Influenza A virus presents a significant public health burden worldwide, with the 1918 Spanish flu pandemic being the most dramatic example. Swine influenza viruses can be transmitted to humans through occupational exposures and in live pig markets. Novel variants can emerge in pigs because they can be infected by human, avian and swine strains. This study was carried out to determine the seroprevalence and serotypes of swine influenza in pigs from a major slaughter slab in southern Kaduna. Using competitive ELISA and haemagglutination-inhibition (HI) assays, 305 swine sera were analysed. The result showed an overall seroprevalence of 28.20% (n=86), with H3N2 7.87% (n=24) emerging as the most dominant subtype in circulation. Concurrent antibody detection of H1N1 in 5.26% (n=16) was also detected in boar 2.62% (n=8) and sows 2.62% (n=8). This study revealed swine Influenza H1N1 and H3N2 serotypes are in circulation in pigs in Kaduna State, and that reassortment in the instance of co-infection of swine host is possible.

Bitrus inuwa

Cardiovascular diseases represent a formidable global health challenge, standing as the foremost cause of both mortality and morbidity. Atherosclerosis and myocardial infarction, as primary contributors to this epidemiological burden, underscore the urgent need for effective therapeutic interventions with minimal side effects. Natural compounds derived from plants have emerged as promising candidates, given their enhanced efficacy and reduced adverse effects. Phytochemicals, in particular, have garnered attention for their potential as alternative therapeutic agents. This review delves into the cardioprotective potential of pinocembrin (5,7-Dihydroxy flavanone), a compound extracted from various plants and honey. Renowned for its antioxidant and anti-inflammatory properties, pinocembrin demonstrates significant cardioprotective effects through the modulation of diverse signaling pathways. Atherosclerosis and myocardial infarction entail intricate cellular mechanisms involving oxidative stress, inflammatory responses, cellular remodeling, and programmed cell death. Pinocembrin, by targeting key factors within these pathways, exhibits cardioprotective actions. While existing research underscores its effectiveness, further investigations are warranted to elucidate the impact of pinocembrin on additional cardiovascular conditions and explore novel molecular targets, thus paving the way for future advancements in therapeutic interventions.

Brinda elangovan

Dignity therapy (DT) is an evidence-based psychotherapeutic approach originally designed to alleviate emotional and existential distress in patients with terminal illnesses. While dignity therapy has been well documented in palliative care, emerging perspectives suggest that its principles such as promoting autonomy, meaning, and self-worth can be beneficial for persons with severe mental illness (SMI) who often experience stigma, identity loss, and existential suffering. Although severe mental illness and terminal illness are distinct conditions both may involve the profound psychological and existential challenges that affect personal dignity. This paper explores the philosophical foundations and therapeutic benefits of dignity therapy, with a particular focus on its potential application in mental health settings. It highlights the significance of preserving dignity in psychiatric care and emphasizes the need for compassionate, personcentered mental health support tailored to the lived experiences of the person with severe mental illness.

Karishma

The study identified the pragmatic competence level of the second language (L2) learners through Written Discourse Completion Test (WDCT) administered to purposively selected 40 first-year education students. A modified questionnaire based on Survey for Academic English Language Exposure (SAELE) was used to determine the effectiveness of academic English language exposure on the pragmatic competence development of the respondents. The study employed the descriptive-correlational method, while various statistical tools were utilized to analyze and interpret the data. Weighted mean was used to determine the respondents’ pragmatic competence level and the effectiveness of academic English language exposure on the pragmatic competence development of the respondents. Moreover, Pearson Product Moment Correlation (PPMC) was employed to determine the significant relationship between the two variables. Results in WDCT showed that the average scores in the pre-test and post-test results fall under the competent level. Meanwhile, the effectiveness of academic English language exposure on the pragmatic competence development of the respondents was 0.207, which is ineffective. Lastly, the statistical correlation of the two variables showed no significant relationship between them (r=0.046, p>0.05). Based on the study’s results, pedagogical implications for pragmatic and L2 teaching and learning were conceptualized.

