Alzheimer Disease is a chronic neurological brain disease. Early diagnosis of Alzheimer illness may the prevent the occurrence of memory cellular injury. Neuropsychological tests are commonly used to diagnose Alzheimer’s disease. The above technique, has a limited specificity and sensitivity. This article suggests solutions to this issue an early diagnosis model of Alzheimer’s disease based on a hybrid meta-heuristic with a multi-feed-forward neural network. The proposed Alzheimer’s disease detection model includes four major phases: pre-processing, feature extraction, feature selection and classification (disease detection). Initially, the collected raw data is pre-processed using the SPMN12 package of MATLAB. Then, from the pre-processed data, the statistical features (mean, median and standard deviation) and DWT are extracted. Then, from the extracted features, the optimal features are selected using the new Hybrid Sine cosine firefly (HSCAFA). This HSCAFA is a conceptual improvement of standard since cosine optimization and firefly optimization algorithm, respectively. Finally, the disease detection is accomplished via the new regression- based multi-faith neighbors’ network (MFNN). The final detected outcome is acquired from regression-based MFNN. The proposed methodology is performed on the PYTHON platform and the performances are evaluated by the matrices such as precision, recall, and accuracy.

Dr. rajasekhar butta

The wet coating of anhydrous borax powders with stearic acid (SA) to reverse their inherent hydrophilic surface properties was investigated. The coating procedure was based on the results from a previous study that revealed that the stearic acid solution (2 wt. % SA) mixed for 60 minute at 750 rpm on the magnetic stirrer was sufficient for the surface modification of anhydrous borax. For the experiments, stearic acid powders were first dissolved in water at 80 °C. The mixture obtained by adding anhydrous borax powders to this solution was vigorously mixed on a magnetic stirrer to initiation and completion the surface modification. Each of these solutions was then filtered using a filter paper to separate the undissolved particles, and the residue on paper was dried at 50 °C for 48 h until constant weighing was obtained. Wettability has been accepted as a key parameter for success in wet coating treatment. This parameter gained via the experimental characterization technique was used for an evaluation of the powder properties. The degree of wettability of anhydrous borax powders was measured and compared both after their surfaces were coated with stearic acid and after they were treated with water for a certain period of time in an aqueous environment. The stearic acid coating made the powder hydrophobic and this property was highly preserved after washing.

Journal of characterization

This report on Mortality in Libya, with a particular emphasis on causes of death in the country for two years, 2016 - 2017, comes when there is a shortage of mortality studies in this country and in the developing world. The importance of death studies lies on the fact that they map out the hidden features of a community's health program. Unfortunately, there are no robust death studies in most developing countries, most of which are descriptive studies of statistical report or public survey. This study aims to read and review this report scientifically and impartially critically and to shed more light on this report. This report is the first of its kind in Libya. It discusses the causes of death in Libya for two years, 2016 - 2017. The report issued in English and Arabic languages. The report relied basically on medically documented death certificate for the death cases in hospital or home in Libya. The report indicated that there were 25 478 deaths in Libya in 2016 and 27 167 deaths in 2017, with crude death rate of 4.0 / 1000 of the population for 2016 and 4.1 / 1000 inhabitants for the year 2017. Furthermore, cardiovascular disease was the leading cause of death at all ages and sexes during the two years covered by the study. There is an urgent need for well-designed meta-analytical studies on mortality in Libya.

Mediterranean journal of pharmacy and pharmaceutical sciences

ABSTRACT Objective: The objective of the present study was to develop an HPLC analytical method and to perform in vivo study of Emblica officinalis and Aegle marmelos extracts for antioxidant and antidiabetic activity. Methods: The phytochemical analyses, total phenolic content (TPC), TLC, DPPH assay were performed for freeze-dried Emblica officinalis fruits aqueous extract (EOFAE) and Aegle marmelos leaves ethyl acetate extract (AMLEAE). The active constituents present in both extracts were estimated by using HPLC system having Hibar® Results: Tannins, saponins, carbohydrate, glycosides are found in EOFAE; coumarins and flavonoids are found in AMLEAE and quinones, phenols are present in both extracts. The values of TPC present in standard gallic acid, EOFAE and AMLEAE were found to be 485.7, 315.6, 300.7 mgGAE/g, respectively. R C18 column [250 x4.6 mm, 5 µm] and UV detector (264 nm). A gradient mobile phase (acetonitrile and water with 0.1% trifluoroacetic acid) was used at a flow rate of 0.8 ml/min. In vivo antioxidant, antidiabetic activity of both extracts was conducted on male albino Wistar rats for 21 d in streptozotocin-induced diabetic rats (42 rats; n=6). The antidiabetic activity was measured by blood glucose level and biochemical parameters i.e. total cholesterol, triglycerides and total protein. Oxidative stress was measured by antioxidant biomarkers i.e. SOD, GSH, lipid peroxidation by thiobarbituric acid reactive substances method on the liver of the experimental rat. f Conclusion: The present study showed that the EOFAE and AMLEAE treated group III with (EOAM) low dose of 500 mg/kg body weight has potent antioxidant and antidiabetic activity. values obtained by TLC of EOFAE and AMLEAE were found to be 0.41 and 0.50, respectively. The values of % inhibition shown by EOFAE and AMLEAE in DPPH assay were found to be 97.8%±2 and 95.2%±2, respectively. The values of retention time of EOFAE and AMLEAE by HPLC analysis were found to be 4.59 and 5.28 min, respectively. Histopathological examination of the liver was revealed that low dose EOAM (containing of EOFAE 250+AMLEAE 250 mg/kg body weight) administered once a daily for 21 d showed significant activity (P˂0.001) with biochemical parameters and antioxidant biomarkers. Keywords: Emblica officinalis, Aegle marmelos, Antioxidant, Antidiabetic activity, streptozotocin, HPLC

