Pumping fluid is one of the crucial parts of any microfluidic system. Using electric and magnetic fields as a substitute for moving parts can have many advantages. In this study hydrodynamic and heat transfer characteristics of electroosmotic flow under influence of lateral electric and transverse magnetic field, are studied numerically. Results indicate that the dimensionless parameters such as Hartmann number, intensity of the lateral electric field, pressure gradient parameter and aspect ratio have an important role in controlling flow. It can be implied that the enhancement of pressure gradient leads to the decrease of critical Hartmann number, and this dependency can be reduced from 44% to 7% for S=0.5 to S=50 in two pressure gradients of Ω=1 and Ω=20. In addition, the reduction of aspect ratio of microchannel section leads to the increment of critical Hartmann number in a specified lateral electric field. At the end, thermal analysis is being done by consideration of the effects of magnetic and electric fields on the Nusselt number.
CoronaVirus’ is a hard hit on both Millennial consumers and marketers. It forced consumers and marketers to do the usual activities of buying and selling differently. Panic buying and herd mentality was widely noticed among millennials. Their unusual buying behavior which reflects behavior during a crisis is highly influenced by environmental stimuli. From this study, it is found that there has been a significant buying behavioral shift of global millennials in emerging markets (BRIC – Brazil, Russia, India, China; CIVETS – Columbia, Indonesia, Vietnam, Egypt, Turkey, South Africa). It is evident that the initial marketing attempts of marketers failed during COVID-19 due to the lack of understanding of the significance of environmental and marketing stimuli in consumers’ purchase decisions. This study brings out the various positive substantial changes brought about through internetization in marketing goods and services to millennial customers during the pandemic. The pandemic enabled a rapid digital revolution in buying and selling using digital/online platforms. The study suggests the application of the Black Box Model by marketers in marketing and selling decisions. The Internet has been the most important tool used by customers and sellers to access what they need. This study is useful to marketers and upcoming entrepreneurs to understand that it is the consumer’s buying behavior that triggers and pushes marketers to sell differently.
This research was conducted at SD Darus Sholah, Jember which aims to answer the main problems related to the implementation of the Student Team Achievement Divisions learning strategy in integrated thematic learning. The problem studied in this research is the Implementation of the Student Team Achievement Divisions Strategy in integrated thematic learning at SD Darus Sholah, Jember. This research approach uses a qualitative approach with the type of phenomenological research. Methods of data collection using interviews, observation and documentation. Data analysis used the interactive model of Miles and Huberman, with the process of data collection, condensation, data display, and data verification. To test the validity of the data using triangulation. The results of this study indicate that: 1) At the presentation stage, the teacher starts with story material, reviews previous material, and learning activities in teams. 2) The teacher prepares a worksheet as a guide for group work and each member can contribute, the teacher makes observations, provides guidance, motivation, and assistance if needed. 3) Individual tests in groups. 4) Score development for individuals, the teacher combines the previous score with the final score. 5) Appreciation for the team is based on the assessment of individuals in the group so that the process of group assessment recapitulation is based on individual assessment of each group. Penelitian ini dilakukan di SD Darus Sholah Jember yang bertujuan untuk menjawab pokok permasalahan berkaitan dengan penerapan strategi belajar Student Team Achievement Divisions dalam pembelajaran tematik terpadu. Permasalahan yang dikaji dalam penelitian ini, Implementasi Strategi Student Team Achievement Divisions dalam pembelajaran tematik terpadu di SD Darus Sholah Jember. Pendekatan penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian fenomenologis. Metode pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Analisis data menggunakan model analisis interaktif Miles dan Huberman, dengan proses data collection, condensation, data display, and data verifiying. Untuk menguji keabsahan data menggunakan trianggulasi. Hasil penelitian ini menunjukkan bahwa: 1) Pada tahap presentasi, guru memulai dengan materi cerita, mereview ulang materi sebelumnya, dan kegiatan belajar dalam tim. 2) Guru menyiapkan lembaran kerja sebagai pedoman kerja kelompok dan setiap anggota dapat berkontribusi, guru melakukan pengamatan, memberikan bimbingan, motivasi, dan bantuan jika diperlukan. 3) Tes individu dalam kelompok. 4) Skor pengembangan bagi individu, guru menggabungkan skor nilai sebelumnya dengan skor akhir. 5) Penghargaan bagi tim mendasarkan kepada penilaian terhadap individu dalam kelompok sehingga proses rekapitulasi penilaian kelompok, didasarkan kepada penilain individu masing-masing kelompok.