Darrel ocampo

This study was aimed to develop lomustine loaded chitosan nanoparticles using a homogenization and spray drying technique. Effect of crosslinking agents (sodium tripolyphosphate (TPP), and sodium hexametaphosphate (HMP)) were studied on the leaching of drug, water uptake of hydrogels, drug release from matrix and its mechanism. Nanoparticles were obtained in the average size range of 111±16.2 to 942±11.7 nm with polydispersity index (PDI) from 0.116±0.039 to 0.517±0.037. Zeta potential of nanoparticles was ranged from 29.0±1.1 to 56.0±1.1 mV. The % encapsulation effi ciency of nanoparticles ranged between 58±0.88% and 96±0.51%.nanoparticles were coated with PEG 6000 to modulate drug release. Swelling index of chitosan-TPP and chitosan-TPP-PEG nanoparticles was about 428% and 350% over the 4 h and it was more (about 465% and 395%) for chitosan-HMP and chitosan-HMP-PEG nanoparticles. Drug release was sustained and diffusion controlled. Optimized formulation was tested for anticancer activity and drug retention study. Cytotoxicity on human lung cancer cell line L132 was studied by trypan blue dye exclusion test. Drug loaded nanoparticles killed L132 cells more effi ciently than the corresponding drug alone (p< 0.05). Due to the increased surface area lomustine loaded TPP and HMP crosslinked chitosan nanoparticles showed better anticancer activity.

Archana mehrotra

The main focus of this study is the coverage of New Straits Times (NST) of the first Palestinian General Elections for two presidential candidates namely, Yasser Arafat and Samiha Khalil. This study aimed to explore if any of Entman’s 1993 framing functions was used in the coverage of this issue and to explore whether the tone of NST coverage was negative, positive, balanced or neutral. To achieve the aims of this study, qualitative content analysis of elections stories from NST has been adopted. The number of news stories was eight, and the time frame started from 19th January to 13th February 1996, where three of these stories were published on the same day of 22nd January, two days after holding the elections on 20th January. Defining problems and diagnosing causes were the most prominent of Entman’s four framing functions presented in all the articles. The moral judgment function was included in four news stories, and suggesting remedies was included in two news stories out of eight. The findings revealed that Yasser Arafat received 50% balanced coverage, followed by 37.5% positive coverage, and only 12.5% negative coverage, while Samiha Khalil received 67% balanced coverage, compared to 33% positive coverage.

Mohammed fadel arandas

Herbal products are being paid particular attention by people around the world since they are natural, effective, and without side effects. In modern medicine, some drugs prescribed to the patients are derived from medicinal plants. Thus, the aim of this study is to investigate the central nervous effects of methanol extract of Ephedra altissima stems, in Albino mice. Doses of 500, 1500, and 3000 mg/kg of the methanol extract were administered in sub-acute doses (three doses), intraperitoneally at 24, 5.0, and 1.0 hours before scoring. General locomotor behavior profile, antidepressant activity, and anxiolytic activity were studied. The results revealed that the methanol extract of Ephedra altissima at 500, 1500, and 3000 mg/kg produced central nervous system depression, a remarkable decrease in the immobility time (forced swimming maze test), no anxiolytic-like effect by using elevated plus-maze model of anxiety. These results suggest that methanol extract of Ephedra altissima exhibits a central depressant activity, antidepressant-like activity, and mild antipsychotic activity without anxiolytic-like effect in tested experimental animal models with the doses used. Therefore, it can be concluded that Ephedra altissima extract may have a central depression, antidepressant-like activity with no effect as anxiolytic-like mood.

Mediterranean journal of pharmacy and pharmaceutical sciences

Customer satisfaction and profit making are the two motives that define software quality; therefore, software industry uses new technologies like component-based software engineering, re-engineering, etc., to make their software production more profitable. The proposed mathematical model is executed under ISO/IEC 9126 quality assurance model and justifies the definition of software quality given by IEEE 1061(1998). The model calculates the degree of stakeholder satisfaction (Q) by combining the quality attributes and it is validated using Shuffled Frog-Leaping Algorithm (SFLA) which improved the result by 2.46%

Dr deepak panwar

Melioidosis is an infection that causes high morbidity and mortality. Predisposing risk factors include diabetes mellitus (DM) and immunocompromised state. We report a case of septic shock secondary to bacteremia caused by Burkholderia pseudomallei in a patient who is supposed to be previously healthy and subsequently diagnosed with DM and glucose-6-phosphate dehydrogenase (G6PD) deficiency. He completed 17 days of intravenous antibiotics followed by a 12-week course of oral trimethoprim/sulfamethoxazole. We postulate that G6PD deficiency could be a risk factor for melioidosis.