Snehal

The purpose of this research was to examine the mediating effect of empowerment on the linkage between Total Quality Management (TQM) and service recovery performance in the hotel industry. Although much has been written about TQM, empowerment and service recovery performance, but the role of empowerment as a mediator in the relationship between TQM and service recovery performance has remained a relatively unexplored research area. A 93-item questionnaire is designed to measure TQM, empowerment and service recovery amongst employees in five-star hotels in Jordan, and 254 usable questionnaires were used in this study. Principal components analysis determined the factor structure and regression analysis determined the relationships between the study’s variables. The results revealed that the TQM implementations have positive effects on empowerment and service recovery performance. Moreover, the study found the full mediating effect of empowerment in the relationship between TQM and service recovery performance. Implications, limitations and future research are discussed at the end. This study proposes model of influence of TQM in service recovery performance, whereby empowerment fully mediates this relationship.

Mukhles m. al-ababneh

Ambon Bay consists of the inner Ambon Bay (IAB) and the outer Ambon Bay (OAB) and they are separated by the shallow sill (12 m) Galala-Rumah Tiga. The topography of the bay makes it unique and causes the exchange of water mass between those two parts of the bay does not follow the daily tidal cycle. The aim of this study was to analyze the vertical and horizontal temperature and chlorophyll-a distribution in order to know the water circulation in Ambon Bay. This study was carried out during the monsoon, in November 2018. The CTD was used to measure in situ temperature and chlorophyll-a concentration. The data were analyzed by using Surfer and ODV programs. The results show that the temperature of the surface water (0-5 m) of Ambon Bay was 29.2℃. In depth 15-40 m, temperature was different between the IAB (27.7-28.2℃) and OAB (29,2-28.7℃). Chlorophyll-a concentration was found higher in the IAB than in OAB in all depths. In the depth >12 m, chlorophyll-a in the IAB was 1 mg/m3 compared to its concentration in OAB only 0.3 mg/m3. As a conclusion, the sill in Ambon bay causes unique circulation of water mass between IAB and OAB based on the analysis of temperature and chlorophyll-a concentration distribution.

Irma kesaulya

A simple one pot synthesis has been developed for the synthesis 1,4-dihydropyridine using an efficient and reusable silica supported MgO solid catalyst by condensation of dimedone, ethyl acetoacetate, aldehyde and ammonium acetate in methanol as a solvent at room temperature. The reactions could be carried out under mild reaction conditions with very good yield of polyhydroquinoline, up to 92%. This catalyst could be recycled very easily, which makes this methodology environmentally benign.

Shilpa sangle

The transportation problem is widely applied in the real world. This problem aims to minimize the total shipment cost from a number of sources to a number of destinations. This paper presents a new method named Dhouib-Matrix-TP1, which generates an initial basic feasible solution based on the standard deviation metric with a very reduced number of simple iterations. A comparative study is carried out in order to verify the performance of the proposed Dhouib-Matrix-TP1 heuristic.

Souhail dhouib

For thousands of years, lipid based Ayurvedic formulations have been made in India, and the craft has survived down the millennia up to the present time. Some of these deliciously potent phytonutrient preparations are very popular and have sustained the test of time pertaining to their efficacy. Recent researches on the role of phytonutrients in promoting cardio-pulmonary, brain and immune health substantially buttress the philosophy underlying the use of lipids in preparing these emulsions, since a large number of these bioactives are lipophilic. Being lipoidic, they are absorbed through the lacteals in the small intestine, and are then transported through the thoracic duct directly to the heart, bypassing the liver. The formulations utilizing ghee (clarified butter) or sesame oil as the carrier lipid, either while frying the myrobalams or as Anupana (adjuvant), have special significance in modulating bodily immunity, since the immune system is housed in lymphatics which are lipid rich. Amla and lipid based Ayurvedic rasayans (rejuvenating formulations) are a popular and highly palatable group of phytonutraceutical preparations. This group of polyherbal adaptogenic formulations is classified separately from other formulations in Ayurvedic therapeutics. Several of these healthpromoting rasayans are suitable to be consumed by all age-groups in the recommended season and dose. Current research on endothelial and immune cell receptor mediated uptake of lipoidic molecules, together with the knowledge of lipid absorption pathways, lends credence to the usefulness of rasayans in targeting the cardio-pulmonary and immune systems. An attempt has been made in this paper to elucidate the mechanisms underpinning the complex interplay between lipid delivered hydrophobic phyto-molecules, systemic lymphatics and the Immune system.