Technology and Isolation in the Information Period explores the social, political, and legal implications of the group and use of personal information in computer databases. In the Information Period, our lives are documented in digital case books maintained by hundreds (perhaps thousands) of businesses and government agencies. These case books are composed of bits of our personal information, which when assembled together begin to paint a portrait of our personalities. Technology has changed our working practices and now allows us to be connected 24/7. We have the power to Skype clients around the world and email or Tweet work colleagues at weekends, but is there a danger that having connectivity so readily available hinders our efforts to gain a better work/life balance? We often read articles about the correct way to manage technology and how to achieve a happy balance of relaxing away from work and being ‘Always On’ and ‘Always available’. For instance, many people choose a job that allows them to detach from the workplace on evenings and weekends, yet technology makes it difficult for others to switch off. Now, we are huge believers in the ability to use the internet, email, Facebook, Twitter, texting and to pick up the phone and talk to people, but because of technology more people are becoming distracted and losing focus. They can’t escape from the workplace and feel that the office follows them around via their Smartphone which demands attention 24/7. It wasn’t so long ago that when we took a holiday, we would plan ahead, make sure everything was order, inform clients of our absence and brief our teams so we could disappear off to distant shores and happily sit in the sun for a relaxing fortnight, avoiding drinking the local water, eating strange local delicacies and fending of mosquitoes. But I digress … Having technology at hand means that we still have an element of control at our workplace and the ability to deal with issues if they occur. The downside to this is managing that work/life balance again. On one hand the internet is a lifeline, but it can also become a ball and chain if we don’t take the time to unplug from it. Technology allows us to be in two places at once, but when employees struggle to find the right balance between their work and personal lives there is a chance that stress levels can increase leading to a potential loss of productivity and happiness in general. In a recent survey 70% of workers said that technology brings the stress of work into their personal lives. Many Researchers have recommended drawing a line between work communications and home. This not only benefits your well being, but benefits your employer too, as you will be coming back to work refreshed and recharged.
This paper investigates the deep learning techniques to improve radio resource management (RRM) in vehicular communication network (VCN). In this paper, the deep learning algorithms are highlighted which are used for RRM. Deep learning technique in RRM is basically used to train the model using various algorithms of resource management including network data. Various machine learning tools will be helpful to get best solutions for resource allocation in a large cellular network.
The rapid growth of wireless devices introduces a diverse range of applications and requires intelligent hardware platforms that integrate computing, sensing, and wireless connectivity in a compact systemon- chip (SoC). This paper presents a low-power, high-performance SoC platform that supports dynamic power management and secure communication. The SoC platform consists of 16-/32-bit programmable ARM9 cores, a power management unit with multiple low-power modes, analog and digital peripherals, and security engines. A complete tool-chain with an automatic platform generator has also been developed to ease and accelerate the application development. Fabricated in a 65 nm CMOS technology, an implementation of the proposed platform occupies an area of 1.0 × 1.7 mm2.
Plants produce a diverse range of bioactive compounds making them rich source of different types of medicines. The plants are mostly cultivated for decoration and to enhance the appearance of houses, gardens, road sides, and also for commercial purposes such as floral decorations in form of bouquet. They are also source of fragrant oils for perfume making and cosmetic. However only very few of these plant species have found to be used in medicine and little or no literature exit on their chemical and biological activities. Araucaria columnaris is an ornamental plant, commonly known as Christmas tree, belonging to the family Araucariaceae. Plant resin was used for the present study, antibacterial activity and GC-MS analysis of Araucaria columnaris resin was carried out. The resin was subjected to solvent extraction using decreasing polarity solvents (aqueous, methanol, ethyl acetate and benzene). TLC profiling of all the extracts gives an idea about the presence of various phytochemicals and its fractions were checked for antibacterial activity against major clinical pathogens. It was found that fraction 4 (F4) of methanolic extact showed maximum zone of inhibition against Gram positive organisms. This fraction was subjected to GC-MS analysis; the result revealed the presence of a board range of many medicinal compounds and antioxidant activity of resin of Araucaria columnaris were identified.
