Dosing in the neonatal intensive care unit

Over the years, pharmacy has developed from a simple floor stock system to a complex unit dose, I.V. additive, and clinical pharmacy program. This development would have never been possible without the support of the nursing, medical, and administrative staff. The support of obtained slowly by developing services that increase the pharmacist's credibility as a team member concerned with the pediatric and neonate patients. These services include a unit dose program, I.V. additive program, drug information services, and pharmacy medication program. One area in which pharmacist does not obtain a background from generalized training is the area of pediatric dosing. Pediatric pharmacists must learn in clinical practice the proper dosing of the pediatric patient and neonate patient. The dose must be checked periodically. In the premature or newborn infant, the pharmacist must consider the immature renal and hepatic function so that he/she does not overdose initially and then underdose as the infant grows and matures. Neonates are a special group of children, they are less than 30 days, and within this group preterm babies (that means less than 37 weeks). Determining the correct dose for drugs used to treat neonates is a critically vital factor. Prematurity affects kidney and liver function and the proper adjustment of drug doses is crucial [1]. The absence of drug level necessitates the adjustment of drug doses and the presence of qualified oriented dependable pharmacists. Drug doses are not numbers, or decimals used within the therapeutic range. Neonatal Intensive Care Unit (NICU) needs a system for the calculation and preparation of drugs [2].

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Follow-up regularity in eye-care among disease conscious population in delhi-ncr: a gender-based retrospective study

Abstract---In contemporary society, most females are deprived of proper education, healthcare, job opportunities, etc., to uphold family customs, patriarchal dominance, and occasionally negligence towards the feminine gender. According to researchers, gender inequalities in health care, especially in eye care, are evident between accessing the care and getting treatment in developing countries. Therefore, we aim to measure the gender-wise eye-care follow-up regularity in accessing long-term glaucoma consultation among various age groups with a sample size of 564 in Delhi-NCR, India. The age groups (in years) are 15-29 (Group I), 30-44 (Group II), 45-59 (Group III), 60-74 (Group IV), and 75 and above (Group V). Groups I to V show, intragroup males have higher odds of getting regular eyecare by 20% (OR 1.20, 95% CI 0.413 to 3.4871), 2.08% (OR 1.0208, 95% CI 0.4637 to 2.2472), 3.4% (OR 1.034, 95% CI 0.6369 to 1.6787), 8.46% (OR 1.0846, 95% CI 0.6783 to 1.7344), and 45.83% (OR 1.4583, 95% CI 0.4575 to 4.6484) respectively. The probable causes of gender-wise irregularity are lack of seriousness, financial limitations, dependency, loneliness due to widowhood, etc. To make eye-care services equally accessible to everyone, healthcare agencies should first take various progressive policies to overcome gender-wise socio-economic barriers.

Dr. Ashwani Kumar Ghai Dr. ashwani kumar ghai

Acceptance of covid-19 vaccine among general population and students in benghazi, libya: a cross sectional study

The most successful and cost effective method for control the COVID-19 pandemic is the vaccination. Currently, there are different COVID-19 vaccine introduced into Libyan market. This study aimed to evaluate and compare the acceptance of COVID-19 vaccine among general population and students in Benghazi city. A cross sectional survey was conducted during March 2021 among 440 respondents (240 general populations and 200 students) using a self-administered questionnaire. The results were considerably similar among the two groups of participants. Only 10.9% said that they infected with COVID-19 during the pandemic period. About two thirds of the respondents agreed to be vaccinated against COVID-19 when available whereas the majority said they would wait some time before taking the vaccine (71.4%). Approximately, one third of the participants preferred the Sputnik vaccine, 24% preferred the Pfizer and BioNTech and 19.2% preferred Oxford (AstraZeneca) vaccine. More than a half (55.9%) of the participants are refused to pay for the vaccine. The majority of the respondents do not think the vaccine alone will be enough in protection against the COVID-19 (79.8%). There was no significant association between general population, students and the COVID-19 vaccine acceptance (p = 0.776). Additionally, there was no significant correlations between socio-demographic data and attitudes of the respondents with the acceptance of COVID-19 vaccine (p > 0.05), except for using hand sanitizers daily was significantly associated among the general population (p = 0.008). In conclusion, although, the general population and students have a good acceptability to the COVID-19 vaccine, more education health programs and promotion are wanted to reduce the vaccine hesitancy by declaring the importance of the vaccine, showing sufficient data stabilize the vaccine safety.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

