The growing study of foreign policy change offers various explanations of change and continuity in foreign policy. By focusing on the actors of foreign policy decision-making, past scholarship has mainly concentrated on the role of institutional and noninstitutional factors in foreign policy change. However, decentralized decision-making is more relevant to democratic regimes than authoritarian regimes. Despite the abundance of case studies on foreign policy making in nondemocracies, advancements in the conceptual understanding of foreign policy change in authoritarian regimes are still needed. Addressing Uzbekistan’s foreign policy, this article proposes an advanced framework to explain why and how foreign policy change takes place under authoritarian leaders. A leader’s perception of the external environment is argued to be a decisive factor inducing authoritarian leaders to (re)consider their regime survival strategy. Concern with regime survival, in turn, shapes foreign policy goals which are manifested in distinctive foreign policy behavior of a leader. Ultimately, the behavior of a leader translates into certain foreign policy outcomes.

Feruza madaminova

Pets need special care and tracking system to track their path in case of lost. Due to our busy life style, this task is not simple as it used to be. The aim of this work is to design and implement smart pet house and tracking system. The objective of this paper is to allow pets owners to automate simple things like monitoring and tracking of the path of pets. Also lighting, feeding and air-conditioning controls. The proposed work addresses the implementation and analysis of a wireless sensor networks based pet location monitoring system for domestic scenarios. These systems describes, finding the path of lost pet using fitbit flex scale device and also using GPS tracker. Pet begin moving before you get a GPS signal, the tracker will calculate distance using steps and stride length as described above until a GPS signal is found.

Dr h shaheen

The chosen organisation for this research work is Primark. Primark is a renowned fashion retailer operating in the global markets today. The organisation is known for its latest fashion products (Azad, 2018). Primark has been selected because it is a famous brand in the global market and has an okay -developed marketing department. Marketing is one of the most critical areas of an organisation. This is mainly because this area helps plan and implement strategies that can enhance an organisation’s sales, profits, and market share. Moreover, marketing can also ensure that customer satisfaction is high, and the positive relationships are maintained with all individuals and parties that are directly or indirectly associated with an organisation. The marketing mix of an organisation comprises of several strategies that can enhance the value to its customers. Following tasks will further elaborate about marketing and its core concepts -

Zamzam abdelazim

Diabetes mellitus is a common and chronic metabolic disorder. Uncontrolled diabetes mellitus leads to body organ damage if not treated properly. Educational intervention is necessary from health-care providers such as pharmacists to prevent or reduce organ damage and complications among the diabetic patients. Several studies have demonstrated the contribution of pharmacists in achieving a better control of diabetes mellitus. Thus, this study intended to assess the knowledge and practice regarding foot care among Libyan diabetic patients in Al-Bayda city. In addition, to determine the association between knowledge and practice regarding diabetic foot care with selected demographic variables. This is a cross sectional study conducted at Diabetes Center Aljabal Al akhdar in Al-Bayda between April and August, 2022. A total of 400 participants with diabetes were enrolled and interviewed by using a self-design questionnaire for knowledge and practice of foot care after taking verbal agreement. Data was analyzed by using SPSS software version 26.0. In this study, 191 subjects were male (47.8%) and 209 subjects (52.3%) were female. On the topic of foot care, 51.8% of the participants stated they did know how to perform correct foot hygiene and 33.5% stated that drying should consist of passing a towel between their toes. Female subjects statistically had more knowledge than male subjects on the right footwear and correct way of nail cutting (p < 0.01 and p < 0.001, respectively). In relation to practice, the frequency of patients with a good practice was 126 (31.5%) and with poor practice was 274 (68.5%). Evaluating the parameters dry, moisturize and nail cutting, women showed a significant difference in relation to men, with a high significance level in the three parameters. In conclusion, the knowledge and practice of foot care in Libyan patients with diabetes were poor. So, an educational program is recommended to improve the awareness of foot care. Diabetic patients should be provided information about self-care of their feet by health care providers such as pharmacists to prevent and delay onset of foot complications and improve the quality of life.

Mediterranean journal of pharmacy and pharmaceutical sciences

Cet article porte sur l’ouvrage Le ventre, le pain ou la cendre de Tchicaya U Tam’si. À partir des approches linguistique, stylistique et sémiotique, nous avons tenté de montrer, dans notre analyse, en quoi l’écriture de ce recueil construit des stratégies discursives propres à retenir l’attention du récepteur. À cet effet, nous avons relevé deux principales figures de rhétoriques à savoir, l’emphase et l’hyperbole. Ces deux procédés de style produisent d’une part un effet d’insistance du procès poétique ; et de l’autre, un effet d’amplification du langage poétique.