Karishma

Effective project management requires an understanding of how stakeholders are impacted by project failure. It draws attention to the effects on those involve finances, reputations, and emotions, assisting organizations in risk avoidance and fostering stakeholder satisfaction, trust, and long-term success. The purpose of this study is to provide proactive risk management, stakeholder involvement, and project result strategies. In order to compile this study, we have used a number literature reviews ranging from 2004 to 2023. The study's findings show that project failure results in significant financial losses, harms reputation, has legal ramifications, affects employee wellbeing, stifles relationships with stakeholders, stifles innovation, and endangers communities and the environment. By Adopting proactive risk management, strong governance, open communication, employee support, stakeholder involvement, strategic resource allocation, and social and environmental responsibility to reduce these negative effects and achieve sustainable project outcomes. The policymakers, practitioners and academia should focus risk factors those are associated with the project failure and hance manage a good harmony among the stakeholders.

Nazim ullah

Efforts to understand the causes of poverty, how poverty is perceived have become important in the fight to mitigate poverty. In Vietnam, studies on the attitudes of poverty in specific populations, such as Vietnamese students, are rare. Thus, this dataset reports the results collected from 180 social work students and non-social work students of Ho Chi Minh City Open University through attitudes toward poverty and poor people in Vietnam. The Attitude toward Poverty Short Form 21-item scale, developed by Yun & Weaver, was used for the data collection. The survey results showed that when looking for causes of poverty, social work students and non-social work students put the most emphasis on structural factors of poverty. However, social work students, compared with non-social work students, consider personal deficiency and stigma more important. In future, this dataset can serve as a reference source for comparative studies on student’ attitudes toward poverty and impoverished persons and for social work education

Le minh tien

Melilotus officinalis (L.) Pallas. is used traditionally to treat hypertension and chronic venous insufficiency. The high prevalence of hypertension and the side effects of antihypertensive drugs potentiate us to evaluate Melilotus officinalis. The hypotensive effect of Melilotus officinalis butanol fraction (MOBF) was investigated in anaesthetised normotensive rats. The doses of 60, 80 and 100 mg/ kg, i.v., produced a significant (P<0.05) decrease in blood pressure. The statistically non-significant reduction in blood pressure was shown by 20 and 40 mg/ kg, i.v. These results suggest that Melilotus officinalis exhibited a hypotensive effect in normotensive rats. However, further evaluation of compound-related activity is required.

Dr. salman ahmed

This report on Mortality in Libya, with a particular emphasis on causes of death in the country for two years, 2016 - 2017, comes when there is a shortage of mortality studies in this country and in the developing world. The importance of death studies lies on the fact that they map out the hidden features of a community's health program. Unfortunately, there are no robust death studies in most developing countries, most of which are descriptive studies of statistical report or public survey. This study aims to read and review this report scientifically and impartially critically and to shed more light on this report. This report is the first of its kind in Libya. It discusses the causes of death in Libya for two years, 2016 - 2017. The report issued in English and Arabic languages. The report relied basically on medically documented death certificate for the death cases in hospital or home in Libya. The report indicated that there were 25 478 deaths in Libya in 2016 and 27 167 deaths in 2017, with crude death rate of 4.0 / 1000 of the population for 2016 and 4.1 / 1000 inhabitants for the year 2017. Furthermore, cardiovascular disease was the leading cause of death at all ages and sexes during the two years covered by the study. There is an urgent need for well-designed meta-analytical studies on mortality in Libya.

Mediterranean journal of pharmacy and pharmaceutical sciences

Since October 17, 2019, Lebanon has experienced unprecedented popular protests, demanding the departure of the entire political class, accused of being gangrened by corruption. Country paralyzed, institutions closed for more than two weeks, the eyes are turned to universities that have closed their doors but whose community (teachers and students) actively participate in the national jump. This study explores the use of social media by universities in Lebanon during the national revolution using social big data technology on Twitter in comparison to the national usage of twitter. Important information was collected, analyzed and visualized using the R language.

Katia raya

The samples of K1-xNaxNbO3 (X=0.4, 0.2, 0) ceramics (PSN) have been prepared by the conventional solid state reaction method and sintering process. The prepared samples have been characterized by XRD. All the prepared samples show orthorhombic structure at room temperature. Dielectric and Electrical properties of PSN system have been investigated in the temperature range 450C-2450C, and at 1MHz frequency. It is observed that dielectric constant, loss tangent and electrical conductivity increases with increasing temperature. Near the transition temperature dielectric constant, loss tangent and electrical conductivity of these samples show anomalous behaviour with temperature.