In this paper, an approach for formulation of generalized field data based model for cylinder head moulding operation. The aim of field data based modeling for cylinder head moulding operation is to improve the output by correcting or modifying the inputs. The goal of the research is to reduce human energy input required while performing cylinder head moulding operation. With the reduction in human energy input, automatically, the productivity of the process will also increase. The study identifies important ergonomic and other work environment related parameters which affect productivity. The identified parameters are properties of sand, physical dimensions of tools, energy outflow of workers, anthropometric data of the workers, working conditions like relative humidity, ambient temperature. Out of all the variables, responses and causes are identified. After dimensional analysis relationship between the dependent and independent parameters, a mathematical model is established having a relationship between output parameters and input. To get the optimized values model is optimized using the optimization technique. Sensitivity analysis is a tool which can be used to find out the effect of input one parameter over the other. The model will be useful for an industrialist to select optimized inputs so as to get targeted responses.
Stem cells hold great promise for tissue regeneration and have the potential to treat many incurable degenerative diseases. Cancer stem cells (CSCs), or cancer initiating cells, have the ability to self-renew and differentiate into heterogeneous lineages of cancer cells. Current stem cell therapies face limitations, such as limited stem cell sources, time consumption, tumor formation, and immune rejection upon allogeneic transplantation. Allogeneic stem cell treatments simplify stem cell manufacturing and reduce transplant time, but their therapeutic potential is limited by human leukocyte antigen (HLA)-matched donors. CSCs retain characteristics essential for tissue regeneration. However, several limitations hinder cancer stem cell reprogramming with pluripotent factors. The development of 3D culture models for tissue imitating extracellular matrix in cancer cell lines aims to enhance CSC enrichment. This mini-review focuses on a new strategy for treating incurable degenerative diseases involving in vitro and in vivo 3D cancer models and the induced differentiation of CSCs into mature normal cell types. This allows tissue survival without immune rejection and offers a safe alternative to cancer stem cell reprogramming with pluripotent factors. In conclusion, preservation and banking of allogeneic CSCs offer an alternative, readily available, and safe strategy that can be used to facilitate stem cell-based cell therapy.
The seeds of Phaseolus vulgaris are known as common beans or kidney beans. The dry seeds are eaten as pulse and are enriched with protein, fiber, starch, B vitamins (B1, B6, B9), iron, potassium and selenium. Beans also contain about 1-2 % of fixed oil. Phaseolus vulgaris is linked to anticancer, antihyperlipidemic, hypoglycemic, and antioxidant actions. The fixed oil of Phaseolus vulgaris (PVFO) seeds is extracted with hexane and used in this study to assess acute oral toxicity, analgesic (by acetic acid-induced writhing, hot plate and tail flick tests in mice) and antiinflammatory (by carrageenan-induced paw edema in rats) actions. Four groups were made (n=6): Group-I: Normal Saline Control (2ml/kg), Group-II: PVFO (2ml/kg), Group-III: PVFO (4ml/kg) and Group-IV: Standard Acetylsalicylic acid (ASA 300 mg/kg). PVFO in 2ml/kg and 4ml/kg doses demonstrated analgesic and anti-inflammatory activities, but in hot plate, results were unreliable as significant activity started after 90 minutes. A 5ml/kg dose was administered orally in mice for a toxicity test, and no toxicity symptoms were observed. Therefore, PVFO is safe for oral use up to 5ml/kg and may possess analgesic and anti-inflammatory actions.
Avian leukosis virus is recognized as an important viral pathogen in the poultry industry, resulting in salient severe economic losses due to reduced production, uneven flock growth rates, reduced growth, and immunosuppression which predispose affected birds to other infections. This study examined the seroprevalence of avian leukosis virus (ALV) in local chickens (LC) in 5 different live bird markets (LBMs) in Kaduna Metropolis. A total of 276 sera were tested for ALV p27 antigen using enzyme-linked immunosorbent assay (ELISA). An overall seroprevalence of 28.3% (78/276) was recorded in the study. At the market level, the seroprevalence of 35% (21/60), 30% (18/60), 32% (16/50), 28.6% (16/56), and 14% (7/50) were recorded for Sabon Tasha, Central market, Railway station, Kawo and Sokoto Road LBMs respectively. With regards to sex, female LC showed a significantly higher prevalence of 30.5% (46/105) compared to male chickens 26.9% (46/171) with no significant difference (P > 0.05) observed. This study established the presence of antigen to ALV in local chickens sold in LBMs. We recommend surveillance and further studies on the isolation, molecular characterization and pathogenicity of ALV in the study area.