Assanvo

Considering the site (habitat) specific variations in the metabolic activities in the freshwater bivalves, we reported here the changes in the rate of oxygen consumption, rate of ammonia excretion and O: N ratio in the freshwater bivalve mollusc, Lamellidens marginalis (Lamark) from lotic and lentic water habitats on April-May during summer season. The adult freshwater bivalves, Lamellidens marginalis (82-84 mm shell length) from lotic and lentic water near Jayakwadi dam on Godavari river was selected for determination of rate of oxygen consumption, rate of ammonia excretion and O: N ratio. The adult bivalves from lotic water habitat showed high rate of oxygen consumption and low rate of ammonia excretion. The O: N ratio showed higher values in bivalves collected from lotic water than lentic water during summer season. The results of study are discussed in the light of possible physiological processes in freshwater bivalve molluscs.

Dr. pritesh ramanlal gugale

Inflammation is a natural aspect of the immune system's response. Pain, redness, heat or warmth, and swelling are the four major symptoms of inflammation. Plants can generate a vast range of phytochemical substances as secondary metabolites, all of which have anti-inflammatory properties. Herbal medicines are significant cures for the treatment of a variety of disorders around the world. Medicinal plants are made up of roughly 7500 species, with representatives from about 17,000 higher flowering plant species. Even when synthetic chemistry has advanced beyond expectations, the utilization of natural products in the production of medications utilized in modern medicine is unrivalled. Anti-inflammatory medicines can help to reduce tissue damage and improve patient comfort by interfering with the pathophysiology of inflammation. As a result of the huge number of species available for investigation, the effective creation of new naturally occurring anti-inflammatory medications relies mostly on a multidisciplinary approach to finding new compounds. Despite the fact that many review articles have been written in this area, the vast majority of them only looked at the subject from a regional perspective. Various non-steroidal anti-inflammatory medicines have been proven to alleviate pain and inflammation by inhibiting the isoform of cyclooxygenase enzyme's digestion of arachidonic acid, hence lowering prostaglandin synthesis. Non-steroidal anti-inflammatory medicines come with a slew of negative side effects. Thus, there are, however, medicinal herbs that have anti-inflammatory therapeutic properties with a little or no negative side effects.

Mediterranean journal of pharmacy and pharmaceutical sciences

Radio resource allocation in VCN is a challenging role in an intelligent transportation system due to traffic congestion. Lot of time is wasted because of traffic congestion. Due to traffic congestion, user has to miss their important work. In this paper, we propose radio resource allocation scheme so that user can utilize their time by taking the advantage of subscription plan. In this scenario, multitype vehicle identification scheme from real time traffic database is proposed, its history will match in transport database and vehicle travelling history database. Proposed method indicates 95% accuracy for multitype vehicle detection. Subscription plans are allocated to the user on the basis of resource allocation, scheduling, levelling and forecasting. This scheme is better for traffic management, vehicle tracking as well as time management.

Vartika agarwal

The conservation of traditional medicinal knowledge opens the door towards modern aspects of herbal drug discovery. It started with knowledge exchange through ethnic groups through oral tradition and then in the documented form. Herbaria conserving identified and authenticated plants for future correspondence play an important role. In presenting the review, the authors have declared different auxiliary aspects of herbaria for phytomedicinal research.

Dr. salman ahmed

The incorporation of lomustine, a hydrophobic anticancer drug into PLGA nanoparticles by interfacial deposition method was optimized. Based on the optimal parameters, it was found that lomustine-PLGA nanoparticles with acceptable properties could be obtained. Optimization of formulation variables to control the size and drug entrapment efficiency of the prepared nanoparticles seems to be based on the same scientific principles as drug-loaded nanoparticles prepared by nanoprecipitation, solvent evaporation method. The process was the most important factor to control the particle size, while both the drug-polymer interaction and the partition of drug in organic and aqueous phases were the crucial factors to govern the drug entrapment efficiency. PLGA concentration at lower level (100 mg), 1:5 organic phase: aqueous ratio, 1%w/v PVA concentration, 3%w/v pluronic F68 achieved smaller particle size. Additionally, L:G ratio of PLGA 75:25, lower volume of organic solvent (1:10 organic phase: aqueous phase), higher initial drug content (10 mg) enhanced the drug entrapment efficiency and maintained lomustine concentration in blood for an extended time period, elevated lomustine concentration in lungs and slowed the elimination of lomustine. The biodistribution profiles of prepared nanoparticles in albino mice showed higher plasma drug concentration for longer period of time, elevated drug concentration in lungs and slow elimination from kidney. No toxic effects of prepared nanoparticles were observed in histopathological examination of lungs and kidney. The systematic investigation reported here promises the development of PLGA nanoparticles loaded with lomustine when tested in Lung Cancer cell line L132 and toxicological/ histopathological studies in albino mice.

