A 25-year-old male presented with vaguely painful and pruritic vesicles and bullae on the oral cavity, abdomen, and superior limbs with symmetrical dissemination, which appeared over the past 3 weeks. No clinical history of importance. The physical examination showed a pallid and prostrated patient, with arterial hypertension (190/110); with several symmetrical dermal vesicles and bullae located on the abdomen and superior limbs (Fig. 1) and on the oral cavity varying from 1.5mm to 4 cm. No lymphadenopathy and sigs of arthritis were identified. Laboratory tests revealed a complete blood cell count with hemoglobin levels of 10.5 g/dL (12.7–15.7 g/DL), leukocytes of 2956/mm3 (4.3–10.7 × 103), and platelet count of 120,000/mm3 (150–350 × 103). Urinalysis shown proteinuria, hematuria, and leukocyturia. The direct Coombs assay, anti-nuclear antibodies, anti-double-stranded DNA, and anti-histone were positive. Histopathological analysis reported subepidermal discontinuity associated with neutrophilic infiltrate and direct immunofluorescence was positive for IgG, staining the basement membrane. Elisa was positive for antibodies against type VII collagen. The diagnosis was bullous systemic lupus erythematosus (BSLE) and he was treated successful with rituximab due to poor response to steroid use.

Karishma

The Construction Industry is one of the industries contributing highest GDP in Indian economy. The material that is most chosen in construction Industry is concrete. Concrete is a material made with Cement, Fine aggregate in the form of sand, Coarse aggregate in the form of gravel and water. With increasing scarcity of sand, construction works are coming to jolt and thereby increasing the need for choosing an alternative material. Vermiculite is a material which after exfoliation can be used as a filler material replacing sand partially without affecting strength much. One more material Granite (by product which is a waste is causing lot of environmental Issues), produced from granite industry, is available in India in several million tons. Coarse aggregate generally used is a crushed aggregate obtained from rocks like granite, basalt and soon. Recycled aggregate is an aggregate which is obtained after demolishing of an existing building, which is a waste causing economical in balance and which if put into use can not only decrease the construction cost but also make this waste into a better use. In the present study, for a M35 grade of concrete, Vermiculite (0, 5%, 10% and 15% of weight of sand) and granite powder (fixed at 10% of weight of sand used) is used to replace sand partially and in the place of normal coarse aggregate, recycled aggregate is used which is 20 mm passing and 12 mm retained After preparation of Mix-Design(1:1.83:2.69 with w/c ratio of 0.38) the concrete cubes are casted to test for compressive strength after curing for 28 days, 56 days and 90 days. Forsec brand super plasticizer is used to take care of workability requirements. Durability test in the form of resistance to attack of sulphuric acid was conducted along with compressive strength. The test results were promising at 10% replacement levels of Vermiculite.

Kiran kumar narasimhan

Green computing is focusing on reducing the energy consumption, resource usage, carbon dioxide emission. It was found that Last year, Google used about 12.4 terawatt-hours of electricity. Energy consumption in data centers is reduced by decreasing the resource utilization that is by switching off or shifting the computing nodes to sleep mode. But when the servers are being used the energy consumption is minimized by using energy efficient scheduling and optimization techniques.In WNS the sensor nodes are deployed in remote areas, these sensors are powered by battery that decreases the lifetime, therefore by using energy efficient techniques can increase the uptime of the battery-operated devices in WNS. This work studied various energy efficient techniques that minimize energy consumption usage in Data Centers (DC) and the algorithms that increase the uptime of the battery-operated device in (WNS) Wireless Network Sensors.

Dr h shaheen

Although the importance of service quality has been recognised, few studies have addressed service quality in hotels from the perspective of employees. Therefore, this study aims to measure the service quality of four and five-star hotels in Jordan from the employees’ perspective based on the SERVQUAL model. The current study was carried out by measuring the data gathered according to a five-point Likert scale. A quantitative survey method was applied, and therefore the SERVQUAL instrument was used to measure service quality. Data obtained from a sample of 238 respondents drawn from ten four- and five-star hotels in Jordan were analysed with the SPSS software based on descriptive statistics. The study’s findings indicated that service quality of five-star hotels in Jordan was higher than that of four-star hotels.

