz kashani

The current study was designed to explore the antiemetic effect of the methanolic extract of Tithonia diversifolia (Hemsl.) A. Gray., leaves using chick emesis model to validate their folk use in G.I. disorders. Emesis was induced by the oral administration of copper sulfate 50mg/kg body weight to male chicks of four days of age. The antiemetic activity was determined by calculating the mean decrease in the number of retching compared to the control. Tithonia diversifolia leaves extract (150 mg/kg orally) showed a significant (p <0.05) antiemetic effect and was compared with the reference drug chlorpromazine.

Dr. salman ahmed

The main purpose of the research is to develop modern tools for insurance management in the global economic crisis, to make an objective assessment based on a critical analysis of existing ones, to identify situations that could lead to international economic, social and natural threats. It is made some recommendations for the development of insurance calculations for the republic of Uzbekistan. Methods: Methods for reforming modern calculation of insurance tariff are recommended by means of theories of probabilities, statistical and mathematical analysis, and foreign advanced countries practical types of summarizing. Findings: While making an analysis, it has found that modern tools for the insurance management of Uzbekistan are needed. We proved this by the results of the modern calculation of insurance in tables (1-6). For the development of the insurance market of Uzbekistan, it should be analyzed by means of penetration and density of insurance premiums, making the deepest calculation of risks of the economy of Uzbekistan, and using the main principals and formulas of the theory of probability. Conclusions: In the end, we can take some results, and give some recommendations such as using the tools of theories of probabilities can help us find the main risks of economy, its powers of influences of the market economy, statistical and mathematical analysis also add some practical, objective results for making under control of any types of insurance risks.

Ikboljon odashev mashrabjonovich

ABSTRACT Background: The coronavirus disease (COVID-19) infection rate and mortality among Nigerian health care workers appear to be on the increase. Aside from health workers, it has caused millions of infections and deaths worldwide. This study determined the level of knowledge, attitude, and practices of nursing and midwifery students towards COVID-19 in a North-Eastern Nigerian state. Methods: A total of 156 respondents were involved in this institutional-based cross-sectional study, conducted after the lockdown period. A total of 17 questions were used to assess the KAP with knowledge appraised with 12 questions, attitudes with 2 questions, and practices with 3 questions. Results: The majority of the students (53.80%) possessed a good level of knowledge regarding COVID-19, while 40.4% had fair knowledge regarding COVID-19 with only 5.80% having poor knowledge of COVID-19. The mean knowledge of COVID-19 in this study was 9.40±1.353 with an overall 78% correct answer rate. A vast majority of the respondent (82.7% and 98.1%) had strong confidence in Nigeria and believed that the pandemic will soon be over, respectively. Only a few avoided large gatherings of people (30.8%) with the vast majority reporting to have worn a mask when going out (84.6%) and washing their hands with running water and soap frequently as recommended (73.1%). In multiple logistic regression analyses, the COVID-19 knowledge score (OR: 0.39-0.40, 95%CI: 0.26 – 0.62, P<0.05) was significantly associated with a lower likelihood of negative preventive practices towards COVID-19. Conclusions: The participants in this study showed good knowledge, positive attitudes, and good practices toward COVID-19. There is still a need to strategize and implement periodic educational interventions and training on infection control practices among healthcare workers including students.

Hope inegbenosun

Community pharmacy has undergone a rapid expansion with various services moving away from the traditional supply function to other patient-focused services. Thus, the aim of this study is to examine consumer views and expectations toward the services provided in Libyan private community pharmacies, as well as customers' skepticism and their general satisfactions toward these services. The study is descriptive, cross-sectional survey and self-designed administered questionnaire. Study population comprised 0f adult patients or costumers who visited the community pharmacies. Out of the 600 questionnaires were personally handed, 462 of the distributed questionnaires were returned (response rate 77%). The majority of the participants reported that community pharmacy staff dealing with customers in polite ways (75%) and providing privacy and sufficient consideration (60%). Respondents agreed that the staff listens attentively and satisfied with encounter time by 60% and 50%, respectively. For provision of drug information as “how the drug work in the first-time use”, “customer experience of the side effects” and “their ability to using the prescribed medicine properly” were reported by 45%, 30% and 30%, correspondingly, while 60% of the respondents denied that staff provided the medication storage information. Regarding the customer skepticism toward community pharmacy services, 55% respondents agreed that services of community pharmacies tend to just concern on commercial aspects and 60% of respondents believed that services concern toward the business matter more likely than patient health. Interestingly, 85% of the respondents acknowledged the role of community pharmacy as indispensable healthcare setting. The availability of the pharmaceutical product and the cost of pharmacy products satisfied by 40% and 20% of the respondents, respectively. In conclusion, this study demonstrated low customer satisfaction with regard to community pharmacy services in the southern region of Libya. Community pharmacy staff should have an understanding of the codes of conduct and the ethical requirements for their practice of pharmacy profession.