University students’ fear of success from the perspective of positive psychology

The aim of this study was to examine university students’ fear of success from the perspective of positive psychology. Two objectives were addressed: first, analyzing the relation between fear of success, optimism, self-esteem, self-efficacy, and search for meaning in life; second, exploring the variance of the fear of success, taking into account the affective dimension of the self (self-esteem) and search for meaning in life. The results confirmed that fear of success was positively related to search for meaning, and negatively to optimism, self-esteem, and self-efficacy. The variance of the fear of success was explained by the self-esteem and search for meaning in life. Implications for school psychologists were discussed.

Elena stănculescu

Training &development initiative for entrepreneurship promotion by tgb -resti : an analysis from state level bankers committee database

Rural Self Employment Training Institutes (RSETIs) functions as a structural framework for skill development & entrepreneurship development training laid down by Ministry of Rural Development, Government of India in the year 2009. The concept of RSETI is bagged from the RUDSETIs (Rural Development & Self Employment Training Institutes), the brain child of Dr. D. Veerendra Heggade. RSETIs have 65 approved courses as per National Skill Qualification Framework (NSQF) under which they offer different types of Entrepreneurship Development Programme (EDP). All the programmes are short term residential training with 2 (two) years hand holding support. State Level Bankers Committee data revealed that through the RSETI training, huge number of unemployed youths started their own enterprise with or without bank finance and also getting the scopes of Self-employment. This particular study took a humble effort to publicize the role of TGB-RSETI in Tripura in respect to unemployment reduction through entrepreneurship development. The entire study is based on secondary data (2009-10 to 2022-23) retrieved from SBLC, Tripura website data.

Md. Abdur Rahman Choudhury Md. abdur rahman choudhury

Le tafal-djéguélé : une pratique et expression culturelle à l’épreuve des mutations sociales

Le 05 décembre 2012, les pratiques et expressions culturelles liées au balafon des communautés sénoufo du Mali, du Burkina Faso et de la Côte d’Ivoire ont été inscrites sur la Liste représentative du patrimoine culturel immatériel de l’humanité. Le tafal-djéguélé est une pratique et expression culturelle liée au balafon des Sénoufo de Côte d’Ivoire. Deux raisons principales fondent son usage : amener les laboureurs à la houe à se surpasser d’une part, et magnifier les valeurs des senambélé1 d’autre part, notamment celles en rapport avec le labour étant donné que le sénoufo est agriculteur par essence. Toutefois, en raison de certains changements sociaux, le tafal-djéguélése pratique de moins en moins. Cette situation prive le senanw d’aujourd’hui d’un cadre majeur d’enseignement et de diffusion de valeurs, et pose ainsi la question de leur transmission aux générations actuelles et futures. Cet article vise à démontrer comment la faible pratique du tafal-djéguélé empêche de nos jours la transmission de "valeurs- références" en pays sénoufo, mais aussi à proposer des pistes de solutions.

Assanvo

Retained umbilical venous catheter: a preventable complication

To the editor, Umbilical venous catheter (UVC) is a widely used venous access device in neonates of any gestational age due to the immediate accessibility of the umbilical vein and the simplicity of the procedure of its placement. Several complications of UVC have been reported, including the thrombotic and infective ones, its dislodgement, and embolization. [1] Retained UVC is an uncommon complication and needs prompt intervention to prevent its migration. We present a case of retained UVC and the algorithm for managing such cases.