Higher Education has an important role in the task of rebuilding a nation and it paves the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution etc; transforming human civilization in to new heights. At the start of 21st century, there is a lot of importance given to higher education. Every country realizes the value of higher education and the benefits accrue from it. There is a greater importance attached to higher education. “The social demands for higher education continue to increase. Indian higher education has a rich and complex history that spans millennia. This abstract provides an overview of the key developments in Indian higher education, highlighting its evolution from ancient times to the modern era. The history of Indian higher education is marked by the establishment of ancient centers of learning, the influence of various empires and dynasties, colonialism, and post-independence reforms. This abstract also touches upon the challenges and opportunities that have shaped the landscape of higher education in India.The history of Indian higher education can be divided into several distinct periods. In ancient India, centers of learning such as Takshashila and Nalanda emerged as renowned seats of knowledge, attracting students and scholars from across the world. These institutions laid the foundation for a tradition of rigorous intellectual inquiry
The National Youth Service Corps (NYSC) is an organization set up by the Nigerian government to involve the country’s graduate yearly in the development of the country. The one year service period has three weeks orientation period when the corps members are trained in paramilitary training. During this period, the corps members use the manual approach to supply their personal information. The manual method of information system used by the corps members is very tedious, time-consuming, prone to errors, and information modification and retrieval are practically impossible. To solve these problems, an online NYSC orientation camp information system is proposed. The proposed system is analyzed, designed and developed using Entity-Relationship Model (ERM) with an entity-relationship diagram as a defector. The architecture model is implemented using PHP and MySQL programming languages. The results showed that the researchers have developed an interactive online NYSC orientation camp information that can handle updates and modification of data more efficiently and can be accessed anywhere and anytime than the manual methods of information system. The researchers hereby recommended the developed software to the National Youth Services Corps headquarters for efficient database analysis of the corps members’ information system
If you already have a research project in mind, the research planning phase must be completed with the formulation of a wellstructured research proposal that must be submitted to an ethics committee for approval before your project can start. Generally, a research proposal contains the following elements: Title, abstract, introduction, objectives, methodology, timeline and milestones, ethical considerations, budget, appendices, and references. Whether you are a medical student or a researcher, knowing how to write a research proposal is an important skill to start any research project. This guide will give you the skills to write a successful research proposal.
Recently, novel materials like gas-sensing metal oxides, mixed metal oxides, and modified mixed metal oxides have attracted great attention owing to their key roles in monitoring environmental pollution, security in hospitals, homes, and public places, and hazardous emissions from industries and automobile exhaust. Initially, the mechanochemical (MCh) method was employed for the synthesis of the CuMnO3 catalyst and then the modification of CuMnO3 through the hydrothermal route. These synthesized catalysts were characterized by Ultraviolet Violet-Diffused Reflectance (UV-DRS) spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscopy (SEM). The average particle size obtained for 3 % Fe/CuMnO3 was found to be 14–28 nm. The present work proclaimed that among all the synthesized 1,3,5 % Fe/CuMnO3 materials, the 3 % Fe modified CuMnO3 material shows significant gas sensing properties towards highly toxic H2S gas released from sewage plants, oil, and natural gas industries, among NH3, CO2, H2S, H2, CO2 and Cl2 with moderate temperature requirements and excellent selectivity.
The main objective of this study is to examine the relationship between globalization, resource conflicts and peace –building in Africa, with particular emphasis on Nigerian’s north-central geo-political zone. The wave of globalization that has swept across the world with its attendant socio-economic and political consequences lies at the heart of this study. The debate that is raging currently amongst intelligentsias, public analysts, and the international community point to the fact that the global system has suffered increasing setbacks occasioned by the impacts of globalization and contestation for scarce natural resource endowments. The changes that have emerged for several decades in both developed and developing nations, with the latter having a greater share of repercussions, have remained largely daunting. The multiplier effects of these changes have resulted in worsening crisis situations, with a fast growth rate of intra-state and/or trans-regionalized networked conflicts, which is why Africa and indeed Nigeria, has become a hotbed for contestations recently. This work adopts a qualitative approach as a method of investigation. This work relies on classic works of experts in the broader discipline of globalization and conflict resolutions, the essence of which is to clearly define ways of ensuring absolute peace in Nigeria’s north-central zone. The paper observes that guaranteeing peace-building requires the adoption of both vertical and horizontal approaches as templates for the realization of peace objectives.