Archana mehrotra

Background Mauritius embraces principles of a welfare state with free health care at point of use in any public facilities. However, the health financing landscape changed in 2007 when Private Health Expenditure (PvtHE) surpassed General Government Health Expenditure. PvtHE is predominately out of pocket (OOP) with only 3.4% related to premiums for private insurance. In 2014, Household OOP Expenditure on health accounted for 52.8% of total health expenditure. OOP is known to be regressive and to impact negatively on households’ living standards. Objectives This paper aims to examine trends in OOP in Mauritius, to assess its impacts through an analysis of key indicators of financial protection, namely catastrophic health expenditure (CHE) and impoverishment due to OOP health expenditure. It also aims to predict core determinants of CHEs. Methods Household Budget Surveys (HBS) of 2001/2002, 2006/2007 and 2012 were the primary source data. CHE and impoverishment were used to assess financial hardships resulting from OOP health payments. The incidence of CHE was estimated at three threshold levels (10,25 and 40%), using the budget share and the capacity to pay approaches. Impoverishment due to OOP was measured by changes in the incidence of poverty and intensity of poverty using the US$ 3.1 international poverty line. Logistic regression analysis was used to identify determinants of CHE. Findings Household CHE increased from 5.78% in 2001/02 to 8.85% in 2012 and 0.61% in 2001/02 to 1.25% in 2012, for 10 and 40% thresholds, respectively. The incidence of CHE was significantly higher in urban areas compared to rural areas. The highest levels of CHEs were among households’ heads, who are retired rising from 1.62% in 2001/02 to 3.71% in 2012, followed by households’ head who are widowed from 2.29% in 2001/02 to 2.63% in 2012 and homemakers from 2.12% in 2001/02 to 2.57% in 2012 at the 40% threshold. The share of households pushed below the poverty line due to OOP dropped from 0.4% in 2001/02 to 0.2% in 2006/07 before rising to 0.34% in 2012. In 2012, poverty gap occurred only among households under poorest quintile 1 (0.24%) and quintile 2 (0.03%). Overall poverty gap dropped from 0.08% in 2001/02 to 0.05% in 2012. Logistic regression analysis revealed that the odds ratio of facing CHE were significant only among households with heads being retired and with a presence of an elderly member in the household. Conclusion Despite the rise in incidence of CHE between 2001 and 2012 the impact of OOP on the level of impoverishment and poverty gap has not been significant.

Ajoy nundoochan

Ethanol and hexane extracts of the leaves and male flowers of Luffa cylindrica were evaluated for antiemetic and anti-inflammatory effects using chick emesis model and carrageenan-induced rat paw oedema. The antiemetic effect was observed at 150 mg/kg body weight, whereas the anti-inflammatory effect was observed at doses of 500,750 and 1000 mg/kg body weight orally. Chlorpromazine 150 mg/kg and indomethacin 10mg/kg orally were used as standard antiemetic and anti-inflammatory drugs. The antiemetic effect was determined by calculating the mean decrease in the number of retching compared to the control group after 10 minutes of copper sulfate (50 mg/kg orally) administration. The degree of paw oedema of all the groups was measured using a plethysmometer at the 5th hour of carrageenan (1% w/v) administration. All extracts except hexane extract of leaves exhibited statistically significant (P<0.001) antiemetic and except hexane extract of flower, all extracts exhibited statistically significant (P<0.05) anti-inflammatory effects.