Mukhles m. al-ababneh

Teaching and learning computer programming is challenging for many undergraduate first-year computer science students. During introductory programming courses, novice programmers need to learn some basic algorithms, gain algorithmic thinking, improve their logical and problem-solving thinking skills, and learn data types, data structures, and the syntax of the chosen programming language. In literature, we can find various methods of teaching programming that can motivate students and reduce students’ cognitive load during the learning process of computer programming, e.g., using robotic kits, microcontrollers, microworld environments, virtual worlds, serious games, interactive animations, and visualizations. In this paper, we focus mainly on algorithm visualizations, especially on the different models of data structures that can be effectively used in educational visualizations. First, we show how a vector (one-dimensional array), a matrix (two-dimensional array), a singly linked list, and a graph can be represented by various models. Next, we also demonstrate some examples of interactive educational algorithm animations for teaching and learning elementary algorithms and some sorting algorithms, e.g., swapping two variables, summing elements of the array, mirroring the array, searching the minimum or maximum of the array, searching the index of minimum or maximum of the array, sorting elements of the array using simple exchange sort, bubblesort, insertion sort, minsort, maxsort, quicksort, or mergesort. Finally, in the last part of the paper, we summarize our experiences in teaching algorithmization and computer programming using algorithm animations and visualizations and draw some conclusions.

Ladislav végh

The present study focused on analysing the FDI inflow in Electronics industry form year 2007 to 2018 in country and role of FDI in development of the electronic industry in India. As well identify the current status of Electronics industry in world and the share of India in the same. The present research work also attempted to take overview of various policies introduced by Government of India to promote the FDI in Electronics industry. The FDI inflows statistics reveals that the separate category of Electronics sector is created in year 2007 by DIPP for recording FDI inflow. And sector specific data published in DIPP factsheet revels that this industry has attracted 0.55 % of total cumulative FDI inflow in country till December 2018 which is very negligible share of overall FDI in country. The overview of policies revels that NPE–2012 to New NPE-2018 had attempted to provide multiple incentives for Foreign Investors to establish their electronic manufacturing facilities in country but very negligible response has been seen in response of the same. Further results of study reveals that due to various FTA’s & being signatory of WTO’s ITA-1 in year 1996 leads toward reducing competitiveness of electronic manufacturing in India and country become net importer of approximately 50% of overall domestic need of electronics products.

Anshuman vijay magar

The objective of this research was to investigate the effect of initial chick weight at the first day of the hatch on subsequent performance of Iraqi local chickens. 150 unsexed chicks of local chickens weighted at first day of hatch then divided to five groups (A, B, C, D, E) according to the initial weight (26.4, 31.89, 36.38, 41.09, 46.91) gm, the birds were reared in a wooden cage consist of individual compartments with dimensions (30×30×40) cm, The feed and water was available adlibitum, The birds and feed weighted weekly by sensitive balance. The result shows that initial weight had a significant effect on body weight, weight gain, feed and protein consumption, and growth rate but not significant on feed and protein conversion, where group E showed the best results, The relationship between initial body weight and productive traits were studied and the prediction equation of productive traits depending on initial weight shows highly significant

Rafea mohammedtaher khulel

A huge number of embedded devices offer their services to the end users in pervasive environments. Context-aware discovery is a rich and very dynamic system extensively applied for combining the different mobile devices, sensors, actuators and software functions. Existing knowledge-based system using the Common KADS (CKADS) system represent contextual information but algorithm are not effective in predicting the user behavior. Current Location-aware Private Service Discovery (LPSD) considers the discovery path for reducing the distributed topology and flooding operations. LPSD in pervasive environment is not effective in accurately locating the required service by searching method. To present an architecture principle for accurately predicting the user behavior in mobile-pervasive computing environment, Affluent Context Aware Systems based on the User Behavior (ACAS-UB) is proposed in this paper. ACAS-UB mechanism contains the class of mobile devices that can sense (i.e.,) search the physical pervasive environment. Affluent means effectively engaged mobile devices in ACAS-UB mechanism which uses the context information. The ACAS-UB context information contains the judgment of the similar users and also the response from the other users for improving the effectiveness in pervasive environment user behavior prediction. Master-slave concept is used in the ACAS-UB mechanism for the easy collection of response information from the different users. ACAS-UB mechanism construct the user profile initially from the context information, then performs the similarity measure and finally work is to predict the user behavior. ACAS-UB mechanism provides the hints which are necessary to explore different options, rather than just limiting the options in mobile-pervasive computing environment. ACASUB mechanism is experimented on the factors such as message overhead in pervasive environment, scalability and approximately 10 % lesser processing time.