Manish uniyal

Abstract This paper evaluates the Ethiopian VAT tax type based on ten good tax principles that are: Equity and Fairness, Certainty, Convenience of payment, Economy in collection, Simplicity, Neutrality, Economic Growth & Efficiency, Transparency & Visibility, Minimum tax Gap, Appropriate Government revenue. The findings of this evaluation revealed VAT which six principles are under positive effect in Ethiopia meets of six Conon of the good tax system. Those are: Certainty for taxpayers, Convenience at the time of payment, neutrality, economic growth and efficiency, transparency and visibility, appropriate government revenue. Finally, the author suggests recommendation that could be used by the government in general and tax authorities in particularly in the preparation of future tax proposal reform and issuance of any directive, proclamation, rule, and procedure which is going to implemented need to encapsulate this Canon as Guiding route to improve service delivery and alleviating problem emanated from shortcoming from the administration.

Dereje lemma lalisho

The prevalence of vitamin D deficiency has recently been recognized in different parts of the world, even affecting healthy populations. The deficiency of vitamin D can lead to rickets in children and osteomalacia in adults. Few studies have been done to evaluate the status of vitamin D in the medical community around the world. No studies have been done in Libya to evaluate the status of vitamin D in medical students. The aim of this study was to evaluate the prevalence of low level of vitamin D in among healthy Libyan medical students of first year in University of Tripoli, Tripoli. Prospective study was conducted on 100 medical students of first year in Faculty of Medicine with a mean age of 19.5 years, 38 males and 62 females. Blood samples were taken and investigated for different biochemical parameters including serum calcium, serum vitamin D and serum parathyroid hormone levels. Questionnaire containing different data was completed for each student including personal data (age, address, nationality, and other data related to vitamin D deficiency. The prevalence of vitamin D deficiency in all the participated students was 74% (58.7% in males and 83.8% in females), while 21% had vitamin D insufficiency (28% in males and 16.12% in females). Only 5% of the students that had normal vitamin D was males. The mean 25-hydroxy vitamin D level was 19.49 ± 8.56 ng/ml in males and 12.08 ± 6.70 ng/ml in female students. Statistical analysis revealed that there is a highly significant difference among the student in vitamin D deficiency. In conclusion, low concentration of vitamin D is highly prevalent among the medical students included. An urgent action has to be taken in order to prevent adverse consequences of low vitamin D in young population.

Mediterranean journal of pharmacy and pharmaceutical sciences

Project management plays significant roles to the success of the project. The aim of the study is to review and analyze latest literature on the effects of triple constraints on the project outcome. The study is based on the secondary method whereas literatures are collected form the google scholar ranging from 2010 to 2023. After reviewing the literature, the study concludes a number of findings. The quality of the project is highly depended on the time and budget. However, inadequate management, stakeholders involvement are also play crucial roles towards project success. The study concludes a number policy recommendations.

Nazim ullah

Vigna trilobata (L.) VERDC. belongs to the family Papilionaceae, which is found throughout the tropical and warm temperate regions of the world. In folk medicine, it is used for arthritis, fever, cough, dysentery, and urinogenital disorders. Different secondary metabolites, such as alkaloids, glycosides, terpenoids, and flavonoids, have been reported in Vigna trilobata. It has antioxidant, antidiabetic, and anti-inflammatory activities.

Dr. salman ahmed

In this article, we establish the exact wave solutions of the Boussinesq equation and the (2 + 1)-dimensional extended shallow water wave equation by applying the new generalized (G'/G)-expansion method. When the condition of the fluid is such that the horizontal length scale is much greater than the vertical length scale, the shallow water equations are mostly suitable. In Ocean engineering, Boussinesq-type equations are commonly used in computer simulations for the model of water waves in shallow seas and harbors. We explained the new generalized (G'/G)-expansion method to seek further general traveling wave solutions of the above mentioned equations. The traveling wave solutions attained by this method are exposed in terms of hyperbolic, trigonometric and rational functions. The shape of the obtained solutions are bell shaped soliton, kink soliton, singular kink soliton, singular soliton, singular periodic solution and compaction. This method is very influential mathematical tool for extracting exact solutions of NLEEs which frequently arise in mathematical physics, engineering sciences and many scientific real world application fields.

Md khorshed alam