Diabetes is a global issue, the diabetes epidemic is expected to continue, and the burden of diabetes causes catastrophic expenditure for healthcare system. The current study aimed to determine the presentation, the clinical feature and cardio-vascular risk factors in patients with diabetes. A retrospective observational study had been conducted in out-patients department at Almustaqpal Almosherq Centre during September, 2013 till September, 2020, the total number of attended out-patients department were 1 024, 820 patients who were selected for this study. A special perform was completed for every patient, which included details about patient’s demographics, points in clinical history, relevant investigations and clinical examinations were recorded. The study reported that out of 820 patients, 66% (n = 538) was female and their age range was between 14 - 87 years with a mean age of 56.53 ± 13.49 years, 96% (n = 791) were clinically diagnosed as type II diabetes, 07% of the patients were diagnosed as pre-diabetes, the duration of diabetes ranged from newly diagnosed to more than 10 years, with 46% (n = 379) of the studied population were more than 10 years diabetes duration, 70% (581) were presented with classical symptoms of diabetes. Initial treatment for diabetes also different in the studied sample, were absent of anti-diabetic medications in 30% (n = 248) of the patients, they refused to start glucose lowering drugs, 34.6% (n = 284) of them have morbid obesity (body mass index is more than 40), 80% (n = 662) have high HBA1c (more than 8 g%), 40.3% (n = 240/596) were uncontrolled hypertension on anti-hypertension drugs, 95.6% (n = 682/713) were controlled on treatment of lipid lowering drugs. This study showing the presentation of diabetes were the common, type II diabetes, at age group between 41 - 66 years about 65%, female sex, with high body mass index, high glycated hemglobulin and uncontrolled hypertension. There is concern that diabetic patients were occurring at a high frequency in younger adults, where longer duration of illness could increase the risk of developing more complications in later life. The rate of coexist cardiovascular risk factors (hypertension, dyslipidaemia and obesity) in Libyan patients with diabetes is highlighted.

Mediterranean journal of pharmacy and pharmaceutical sciences

For a long time, cardiovascular diseases have been the leading cause of death worldwide. Machine learning has found significant usage in the medical field as it can find patterns in data. Classification models can help cardiologists to diagnose heart diseases and minimize misdiagnosis accurately. In this paper, we explored a dataset related to heart disease and compared the accuracy of 43 machine learning classification models. The dataset for this research was downloaded from Kaggle; it contained 1190 observations, 11 features (age, sex, chest pain type, resting blood pressure, serum cholesterol, fasting blood sugar, resting electrocardiogram results, maximum heart rate achieved, exercise induced angina, oldpeak, the slope of the peak exercise ST segment) and a binary target variable (no heart disease or observed cardiovascular disease). For data exploration, preprocessing, training, testing, and predictor importance analysis, we used MATLAB R2004a software and the Classification Learner app included in this software. Before training machine learning classification models, we divided the dataset into a training set (90% of observations) and a test set (10% of observations). To prevent overfitting during the training of classification models, 10-fold cross-validation was used. The result showed that the best accuracy was reached with an optimized ensemble classification model (validation accuracy: 0.9262 and test accuracy: 0.9580). After calculating the permutation importance of each feature, we observed that the most important feature among all 11 features was the slope of the peak exercise ST segment.

Ladislav végh

Abstract In every hospital, Casualty department deals with the emergency cases. These emergency cases also includes medicolegal cases like road traffic accidents, Poisoning, assaults are dealt in the casualty and detailed MLC report is made here after giving the proper primary treatment and life saving measures. The police is informed about MLC as early as possible. Important preventive measures like drawing public attention and awareness towards traumatic casualties can help in the prevention or management of unnatural (medicolegal cases). Considering the importance of above points, a one year retrospective study from 1st March 2018 to 31st March 2019 was conducted in the Casualty department of Tertiary Care Centre.