Dr h shaheen

We reported a case of cyclophosphamide (CYP)-induced posterior reversible encephalopathy syndrome (PRES) in a 26-year-old previously healthy male patient who was presented to the emergency department with a history of fever, shortness of breath, and hemoptysis. After extensive investigations, including bronchoscopy and autoimmune screening, he was diagnosed with renalpulmonary syndrome. The diagnosis of CYP-related PRES was based on the development of neurological clinical picture supported by magnetic resonance imaging findings. The dose of CYP was decreased to 75 mg/day, and the patient’s symptoms improved after 3 days.

Karishma

A study of knowledge seeking behaviour of users is essential for evolving suitable guidelines for knowledge organisation and processing. The features of knowledge organisation and its use in problem-solving and decision-making are explained. Classification plays an important role in knowledge organisation. An understanding of mental models and mental maps helps in information needs of users effectively. The schemes classification in knowledge processing is highlighted. The paper examines the scope of knowledge organisation in the modern technology and its application.

Subhash reddy b

The use of spectroscopic analysis, particularly UV spectrophotometer, is a simple and essential technique for bulk drug estimation, formulation studies, and compatibility assessments of drugs with various excipients. In the pharmaceutical industry, various analytical instruments, including Fourier transform infrared spectroscopy (FTIR), are employed for investigating drug-excipient interactions that can impact the stability of active pharmaceutical ingredients. This study aimed to develop a UV spectrophotometric method for the analysis of Pioglitazone hydrochloride in phosphate buffer (pH 7.4) and methanolic solution, assessing its linearity and compliance with Beer's Law. Furthermore, we aimed to use FTIR to characterize potential interactions between Pioglitazone and common pharmaceutical excipients, such as Guar Gum, Chitosan, and Sodium Alginate. Standard solutions of Pioglitazone were prepared in phosphate buffer (pH 7.4) and methanol. UV spectrophotometer was conducted to determine the maximum absorption wavelength. Calibration curves were constructed to evaluate linearity and adherence to Beer's Law. FTIR analyses were performed to investigate drug-excipient interactions by examining the functional groups. In phosphate buffer (pH 7.4), the maximum absorption wavelength for Pioglitazone hydrochloride was 268 nm. The calibration curve for Pioglitazone in phosphate buffer (pH 7.4) demonstrated linearity in the concentration range of 1–20 μg/ml, with a correlation coefficient of 0.998. In methanol, the maximum absorption wavelength for Pioglitazone hydrochloride was found to be 272 nm. The calibration curve in methanol exhibited linearity in the range of 1–20 μg/ml, with a correlation coefficient of 0.999. FTIR analysis revealed potential drug-excipient interactions, particularly in the case of Guar Gum, Chitosan, and Sodium Alginate, suggesting the formation of stable hydrogen bonds. The developed UV spectrophotometric method for Pioglitazone analysis is a reliable, cost- effective, and reproducible approach, making it a valuable tool for drug development and quality control. Additionally, the FTIR characterization confirmed interactions between Pioglitazone and common pharmaceutical excipients, enhancing our understanding of formulation compatibility,

Archana mehrotra

This paper investigated the variation in the multidimensional competencies and professional development needs of kindergarten teachers using a cross-sectional research design. It involved 54 purposively selected kindergarten teachers and collected the data using the self-assessment tool adopted by the Department of Education from the National Research Center for Teacher Quality in the Philippines. These data were analyzed using both descriptive and inferential statistics. As found, kindergarten teachers have a high level of competencies across dimensions. Also, they have a very high extent of professional development needs in content knowledge and pedagogy and the learning environment and diversity of learners. Moreover, they have a high extent of professional needs in two dimensions. The reported high priorities for training imply more emphasis on providing them professional development activities. Results found no significant difference in the competencies of kindergarten teachers in terms of age, position, civil status, degree, and years of teaching. On the contrary, significant differences revealed in their competencies in content knowledge and pedagogy, learning environment and learners’ diversity, and curriculum and planning between those with masters and without a master’s degree. Lastly, results show no significant difference in their professional development needs. These results have implications for future research and planning for a more responsive and cost-effective professional development initiatives in the locale.