Zn1-xCdxO (x=0, 0.04, 0.06, 0.08) ternary alloys were successfully synthesized by Sol–gel method. The prepared powders were sintered at 800°C for 4hrs. The compositional, structural and optical studies were investigated by SEM equipped with EDS, XRD and UV-Visible Spectroscopy. XRD results were compared with JCPDS data and confirmed the formation of Cd doped ZnO nanoparticles with polycrystalline single phase hexagonal wurtzite structure. The crystallite size was found to decrease from 21 to 17 nm with increase in the concentration of Cd. EDS analysis revealed the existence of Cd content in ternary alloys. From Ultraviolet-visible spectral studies optical band gap vary from 3.21 eV to 3.12 eV with Cd concentration. © 2016 Elsevier Ltd. All rights reserved. Selection and Peer-review under responsibility of International conference on materials research and applications-2016.
Background In 2016, the Tanzanian government shifted the vaccine supply chain responsibilities from the Medical Store Department (MSD) to the Expanded Program on Immunization (EPI) to reduce costs. However, cost estimates that informed the decision were based on invoice value of vaccines and related supplies, rather than a proper economic evaluation study. Therefore, this study aims to compare the actual storage and distribution costs of vaccines and related supplies between MSD to EPI. Method Micro-costing approach was used to estimate resource use at MSD and EPI for the year 2018. Data were collected through a review of documents, warehouse databases, and interviews with key staff at MSD and EPI. We included both capital and recurrent costs. Microsoft Excel® was used for analysis with input data from the UNICEF forecasting tool, WHOs vaccine volume and capacity estimation tool, diesel generator calculator, and supply chain service fee estimator version 1.02. Results The total vaccine storage and distribution costs were estimated to be USD 1,996,286 at MSD and USD 543,648 at EPI. Distribution and program management costs represented 41% (USD 819,288) and 38% (USD 762,968) of the total costs at MSD, while storage and distribution costs represented 43% (USD 234,423) and 34% (USD 184,620) of the total costs at EPI, respectively. The cost drivers at MSD were fuel and transport (21%), receiving and dispatch (19%) and, program management personnel cost (14%), while at EPI were storage space (20%), program management personnel cost (18%) and fuel and transport (15%). Conclusion The storage and distribution of vaccines in Tanzania via the EPI reduced the vaccine supply chain cost to about 27% of the program costs at MSD.
Along with computer technology, the demand of digital image processing is too high and it is used massively in every sector like organization, business, medical etc. Image segmentation enables us to analyze any given image in order to extract information from the image. There are numerous algorithm and techniques have been industrialized in the field of image segmentation. Segmentation has become one of the prominent tasks in machine vision. Machine vision enables the machine to vision the real world problems like human does and also act accordingly to solve the problem so it is utmost important to come up with the techniques that can be applied for the image segmentations. Invention of modern segmentation methods like instance, semantic and panoptic segmentation have advances the concept of machine vision. This paper focuses on the various methods of image segmentation along with its advantages and disadvantages.
Metronidazole-induced neurotoxicity is a rising challenge in managing susceptible infections. The mechanisms involved in metronidazole-induced neurotoxicity are not fully unraveled. This study aimed to explore the effect of metronidazole on iron homeostasis in SH-SY5Y neuroblastoma cells. Confluent SH-SY5Y neuroblastoma cells were treated with different concentrations of 1.0, 10, 25, 50, 100, and 250 µM of metronidazole only or in combination with 20 µM iron. DMSO or culture media was used as control. Viability and ferritin assays were conducted on the treated cells. The treatments were for 24 hours, 48 hours, and 72 hours, respectively. In the viability assay, doses of metronidazole reduced the viability of SH-SY5Y neuroblastoma cells in a time and concentration-dependent manner. After 24-hour treatment, 250 µM metronidazole significantly reduced cell viability while 50 µM, 100 µM and 250 µM metronidazole reduced considerably viability only after 48-hour and 72-hour compared with control. Different doses of metronidazole 50 µM, 100 µM, and 250 µM in 20 µM iron reduced viability in a time-dependent manner in all the test periods. Metronidazole also induced a time- and concentration-dependent increase (p<0.05) in cellular iron uptake in the 48-hour and 72-hour treated cells in concentrations above 25 µM metronidazole. It is concluded that metronidazole induces a time and concentration-dependent iron overload and consequent cell death in SH-SY5Y neuroblastoma cells and this may contribute to the mechanism of metronidazole-induced neurotoxicity.
Mediterranean journal of pharmacy and pharmaceutical sciences