Dr. avinash harishchandra waghmode

Industrial waste is one of the most essential sources of contamination in the environment. Chromium (Cr) is a toxic heavy metal, a major contaminant in tannery wastes and its accumulation in soil and water is a major environmental concern today. In the present study, an attempt was made and investigated the status of different beneficial microbes particularly plant growth promoting rhizobacteria (PGPR) from tannery sludge samples collected from tannery effluent treatment plant at Dindugal, Tamil Nadu, India. Experiments were conducted and evaluated their chromium heavy metal tolerance abilities and plant growth promoting activities under in-vitro. Based on molecular analysis, the PGPRs were identified as Achromobacter xylosoxidans (LK391696), Azotobacter vinelandii (LK391702) and. The production of IAA was found to be high by Achromobacter xylosoxidans (46μg/ml) followed by Azospirillum lipoferum (30μg/ml). Phosphate solublization activity was also found to be positive in all these PGPR isolates. Significance of these results revealed that there is a possibility of using these potential PGPRs for bioremediation of chromium contaminated sites and also as good plant growth promoter.

Dr. saranya devi k

Background: Malnutrition is a deficiency of nutrients due to inadequate energy intake. Picky eating behavior in children could be a cause of malnutrition, but previous studies’ results were still inconsistent. This study aimed to determine the relationship between picky eating behavior and malnutrition among children aged 2-5 years. Methods: This case-control study involved 70 children aged 2-5 years in Kutukan Village, Randublatung District, Blora Regency. Malnutrition was defined as a weight-for-age Z score <-2.0 SD based on the WHO classification. Child eating behavior was evaluated using the Child’s Eating Behavior Questionnaire (CEBQ), identifying picky eaters if the food avoidance score surpassed the food approach score. Data analysis employed the Chi-Square test. Results: Boys experienced more malnutrition, with 20 (57.1%) affected, and the most affected age group was 24-35 months, with 19 (54.3%). Questionnaire processing revealed that the number of picky-eater children in the malnutrition group was 33 (94.3%), while in the non-malnutrition group, there were 31 (88.6%). Bivariate analysis showed no relationship between picky eating behavior and malnutrition in children aged 2-5 years (p=0.673; CI 95%=0.364-12.459). Conclusion: This study found no significant relationship between picky eating and malnutrition in children aged 2-5 years.

Minidian fasitasari

The use of nanotechnology in healthcare and medicine is crucial, particularly for nanocoatings. The therapeutic potential of nanocoatings on medical implants and devices is examined in this chapter. It goes into the ingredients, production processes, and health benefits of nanocoatings. Device functionality and biocompatibility can be enhanced by nanocoatings. They are essential in addressing healthcare issues including cardiovascular stents and orthopedic implants. Additionally, nanocoatings are used in medication delivery systems, tissue engineering, and wound healing. This chapter offers important knowledge on the medical applications of nanocoatings to experts and researchers. Nanotechnology has the potential to alter the medical industry, which would be advantageous for patients.

Boopathy govindarajan

This review shares historical glimpses of the art and science of urinary crystal growth in the gel. This successful journey of long and detailed research consists of theoretical and experimental knowledge. The survey consists of historical aspects of crystal growth, the development of urinary crystal growth in the gel as an in vitro urolithiasis model and the application of this model to evaluate prophylactic management against kidney stones.

Dr. salman ahmed

Rasa aushadhis are known for their uniqueness in curing the diseases with a very low dosage. These formulations are divided into two types based on their mode of preparation i.e., Single drug and Compound drug formulations. Based on their origin, the drugs are divided into three types, Herbal, Mineral and Animal. Any of these two or three together is combined to make a compound formulation. Apart from these, the other major factor which is needed for a formulation is the Rasa Panchaka of a Drug. Many of the formulations are being prepared based on their availability, keeping their Rasa Panchaka and Samprapti vighatana in mind. These formulations are designed in such a way that two or more drugs will be having one common quality, or Opposite Qualities or an Antidote of a particular Vishadravya, which can help in curing the disease. So an attempt is made to Review Tribhuvanakeerti Rasa with its Probable mode of action.