Karishma Karishma

The theories of corporate governance and suggested solutions to its legislation completion in vietnam

Currently, there are three popular theories of corporate governance widely applied in the field of jurisprudence worldwide. They are Agency Theory, Stewardship Theory, and Stakeholder Theory. Based on these theories, the article focuses on clarifying legal issues about corporate governance, thereby suggesting solutions to the improvement of corporate governance legislation in Vietnam at present time

Iaeme

Antiurolithiatic effects of pentacyclic triterpenes: the distance traveled from therapeutic aspects

Globally, approximately 12% of the population is inflicted by various types of urolithiasis. Standard treatments are available to avert and treat urolithiasis, but with significant adverse side effects. Pentacyclic triterpenes represent a group of naturally occurring compounds with immense potential as treatments for kidney stones. This review aims to provide an integrative description of how pentacyclic triterpenes can effectively treat calcium oxalate urolithiasis through various antioxidant, anti-inflammatory, diuretic, and angiotensin-converting enzyme inhibition mechanisms. Some pentacylic triterpenes showing promising activities include lupeol, oleanolic acid, betulin, and taraxasterol. Moreover, future perspectives on developing pentacyclic triterpenes in formulations/drugs for urinary stone prevention are highlighted. It is anticipated that compiled information would serve as a scientific baseline to advocate further investigations on the potential of pentacyclic triterpenes in urolithiasis remediation.

Dr. Salman Ahmed Dr. salman ahmed

In vitro microscopic study of calcium hydrogen phosphate dihydrate crystals growth patterns

The study aims to explore the possible morphological features of calcium hydrogen phosphate dihydrate (brushite) crystals on a glass slide. The study was conducted on a glass slide under a microscope to observe the growth patterns. As a result, needle, platy, star shape, and tetragonal bipyramidal crystals were observed. Different patterns of platy crystals, like plates with spatial branches and radiating assemblages of platy crystals, were also found.

Dr. Salman Ahmed Dr. salman ahmed

Measuring vietnamese social work students’ and non-social work students’ attitudes toward poverty and poor population

The paper reports the results collected from social work students (SW) and nonsocial work students (NSW) of Ho Chi Minh City Open University (OU) through attitudes toward poverty and poor people in Vietnam. The Attitude toward Poverty Short Form (ATP-SF) 21-item (ATP-SF) scale, developed by Yun & Weaver (2010), was used for the data collection. The sample of this study comprises 180 students enrolled in three disciplines: social work (n = 86), law (n = 34), foreign language (n = 30) and economics (n = 30). The questionnaire was used to collect the data for the study. Cronbach’s alpha and independent t-tests were run to compare means between two groups of students. All students voluntarily participated in the survey.

Le Minh Tien Le minh tien

Antiurolithiatic plants: multidimensional pharmacology

Urolithiasis has been a common problem for centuries and has a high recurrence. This review aims to provide comprehensive information about traditionally used antiurolithiatic plants and their scientifically proven pharmacological activities like analgesic, anti-inflammatory, antioxidant, astringent, demulcent, diuretic, litholytic, lithotriptic, antiurolithiatic, antispasmodic, ACE inhibition and Phospholipase A2 inhibition as a plausible mechanism of action. A total of 503 species, 365 genera and 119 families were cited for treating kidney stones. The most cited families are Asteraceae (41), Fabaceae (34), Lamiaceae (26), Apiaceae (21), Rosaceae (19) and Poaceae (16). The most commonly used plant parts are root and rhizome (25%), mode of preparation decoction (62%), and oral administration route in all cases. This review will provide the opportunities for the future research and development of new natural antiurolithiatic compounds.