Dr. salman ahmed

This study examined work-life balance and teacher engagement in private secondary schools in Rivers State. Three research questions and three hypotheses guided the study. The study adopted a correlation research design with a population of 7,143 teachers (2,676 males and 4,467 females) in all the 275 private secondary schools in Rivers State. The sample size of 714 teachers was drawn through a proportionate stratified random sampling technique, which represents 10% of the population. Two self-designed instruments entitled: “Work-life Balance Questionnaire (WLBQ)” and “Teacher Engagement Questionnaire (TEQ)” were used for data collection. The instruments were in two sections –A and B. Section A consisted of the demographic factors while Section B contained the variables that were used to elicit information from the respondents. Section B contained 20 items on Work-life Balance and 15 items on Teacher Engagement respectively. Face and content validities were ensured by experts in the relevant areas. The Cronbach’s Alpha reliability method was used to establish the internal consistency, and indexes of .79 for WLBQ and .83 for TEQ were established respectively. Research questions 1 and 2 were answered using simple regression while research question 3 was answered using multiple regression. Hypotheses 1 and 2 were tested with a t-test associated with simple regression while hypothesis 3 was tested using ANOVA associated with multiple regression at 0.05 alpha level. The findings of the study revealed, among others, that work-life balance significantly and jointly predicted teacher engagement to a very low extent in secondary schools in Rivers State. Based on the findings, it was recommended, among others, that both employers and school managers should create flexible work environments that promote work-life balance for teachers so as to motivate them to perform optimally for the attainment of educational goals.

Fxintegrity publishing

Background Covid-19 pandemic has hit many countries and put the majority of the public health system to test globally. Mandatory use of face mask was among policies set by the government to contain the spread of the novel disease. But citizens’ attitudes and compliance with these policies are important in controlling the pandemic. We assessed gender-based compliance to Covid-19 protocol (use of face mask) in Jos South, Plateau State, Nigeria. Methods Perception regarding Covid-19 and the use of face masks were assessed among participants using a questionnaire-based survey. In a cross-sectional study, ninety (n=90) questionnaires were administered to willing participants directly. A Chi-square test was used to determine the descriptive analysis of all responses, P-values <0.05 were considered statistically significant. Result Out of 90 participants, 55.6% (50/90) were male and 44.4%(40/90) were female. Forty-two (84%) males deny the existence of the pandemic while in females, 14 (35%) deny that Covid-19 exist. Thirty-seven (74%) of the male respondents do not comply with to use of the face mask and use a single face mask multiple times without decontamination. In females, 28 (70%) comply with the use of the face mask. Unlike the men, 20 (50%) of the females always decontaminate the face mask. The middle-aged adult (26-45 years) uses the face mask more than the young (18-25 years). There was a significant association of gender in relation to the perception of Covid-19 and the use of facemask (p< 0.05). Conclusion Male respondents showed an irresponsible attitude complying to Covid-19 protocol than the females, therefore, enlisting them as a risk factor for the continued spread of the virus. We recommend that public health awareness and campaigns should focus and employ greater influence on men and young adults in their compliance with the preventive protocols.

Bitrus inuwa

Penelitian ini dilatar belakangi oleh adanya permasalahan yang terjadi pada MIN Bangka Belitung Pontianak seperti guru kurang melibatkan siswa dalam materi pembelajaran, guru cenderung menyampaikan materi dengan menggunakan metode ceramah tanpa adanya variasi sehingga menyebabkan kejenuhan dalam belajar, guru kurang memahami dalam tentang memilih dan menentukan strategi cooperative learning tife jigsawyang tepat sehingga berdampak pada terciptanya proses pembelajara yang lebih baik. Penelitian bertujuan untukmengetahui: perencanaan, langkah-langkah, dan evaluasi dalam pembelajaran Materi Aqidah dengan Strategi Cooperative Tipe Jigsaw dalam pembelajaran Akidah Akhlak Materi Sikap pada guru di Kelas V MIN Bangka Belitung Pontianak Tahun Pelajaran 2017/2018. Hasil penelitian ini dapat disimpulkan bahwa Perencanaan Strategi Cooperative Learning Tipe Jigsawdalam Pembelajaran Akidah Akhlak Pada Materi Akhlak Tercela di Kelas V MIN Bangka Belitung Pontianak dengan lebih baik dan siswa lebih aktif dalam proses pembelajaran; langkah-langkah strategi cooperative learning tipe jigsaw dalam materi sikap siswa di sekolahdi kelas V MIN dibagi menjadi 5 kelompok, setiap kelompok diksih materi pembelajaran, dan siswa mendiskusikan dengan materi tersebut; Pelaksanaan evaluasi proses dan hasil kegiatan pembelajaran yang menggunakan langkah strategi cooperative learning tipe jigsaw dalam materi sikap siswa di sekolahdi kelas V MIN Negeri Bangka Belitung Pontianak adalah menggunakan tes tertulis dan tes lisan juga mengunakan penilain proses dari observasi siswa saat proses pembelajaran atau setelah mata kuliah selesai.