Suri abhiram

The study was conducted on glass slides to observe the growth patterns of urinary calcium oxalate monohydrate crystals and their inhibition using 5, 10 and 15% Phaseolus vulgaris seed infusion. For this purpose, a drop of gel medium (sodium metasilicate of 1.06 specific gravity and 3M acetic acid solution) at pH 5.02-5.17 was placed in the middle of the glass slide and converted into gel. A single drop of 1 M oxalic acid was dropped to the left, and 1 M calcium chloride and magnesium acetate (1:1) solution fell to the right side of the adequately formed gel. The glass slide was observed under microscope till it was completely dried. In the case of the crystal inhibition study, a drop of Phaseolus vulgaris infusion was also added on the right side just after adding calcium chloride and magnesium acetate solution. The results without infusion showed detailed morphology and aggregation patterns of observed crystals as donut, dumbbells, needles, platy, prismatic, rosette, round edges, and loose and compact aggregates. All infusions of Phaseolus vulgaris showed defective crystals. 5 % infusion inhibited crystals of all morphologies with their loose and compact aggregates except rosettes. Whereas 10 and 15 % infusion converted the rosette crystals into ineffective calcium oxalate dihydrate crystals of tetragonal bipyramidal and elongated rod shape. The microscopic study of calcium oxalate crystal growth and its inhibition is simple and provides rapid qualitative analysis of antiurolithiatic activity.

Dr. salman ahmed

Contact between pharmaceutical company representatives (PCRs) and medical practitioners is viewed by drug companies as a vital part of their marketing strategy. Studies show that PCRs employ persuasion disguised as information. Because PCRs are keenly involved in competitive marketing, they are more likely to use persuasion than information during their promotional visits. Information increases customer awareness of a particular product without influencing the preferences. Persuasive marketing directly influences a consumer’s brand preference. Positively influencing a prescriber’s attitude towards a product is essential for effective marketing since there is an association between attitude, intention and behaviour. Numerous studies find that pharmaceutical promotional interactions have an impact on physician’s perceptions and their prescribing practices. Yet, many of today's health professionals do not acknowledge their vulnerability to being misled by pharmaceutical marketing. This study demonstrate that Pharmaceutical promotion strategies do not differ greatly from those of other types of marketing, PCRs more likely to use persuasion to highlight the perceived difference of their particular brand. Persuasion often has a subtle influence that is not easy to detect and physicians should receive education regarding the drug promotion techniques used by pharmaceutical companies. Persuasion often has a subtle influence that is not easy to detect. Overconfidence is a major risk factor for being misled. This analysis highlights some critical aspects of persuasive communication by PCRs in promotional visits. It will help prescribers to interpret, evaluate and respond appropriately to manipulative behaviour by PCRs.

Mediterranean journal of pharmacy and pharmaceutical sciences

Background: Idiopathic Parkinson's disease (PD) is a central nervous system degenerative disorder with an unknown etiology. PD is the second leading cause of neurological impairments. Exercise therapy treatment is commonly used for PD to improve health and decrease the functional limitations. Exercise therapy includes Strengthening, aerobic, agility etc.. Objective: To investigate the evidence on efcacy and limits of strength training in rehabilitation of Parkinson's disease Method: A comprehensive search on pubmed, clinical keys database using keywords Parkinson's disease, physical therapy, strength training ,resistance training. The studies including Randomized controlled trails and systematic reviews published since 2005 are reviewed. Results: 36 studies identied through database searching. 25 studies are excluded due to duplicates, irrelevance, based on titles, outcome diversity. 5 systemic reviews and Meta analysis, 6 RCT are included. Review and analysis of articles is going on Conclusion : The result of this review suggests that strength training program can be effective in people with mild and moderate parkinson's disease. It can improve functional independency with increased muscle strength, gait parameters, posture and balance, all of these positive role on participation and quality of life.

Nagarjuna narayanasetti

WSN is a low-power system and are often used in numerous monitoring uses, such as healthcare, environmental, and systemic health surveillance, in addition to military surveillance. It is important to reduce network resource usage since many of these applications need to be installed in locations that are virtually inaccessible to humans. Many protocols for WSN to extend the presence of the network have been established to solve this problem. In the energy efficiency of WSN networks, routing protocols play an important role since they help minimize power usage and response time and provide sensor networks with high data density and service quality. This study also employed a Hopfield neural network and the findings from this study are presented next to each other to enable comparison. This paper also discusses how to easily and accurately capture and handle WSN collisions. Future experiments that require the usage of neural networks and so many fuzzy structures will be able to prevent a crash in these respects.