Dr. Salman Ahmed Dr. salman ahmed

Medicinal plants with non-steroidal anti-inflammatory-like activity

Inflammation is a natural aspect of the immune system's response. Pain, redness, heat or warmth, and swelling are the four major symptoms of inflammation. Plants can generate a vast range of phytochemical substances as secondary metabolites, all of which have anti-inflammatory properties. Herbal medicines are significant cures for the treatment of a variety of disorders around the world. Medicinal plants are made up of roughly 7500 species, with representatives from about 17,000 higher flowering plant species. Even when synthetic chemistry has advanced beyond expectations, the utilization of natural products in the production of medications utilized in modern medicine is unrivalled. Anti-inflammatory medicines can help to reduce tissue damage and improve patient comfort by interfering with the pathophysiology of inflammation. As a result of the huge number of species available for investigation, the effective creation of new naturally occurring anti-inflammatory medications relies mostly on a multidisciplinary approach to finding new compounds. Despite the fact that many review articles have been written in this area, the vast majority of them only looked at the subject from a regional perspective. Various non-steroidal anti-inflammatory medicines have been proven to alleviate pain and inflammation by inhibiting the isoform of cyclooxygenase enzyme's digestion of arachidonic acid, hence lowering prostaglandin synthesis. Non-steroidal anti-inflammatory medicines come with a slew of negative side effects. Thus, there are, however, medicinal herbs that have anti-inflammatory therapeutic properties with a little or no negative side effects.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Junk food-induced obesity- a growing threat to youngsters during the pandemic

Introduction: Obesity has been declared an epidemic that does not discriminate based on age, gender, or ethnicity and thus needs urgent containment and management. Since the third wave of COVID-19 is expected to affect children the most, these children and adolescents should be more cautious while having junk foods, during covid situations due to the compromise of Immunity in the individuals and further exacerbating the organ damage. Methodology: A PAN India survey organized by the Centre for Science and Environment (CSE) among 13,274 children between the ages 9–14 years reported that 93% of the children ate packed food and 68% consumed packaged sweetened beverages more than once a week, and 53% ate these products at least once in a day. Almost 25% of the School going children take ultra-processed food with high levels of sugar, salt, fat, such as pizza and burgers, from fast food outlets more than once a week. Children and adolescents who consume more junk food or addicted to such consumption might be even more vulnerable during the third wave, which will significantly affect the younger category. Conclusion: There is an urgent need to spread awareness among children and young adults about these adverse effects of junk food. There is no better time than now to build a supportive environment nurturing children and young adults in society and promising good health.

Ankul singh

A novel approach for productivity improvement of a man machine system – a field data base model way

A Man-Machine System means an activity occurring/occurred with the involvement of a human being with the help of some tools used to interact with the material. In small foundries, the moulding process is manual & labours have to work in different psychological moods, stress, and strain, without training on ergonomic posture, in different environmental factors such as temperature, vibrations, noise dust which affects productivity and also the amount of human energy input to produce the component. This paper makes an attempt to develop a mathematical model to relate productivity with various parameters and identify the most sensitive parameter to control productivity.

Rahul bachute

Cardiopulmonary endurance in post covid-19 patients

Long periods of free-movement Restrictions may negatively affect Cardio-Pulmonary fitness and health. As, the COVID-19 virus primarily affects Respiratory system, and also associated with cardiovascular disease, can induce the following complications like thrombosis, myocardities, Interstitial pulmonary fibrosis, diffuse alveolar damage and persistent decline in lung function, as the lung capacity decreases it may results in decrease in Cardio Pulmonary endurance. The Present study investigated changes after the COVID-19 confinement in total distance covered in 6 minutes by patients and correlation between 6 minutes walk test vs. oxygen saturation; Results suggest that the Mean ± SD of age is 43.4 ± 10.8years. Male: Female 1:0.5.Mean ± SD of total distance walked in 6 minutes by patients is 443.5 ± 55 compared with Hypothetical mean (normative value) is 571 ± 90.Correlation between Total distance walked in 6 minutes vs. oxygen saturation is r = 0.055.

Nagarjuna narayanasetti

Psychological predictors and mediators of subjective well-being in a sample of romanian teachers

The study examined psychological predictors and mediators of teacher subjective well-being. Participants included 174 teachers from urban middle and highschools. The first objective was to explore the psychological correlates of the teacher SWB: self-esteem, general self-efficacy (core self-evaluation), teacher self-efficacy, optimism (cognitive trait related to the psychological well-being), and perceived social support (psychosocial trait related to the psychological wellbeing. The second objective was to investigate the mediating role of self-efficacy in the association between optimism and subjective well-being. The third objective was to explore the mediating role of teacher self-efficacy in the relation between perceived social support and teacher subjective well-being. Correlation, linear regression and mediation model analyses through the Sobel test were computed. Results confirmed the research assumptions. The findings of this study enhance the understanding of personal factors associated with teacher subjective wellbeing. The constructs linked to subjective well-being (predictors and mediators) could be target of school psychologists’ interventions, in order to have more engaged and performing teachers in schools. The findings were discussed in the context of designing the interventions for enhancement of the subjective wellbeing among teachers.