Educare: journal of primary education

This book presents more than 600 eye-catching structural geological photographs and explanatory descriptions, from different Indian terrains. This book will enable easy identification of deformation features, one of the most important tasks in structural geology at the meso- and micro-scales.

Rajkumar ghosh

This Experiment was conducted on 120 day old unsexed Ross broiler chicks to study the effect of added methionine to soybean meal as substitute for protein concentrate in the starter ration on some productive traits . The chicks were raised on floor were distributed to three treatments with four replicates each ( 10 birds) . The three experimental starter rations (1-28) day contained 2800 kcal/kg ME and 22% cp . The first supplemented with 5% protein concentrate , while the second and third were with out protein concentrate but supplemented with 0.1 and 0.2% methionine respectively . The Finisher ration (29-49) day contained 3047 kcal/kg ME and 19.19% cp. At 49 day of age 2 birds from each replicate were slaughtered for carcass traits . Statistic analysis of data showed a significant increase (P ≤ 0.05) in body weight , weight gain , feed and protein efficiency ratio for third treatment during (1-28) day , No significant difference in all studied traits during (29-49)day, and the third treatment showed best economic efficiency .

Rafea mohammedtaher khulel

This study investigated the level of environmental citizenship development through curriculum development planning among primary school pupils in Rivers State. Three research questions and two hypotheses guided the study. The descriptive survey design was used. The population for the study was the 15,611 teachers in the 962 public primary schools in Rivers State. A stratified random sampling technique was used to draw a sample of 1,600 teachers which represents 10.2% of the population. A researchers’ designed questionnaire titled "Curriculum Development Planning in Environmental Education Questionnaire" was the instrument used for the study. The instruments were validated by three experts. Reliability coefficients of 0.88 (Curriculum Provision), 0.73 (Environmental Education Projects), and 0.79 (Challenges) were derived using Cronbach alpha. Mean and standard deviation was used to answer the research questions while the hypotheses were tested using the z-test. Findings revealed that the extent to which environmental education projects were utilized to develop environmental citizenship in pupils is low. The challenges militating against the teaching of environmental education are lack of commitment from the school management, lack of time in the lesson timetable to integrate environmental education contents in other subject areas, and teachers' inadequate knowledge of environmental education integration techniques. It was recommended amongst others that the Nigerian Education Research and Development Council should design age-appropriate curriculum contents/topics that can be integrated into various subjects.

Fxintegrity publishing

A burning sensation on eating spicy foods purportedly supports the role of capsaicin, an active component of chili peppers, in the etiology of oral submucous fibrosis (OSF). Although the mast cell mediators and activated P2X receptors induce a constant burning sensation through an ATP-dependent mechanism, it is the activation of the transient receptor potential vanilloid 1 (TRPV-1) receptor by capsaicin that aggravates it. The molecular basis for the burning pain in OSF is thus attributable to the activation of TRPV1. There is overwhelming evidence that confirms capsaicin has more of a protective role in attenuating fibrosis and is potentially therapeutic in reversing conditions linked to collagen accumulation. The activation of TRPV-1 by capsaicin increases intracellular calcium ([Ca2+]i), upregulates AMP-activated protein kinase (AMPK) and Sirtuin-1 (SIRT-1), to enrich endothelium-dependent vasodilation via endothelial nitric oxide synthase (eNOS). The induction of vasodilation induces antifibrotic effects by alleviating hypoxia. The antifibrotic effects of capsaicin are mediated through the upregulation of antioxidant enzymes, downregulation of inflammatory genes and suppression of new collagen fibril formation. Capsaicin also demonstrates an anticarcinogenic effect by upregulating the cytotoxic T cells and downregulating regulatory T cells through the inhibition of angiogenesis and promotion of apoptosis. Judicious administration of capsaicin with an appropriate delivery mechanism may have therapeutic benefits in reducing pain sensation, rendering antifibrotic effects, and preventing the malignant transformation of OSF. This paper provides an overview of the molecular basis of capsaicin and its therapeutic application as an antifibrotic and anticarcinogenic agent for the treatment of OSF

Mohit sharma

Natural products the most significant source for pharmaceutical development have been investigated and utilized to alleviate diseases since early human history. Natural compounds from both terrestrial and marine organisms have been extensively used for the treatment of many diseases either in their natural form or as a template for synthetic modification. A variety of new chemical entities from natural resources at present are undergoing clinical trials. The government sector, industries and academic institutions also play an important role in the natural drug development for human health enhancement.

Dr. salman ahmed