Mohd haroon

Ayurvedic formulations are of three types, Herbal, Mineral and Herbo-Mineral. Of which, Herbomineral is prepared either by Khalweeya or by Bhasmeekarana procedures. The quality of Bhasma depends on the number of putas given. Rasa Bhasma is one such kind of a Herbo-mineral preparation which can be obtained by Puta procedure as described in texts of Rasa Shastra. Though there are different procedures mentioned for preparation of Rasa Bhasma, maarana done with Gorvara puta seems to be an apt way to obtain the final product. Puta is the generalised way of heat application used during the pharmaceutical procedures of Rasa dravyas, where the purified organic Metal/Mineral is converted completely into powder form which can be absorbed easily into the body without causing any ill effects. Different types of Puta have been explained for bhasmeekarana of different metals and minerals. Among them, certain putas have been mentioned where Mandaagni plays a crucial role in Maarana (Incineration). These Mandaagniputas are in use of preparing certain Bhasmas like ShilajitBhasma, HaratalaBhasma, GouripashanaBhasma, and PaaradaBhasma. As these drugs are having relatively low boiling and melting points when compared to other dravyas, and are easy to evaporate when exposed to high temperatures, they need a standardized quantum of heat by which they can be transformed into Bhasma. Gorvara puta is one such kind where agni plays a major role in the preparation of Bhasma. So, the present study A Comprehensive Study of Gorvara Puta in Preparation of Rasa Bhasmahas has been under taken.

Suri abhiram

Pedagogical leadership has become an emerging and essential debate in the field of educational administration and leadership. This was a result of the shift from the hierarchical type in the past to a more inclusive, collaborative, and participative leadership. Previous studies indicate the furtherance of the inquiry into pedagogical leadership since it is a work in progress. For this reason, a systematic literature review mapped the literature relevant to pedagogical leadership. The review drew the lines between the empirical and theoretical-conceptual contributions, including the methodologies considered in both contributions. The results have implications for a more robust theoretical-empirical model or framework of pedagogical leadership applicable to specific levels of education, especially higher education contexts. The study also implies applying pedagogical leadership in the team, at departmental and organizational levels. Results imply promoting the culture of pedagogical leadership.

Manuel caingcoy

The motto behind the keenness of urban areas has become unmistakable in current cities because of the rise of installed and associated shrewd gadgets, frameworks, and innovations. It is possible to connect every object to the Internet. As a result, in the impending Internet of Things era, the “Internet of Vehicles-IoV” will play a critical role in newly developed dazzling urban communities. The IoV can possibly address different traffic and street wellbeing issues successfully to forestall deadly crashes. In any case, a specific test of IoV, particularly in “Vehicle-to-Vehicle” as well as “Vehicle-to-Infrastructure” communications, guarantees quick, in order to transmit securely and exact performance of the information. The above effort is modifying Blockchain innovation for continuous application called RTA to meet “Vehicle-to-Every thing-V2x” communications problems in order to overcome these challenges. As a result, the main goal of the study is to develop a Blockchain-based IoT framework for establishing communication security and creating a completely decentralized computing platform. Research methodology used here is divided into two major sections. In the part 1 presented below, authors discuss the traceability and optimization over Merkle trees. The second section deals with implementing an actual blockchain with our optimized Merkle tree as the underlying technology to represent a distributed trust based ledger.

Dr h shaheen

This paper examines India’s diplomatic stance towards Israeli settlements in the Palestinian territories, focusing on the complexities of the Israeli-Palestinian conflict and India’s historical relations with both sides. The issue of Israeli settlements has been an issue and a obstacle to peace in the region. As a prominent global player and staunch supporter of Palestinian rights, India finds itself in the delicate position of balancing its traditional support for the Palestinian cause with its growing strategic ties with Israel.The article delves into the evolving dynamics of India’s foreign policy and the factors influencing its stance on Israeli settlements. Analyses India’s historical suppor t for Palestinian self-determination and its voting record in international forums not supporting Israeli settlements. It also examines India’s growing economic and defence cooperation with Israel, which complicates its position on the issue of settlements.