Elena stănculescu

The twenty-five most cited articles about adductor canal block: a bibiliometric analysis from 1980 to 2022

Introduction: Loco-regional anesthesia role is increasingly important in surgery, especially in postoperative pain control. Using ultrasound-guided techniques has made the loco-regional approach increasingly safe and manageable, guaranteeing excellent analgesic results and patient compliance. This bibliometric research aimed to identify the most influential papers on the adductor canal blocks and outline their characteristics. Methods: All articles published from 1980 to 2022 were included in the Web of Science, PubMed, and Scopus databases and found using the keywords “Adductor canal block” or “Saphenous nerve block” or “Peripheral nerve block” or “Hunter canal block” or “Subsartorial canal block” or “ACB” or “Knee” or “TKR” or “TKA” or “Analgesia” or “Arthroplasty” or “Replacement” in the title section had bibliometric analysis performed. The first 25 papers were selected and analyzed by the number of citations. The correlation between numerical variables was evaluated using the Pearson Correlation coefficient. Results: Literature screening found 252 publications. One hundred ten were only about the adductor canal block. Of these, 25 articles were selected for our bibliometric study, published in 8 different journals and with a total number of citations equal to 1.457. “Regional Anesthesia and pain medicine” journal – with 9 articles – was the one that produced the most. There was a significant strong correlation between the n. of citations and the citation rate (R = 0.84, p < 0.001). Conclusion: The purpose of this study is to be a guide on regional anesthesia and, particularly, on adductor canal block, making the most effective as well as the most cited articles available to anesthesiologists or other researchers interested in this topic.

Dario Cirillo Dario cirillo

Hypotensive activity of melilotus officinalis (l.) pallas

Melilotus officinalis (L.) Pallas. is used traditionally to treat hypertension and chronic venous insufficiency. The high prevalence of hypertension and the side effects of antihypertensive drugs potentiate us to evaluate Melilotus officinalis. The hypotensive effect of Melilotus officinalis butanol fraction (MOBF) was investigated in anaesthetised normotensive rats. The doses of 60, 80 and 100 mg/ kg, i.v., produced a significant (P<0.05) decrease in blood pressure. The statistically non-significant reduction in blood pressure was shown by 20 and 40 mg/ kg, i.v. These results suggest that Melilotus officinalis exhibited a hypotensive effect in normotensive rats. However, further evaluation of compound-related activity is required.

Dr. Salman Ahmed Dr. salman ahmed

Importance of action research

Action research is such a process by which B.Ed. pupil teacher attempt to study their problems scientifically in order to guide, correct and evaluate their decision andaction There are two important components of action research:(1) the consumer are the researches and (2) the research take place where there is a felt need of a solutionof a problem and when the results can be put in practice.The steps in action research are – identification of a problem area, the selection of a specific problem and the formulation of a hypothesis, the accumulation of evidence,the inference from this evidence and the continuous retesting.The importance of action research that its lies in the fact that this helps in finding quick solutions of immediate problems which search by b.ed. Students , administratorand teacher. Action research is a way to find problems and their solution S.M. Corey has developed this research technique. Objectives of action research are – processin school practice, progress of a teacher, improvement or curriculum, increase in knowledge of administrator or inspector. Need, interest, discipline, social problems,learning problem, curriculum and teachers are the field of action research. There are various steps of action research such as specific problem .Causes, hypotheses,experiment and conclusion. Outline the action research is also mentioned. Action research has been proven most beneficial in the field of diagnostic education

Kamal Singh Kamal singh

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