Manuel caingcoy

Cardiovascular diseases represent a formidable global health challenge, standing as the foremost cause of both mortality and morbidity. Atherosclerosis and myocardial infarction, as primary contributors to this epidemiological burden, underscore the urgent need for effective therapeutic interventions with minimal side effects. Natural compounds derived from plants have emerged as promising candidates, given their enhanced efficacy and reduced adverse effects. Phytochemicals, in particular, have garnered attention for their potential as alternative therapeutic agents. This review delves into the cardioprotective potential of pinocembrin (5,7-Dihydroxy flavanone), a compound extracted from various plants and honey. Renowned for its antioxidant and anti-inflammatory properties, pinocembrin demonstrates significant cardioprotective effects through the modulation of diverse signaling pathways. Atherosclerosis and myocardial infarction entail intricate cellular mechanisms involving oxidative stress, inflammatory responses, cellular remodeling, and programmed cell death. Pinocembrin, by targeting key factors within these pathways, exhibits cardioprotective actions. While existing research underscores its effectiveness, further investigations are warranted to elucidate the impact of pinocembrin on additional cardiovascular conditions and explore novel molecular targets, thus paving the way for future advancements in therapeutic interventions.

Brinda elangovan

A mobile adhoc network is a Self-configuring network of mobile routers connected by wireless links. In the mobile adhoc network, each and every device moves independently in any direction so that there are frequent changes in the links. It is essential to learn the position of the neighbors because there is increase in location-aware services. So, there is a chance that the malicious nodes are easily abused the process. The significant problem in mobile networks is correctness of node locations and also it is primarily challenging in the presence of adversaries. So, the neighbor position verification protocol is used to a fully distributed, a lightweight NPV procedure which allows each node to obtain the locations advertised by its neighbors and asses their truthfulness. Further to extend neighbor position verification protocols in the proactive model that need to each node constantly verify the position of its neighbors. So, we introduce a technique called secure link state updating which provides secure proactive topology discovery that is multiply useful for the network operation. This technique is vigorous against individual attackers, it is capable to adjust its capacity between local and network-wide topology discovery, and also operating in networks of frequently changing topology and membership nodes. Experimental results show that the proposed system is high efficiency in terms of security when compared to the existing system.

Dr h shaheen

The present study was designed to evaluate the In vitro anti-oxidant cardio-protective activity of Hydro alcoholic bark extract of Terminalia paniculata Roxb on Isoproterenol induced Myocardial Infarction in Rat. Wistar albino rats used in this experiment were pretreated with vehicle, HAETP (200,400 and 600 mg/kg, p.o), Vit-C (20 mg/kg, p.o) for 14 days, on 14th and 15th day, Isoproterenol (85 mg/kg, s.c) was injected. After 24 h of last dose of ISO administration, ECG was recorded and serum biomarkers CK-MB, LDH, SGOT and SGPT were estimated. Further antioxidant levels were estimated from the tissue homogenates. Finally histopathological examination of heart was performed. HAETP have shown significant antioxidant activity in DPPH and reducing power methods. Moreover pretreatment with HAETP and Vit C improved ECG pattern and histopathology of heart.

Bm v swamy

With the expansion of human societies, extending up to almost every corner of the earth, transforming it to be as per their condition, humankind has proved their extraordinary dominance on the earth. The dominating attitude of humans has not resulted pleasantly every time. Poverty is one such curse that has shamed the progressing world community. Christianity has dedicated a large portion of its ministerial approach towards the underprivileged. This paper presents a missiological approach to uplift the slum dwellers in the city of Pune with education and health reforms. A similar project was experimented in 2014 among homeless people. The project did well and the results were significantly progressive and potential. It is assumed that this paper will bring an insightful approach that benefits the slums in Pune and enhance the “serving the humanity” aspect of the Christian mission.

Santosh kumar

Background: Cannabis sativa has garnered significant attention due to its complex phytochemistry and diverse pharmacological properties. Given the rising interest in medicinal cannabis, understanding its physicochemical properties is crucial for drug development, quality control, and abuse prevention. This study aimed to analyze its phytoconstituents, with a focus on the isolation and profiling of cannabinoids. Methods: Fresh C. sativa leaves were macerated in ethanol to obtain a crude extract, which underwent phytochemical screening to detect alkaloids, flavonoids, cardiac glycosides, terpenes, steroids, and resins. Thin-layer chromatography (TLC) was performed using a n-hexane/diethyl ether (8:2) ratio as the mobile phase to separate cannabinoids, with visualization under UV light. Column chromatography further purified the extract, and subsequent TLC confirmed cannabinoid-rich fractions. Hydrogen peroxide-modified TLC was employed to assess oxidation effects on cannabinoid stability. Results: Phytochemical screening confirmed the presence of alkaloids, flavonoids, terpenes, and resins, while saponins and tannins were absent. TLC analysis revealed distinct Rf values for tetrahydrocannabinol (THC = 0.94) and cannabidiol (CBD = 0.90), with color differentiation indicating successful separation and a more polar nature of CBD. Column chromatography yielded enriched fractions, validated by TLC. Hydrogen peroxide exposure altered Rf values of 0.78 to 0.8, suggesting oxidative degradation. The study identified THC and CBD as dominant markers, alongside minor cannabinoids, reinforcing C. sativa’s complex chemical profile. These findings give clues to further research into standardized extraction protocols and stability testing to optimize medicinal applications of the plant and its phytoconstituents. Conclusions: This study highlights the efficacy of TLC and column chromatography for cannabinoid isolation and profiling. The presence of THC, CBD, and other bioactive compounds underscores C. sativa’s dual therapeutic and psychoactive potential.