Dr gedam kamalakar

In the present study the effect of the ethanol extract of Culcasia falcifolia on the neurotransmitter levels were evaluated. Pentylenetetrazole (PTZ) (60 mg/kg body weight, i. p) was administered to all the groups of mice to induce convulsions. After observing the convulsion, all groups rats were sacrificed, whole brain was dissected out and separated the forebrain. The brain tissue was homogenized and then centrifuged. The aqueous phase was taken for the assay. The reading was obtained using spectroflurimeter. The result of the present study shows that the ethanol extract of Culcasia falcifolia at the dose of 200 and 400 mg/kg body weight significantly increased the level of inhibitory neurotransmitter GABA and also showed significant increase in the levels of dopamine, noradrenalin and serotonin when compared to seizure control group (PTZ treated group) and was almost equivalent to control group. The findings of the study showed that the extract at 200 and 400 mg/kg body weight significantly (p<0.001) increased the levels of GABA, dopamine, serotonin and noradrenaline. The ethanol extract of Culcasia falcifolia exerted antiepileptic activity by decreasing seizure susceptibility to pentylenetetrazole-induced seizure in mice due to restoration of GABA, serotonin, dopamine and noradrenaline concentration levels in mice brain.

Gracelyn portia

Cystic fibrosis is a challenging disease which creates many complications. The impact caused from cystic fibrosis on an adolescent is a challenging phase for their lives. Negative impacts like the society’s pressure, anxiety and depression are few common reasons that are being unspoken and ignored due to complexity of the disease. This study is aimed to identify the necessary gaps and educate the necessary policy makers and CF center health care team to have a better understanding about the context of the aftermath of cystic fibrosis and enhance better patient care. More over this systematic review also points out the main trends in this field of study. Qualitative study and quantitative are prominently used research methods to gain an understanding the about the gaps in the research. However, there is still a scarcity of quantitative and mixed research methods. Furthermore, limitations such as language, cultural influences were identified whilst going through the analysis. Overall through the information given in the following in this study more information regarding that warrants answers can be identified which will lead to proper care towards the teenagers who suffers from cystic fibrosis

Chanitha pemasena

The presented mathematical model is used to form machine cells, optimize costs of exceptional elements and design the shop floor layout for various demands of components. The complete similarity measure algorithm forms machine cells and part families in a refined form. Later, exceptional elements are eliminated in linear programming optimization model by using machine duplication and part subcontract. Then the shop floor layout is designed to have optimized material movements between cells and within a cell. The performance evaluation of cell formation algorithm is done on case studies of various batch sizes to give the process capability compared with other similar methods. The result from a linear programming optimization model is cost savings, machines duplicated, parts subcontracted, inter intra cellular movements. Finally, the output of inbound facility design is the floor layout which has machine cell clusters with optimized floor area.

S ramesh

The wet coating of anhydrous borax powders with stearic acid (SA) to reverse their inherent hydrophilic surface properties was investigated. The coating procedure was based on the results from a previous study that revealed that the stearic acid solution (2 wt. % SA) mixed for 60 minute at 750 rpm on the magnetic stirrer was sufficient for the surface modification of anhydrous borax. For the experiments, stearic acid powders were first dissolved in water at 80 °C. The mixture obtained by adding anhydrous borax powders to this solution was vigorously mixed on a magnetic stirrer to initiation and completion the surface modification. Each of these solutions was then filtered using a filter paper to separate the undissolved particles, and the residue on paper was dried at 50 °C for 48 h until constant weighing was obtained. Wettability has been accepted as a key parameter for success in wet coating treatment. This parameter gained via the experimental characterization technique was used for an evaluation of the powder properties. The degree of wettability of anhydrous borax powders was measured and compared both after their surfaces were coated with stearic acid and after they were treated with water for a certain period of time in an aqueous environment. The stearic acid coating made the powder hydrophobic and this property was highly preserved after washing.

Journal of characterization