Mediterranean journal of pharmacy and pharmaceutical sciences

An online travel agent is one of the platforms that has evolved throughout this digital era, including Tiket.com. Unfortunately, when the Covid-19 pandemic hit, online travel agents were affected the most. Now it is time for Tiket.com to evaluate its marketing strategies to increase the customers' purchase decisions. This research aims to analyze which strategies among Perceived Trust, E-Service Quality, Online Rating, and Online Review have the biggest influence on customer’s Purchase Decision on Tiket.com. This study is conducted from September to December 2022, using a quantitative method with purposive sampling by distributing an online questionnaire to 50 customers of Tiket.com. The data is analyzed for multiple regression analysis to find the influence of each independent variable on the dependent variable. Results show that E-Service Quality, Online Rating, and Online Review have a positive and significant influence on Purchase Decision while Perceived Trust has a positive but insignificant influence on Purchase Decision. Further, Online Rating is found to have the biggest influence on Purchase Decision. Thus, it is important for Tiket.com to pay attention to its Online Rating and Review, E-service Quality, and Perceived Trust.

L

Progress in treating young cancer has increased the survival rate of the disease in recent years. Their accomplishment has brought the survivors a new challenge: to cope with their ordeal's physical, psychological and social ramifications that may limit their social integration and growth. If a child is affected by cancer, people face a double vulnerability: they are young and they are unwell, exacerbated by the existence of a society that equates cancer with death and promotes its classification as a tabuous subject. The overarching purpose of the study is to look at social-health relationships and the need to integrate both points of view to foster the social development of survivors of paediatric cancer after therapy. A list of societal contexts, including families, schools, peer groups and associations, will be presented in this respect. The connections of the participants are transformed by overcoming oncological conditions in different circumstances, which lead to changes in their subjective well-being and the social pathways.

Dr. amarjeet singh

Diabetes is a global issue, the diabetes epidemic is expected to continue, and the burden of diabetes causes catastrophic expenditure for healthcare system. The current study aimed to determine the presentation, the clinical feature and cardio-vascular risk factors in patients with diabetes. A retrospective observational study had been conducted in out-patients department at Almustaqpal Almosherq Centre during September, 2013 till September, 2020, the total number of attended out-patients department were 1 024, 820 patients who were selected for this study. A special perform was completed for every patient, which included details about patient’s demographics, points in clinical history, relevant investigations and clinical examinations were recorded. The study reported that out of 820 patients, 66% (n = 538) was female and their age range was between 14 - 87 years with a mean age of 56.53 ± 13.49 years, 96% (n = 791) were clinically diagnosed as type II diabetes, 07% of the patients were diagnosed as pre-diabetes, the duration of diabetes ranged from newly diagnosed to more than 10 years, with 46% (n = 379) of the studied population were more than 10 years diabetes duration, 70% (581) were presented with classical symptoms of diabetes. Initial treatment for diabetes also different in the studied sample, were absent of anti-diabetic medications in 30% (n = 248) of the patients, they refused to start glucose lowering drugs, 34.6% (n = 284) of them have morbid obesity (body mass index is more than 40), 80% (n = 662) have high HBA1c (more than 8 g%), 40.3% (n = 240/596) were uncontrolled hypertension on anti-hypertension drugs, 95.6% (n = 682/713) were controlled on treatment of lipid lowering drugs. This study showing the presentation of diabetes were the common, type II diabetes, at age group between 41 - 66 years about 65%, female sex, with high body mass index, high glycated hemglobulin and uncontrolled hypertension. There is concern that diabetic patients were occurring at a high frequency in younger adults, where longer duration of illness could increase the risk of developing more complications in later life. The rate of coexist cardiovascular risk factors (hypertension, dyslipidaemia and obesity) in Libyan patients with diabetes is highlighted.

Mediterranean journal of pharmacy and pharmaceutical sciences

Background: Hospital acquired infections (HAIs) are infections that patients acquire while receiving treatments for other conditions. Studies have shown that stethoscopes and sphygmomanometers can act as potential sources of these infections in patients accessing treatment in healthcare facilities. This study aimed to increase awareness among health workers in Nigeria of the potentials of stethoscopes and sphygmomanometers to transmit HAIs. Methods: Moist swab sticks were used to collect samples from 38 randomly selected stethoscopes and sphygmomanometers from some departments of four district hospitals. Collected samples were cultured using standard microbiological techniques. In addition, self-designed questionnaire was used to assess the knowledge and practice of doctors and nurses on the roles of stethoscopes and sphygmomanometers in HAIs. Results: About 83.8% of the health workers demonstrated some awareness of the roles of stethoscopes and sphygmomanometers in HAIs. 42.5% cleaned their stethoscopes, while 5% their sphygmomanometers. Staphylococcus aureus, (65.9% of stethoscopes), proteus mirabilis, Pseudomonas aeruginosa (67.6% of sphygmomanometers), Streptococcus and Coliform species were isolated. There was no significant difference between the contamination of stethoscopes and sphygmomanometers by the isolates, except for Pseudomonas aeruginosa (t=3.49, p=0.04). Conclusions: Awareness did not match practice in cleaning the stethoscopes and sphygmomanometers in the four facilities. Staphylococcus aureus and Pseudomonas aeruginosa were the two most common organisms isolated with a significant difference (t=3.49, p=0.04) between stethoscopes and sphygmomanometers in isolation of Pseudomonas aeruginosa. To curb HAIs, health workers need to improve on their practice of cleaning stethoscopes and sphygmomanometers.

Emmanuel umegbolu