Karishma

Tuberculosis is communicable disease which is common and often deadly infectious disease caused by mycobacterium tuberculosis. Tuberculosis continues to be a major public health problem in the world. The aim of this study is to assess prevalence and associated risk factors of pulmonary tuberculosis. Treatment and development of multidrug-resistant tuberculosis were also considered. Drugs for Pulmonary tuberculosis confirmed cases used in calculating tuberculosis prevalence in Libya which is obtained from archive department of Abu Seta Hospital. Data obtained from 427 files during 2019 determine the incidence and epidemiology of tuberculosis in Libya. For a total of 427 confirmed cases of pulmonary tuberculosis, about 75.0% of the cases were male and most of the patients (55.0%) were within the age group of 20 - 40 years old. Of the study patients, 114 patients (26.7%) were viral infected and most of the viral infected cases were in the age group of 20 - 40 years and the majority of this age group patients (n = 41, 53.2%) were infected with HIV/HCV, while the least percentage in this group age were infected with HIV/HBsAg (01.3%). Among 427 cases, 73 cases (17.1%) were comorbid with other chronic diseases. Of the 73 cases, 54 cases (74.0%) were diabetes mellitus whereas only 1.4% of them had bronchial asthma, Parkinsonism and renal failure. The drug therapy of active tuberculosis disease needs combination chemotherapy to escape the selection of naturally occurring drug-resistant mutants. Amongst current anti tuberculosis drugs, the rifamycins hold the highest potential for shortening treatment and improving effects. Prevalence of smear positive tuberculosis and bacteriologically confirmed that a high rate of tuberculosis among unemployed population. This study reported that the highest incidence rate is found in people who are smokers.

Mediterranean journal of pharmacy and pharmaceutical sciences

Information and communication technology is an instrument in addressing some of the issues of Indian higher education however; there are certain drawbacks to using ICT to enhance teaching and learning. The present research was carried out in The Maharaja Sayajirao University to study the impediment faced by them in the use of ICT in their professional work. Quantitative data was collected from two hundred and ninety faculty members through the purposive and convenient sampling method. The data indicate that faculty members faced technological infrastructure-related impediments such as lack of smart boards, lack of computers, uneven bandwidth of internet, slow internet connection. It is suggested that an adequate atmosphere be developed in the institution that would encourage faculty members to use ICT.

Maniar avani

Background: Exhaust noise is known to be a major pollutant in the environment and workplaces due to the development of industry and transportation. Exhaust noise can be reduced to normal levels by mufflers or silencers. A reactive muffler efficiently dampens noise at low frequencies by reflecting sound waves. Therefore, muffler design is of great importance in exhaust noise reduction. Transmission loss (TL) is an essential characteristic of mufflers, demonstrating their acoustical properties. Any acoustical appliance is selected based on its damping performance and reliability. Predicting TL through experimentation is different from theoretical calculations. Methods: In the present study, a double-expansion chamber muffler was designed as a reflective muffler on a laboratory scale by equations. Next, TL was evaluated by an impedance tube applying a 4-microphone technique to determine the acoustical performance of the designed muffler. Results: Findings revealed that the TL of the muffler at 312 Hz frequency obtained 27.5 dB agreement with the required TL of the muffler of 25 dB. In addition, the TL of the muffler against frequency attenuates noise in broadband frequencies. Conclusions: These results indicated that the built muffler provides desired TL for exhaust chambers. Therefore, equations can be used as a precise method for muffler design. Furthermore, multi-expansion chamber mufflers are useful for reducing noise at a wide range of frequencies.

Niloofar