Sharadendu bali

NA

Priyanka

Sexuality is a subject to be discussed without shying-away. This essay, discusses about how sexuality of a certain minority people in India and across borders, are being perceived by people in various countries and the consequences faced by the people whose sexuality seems deviant i.e. the sexual minorities from the majority . This essay provides illustrations in the form of research done by various sources that provides such evidences that paint a different picture of the sexual minorities viz. Lesbian, Gay, Bisexual, Transgender, Intersex and Queer (LGBTIQ) people in India and across the world aiming at eliminating the prejudice against them.

Hari hara sudhan r

Moringa oleifera, a very important healthful plant, is one amongst the foremost wide cultivated species of the family Moringaceae. It's extremely valued from past as a result of its large healthful properties. Moringa oleifera, native to India, grows within the tropical and climatic zone regions of the globe. It's commonly called drumstick tree or horseradish tree. Moringa will face up to each severe drought and gentle frost conditions and, therefore wide, cultivated across the globe. With its high alimentary values, each part of the tree is appropriate for either nutritional or commercial purposes. The leaves are rich in minerals, vitamins and alternative essential phytochemicals. Extracts from the leaves are useful in treatment of anemia, enhance breast milk in wet mothers. It's used as a potential antioxidant, anti-cancer, anti-inflammatory, anti-diabetic and antimicrobial agent. Thus, this study was aim to investigate the phytoconstituents from ethanolic and aqueous extracts of the Moringa oleifera cultivated in Libya and to assess its anti-bacterial and anti-diabetics activity. The phytochemical investigations of these extracts of Moringa oleifera revealed the presence of alkaloids, carbohydrates, flavonoids, saponins, steroids, tannins and phenolic compounds. The antibacterial activity of cold and hot extraction of methanolic and water extracts of Moringa oleifera by using the well diffusion method were assessed. Results revealed that there was a profound antibacterial activity of the studied Moringa oleifera against representatives of Gram-positive bacteria. After in vitro evaluation of anti-hyperglycemic properties of the ethanolic extract of Moringa oleifera by testing its capacity to inhibit α-amylase activity, the methanolic extract exhibited inhibitory effect on the α-amylase enzyme.

Mediterranean journal of pharmacy and pharmaceutical sciences

This Research Paper elucidates the challenges faced by teachers while teaching learners with learning disability. This has been conducted as a research study by the Research Scholar which explores multifaceted aspects of ‘challenges based on the responses given by the participants in the interview. It is a study designed to identify multifaceted dimensions of challenges faced by teachers while teaching learning disabled children. The research study analyzes the impact of challenges on teachers and how they are overcoming these challenges. This descriptive study was carried out as qualitative research under an Indian scenario based on Primary data available on the subject. The research enquiry focused on several research questions: What is the teacher’s understanding of learning disability? What challenges do remedial teachers face while teaching children with learning disability and how do they overcome them? What are the teaching approaches and methodology used to teach children with learning disability? The study will try to highlight the challenges faced by teachers to address them in front of the school administration. The challenges faced by teachers while teaching learning disabled children, i.e., ‘Teaching material and Curriculum structure’, ‘Behavioural issues’, ‘Lack of time’, ‘Parental expectations and Parental issues’, ‘Motivation’, ‘Self-esteem’ and ‘Emotional issues. The methods used to overcome these challenges were pointed out and analyses. Each teacher was using their own methods to tackle these challenges but some methods were used generally and an individual tailored method were developed and used according to respective learners.

Hashir ahammed a v

This study aims to determine the functional literacy acquisition of Alternative Learning System learners and make a sound basis for strategic planning and pedagogical intervention that will help promote and develop the said program. The descriptive-evaluative method of research was used in the study. The descriptive method was used to identify the respondents' profile based on (a) age, (b) gender, (c) civil status, and (d) employment status. The evaluative method was used to determine the respondents' functional literacy acquisition in (a) communication skills, (b) scientific and critical thinking skills, (c) mathematical and problem solving skills, (d) life and career skills, (e) understanding the self and society, and (f) digital citizenship (formerly digital literacy). Frequency Count and Percentage Technique was used to describe the functional literacy acquisition of the respondents. Meanwhile, a modified survey questionnaire based on the functional literacy, education and mass media survey ("National Profile of Adult Literacy and Numeracy Skills," 2004, p. 91) was used as the primary tool to gather the data. The respondents in this study were the students enrolled in ALS-Sipocot (North and South District), the school year 2019-2020. Due to COVID restrictions, other ALS learners from other municipalities were not covered as part of the study. Findings revealed that ALS learners do not yet manifest the complete acquisition of functional literacy needed to face the globalized world's challenges because their attainment of the required functional literacy skills is generally low. Moreover, the study disclosed that sex, age, civil status, and employment status affect the acquisition of functional literacy skills among ALS learners in Sipocot, Camarines Sur. Based on the results, the researcher developed an extension activity to help the ALS learners improve their functional literacy, particularly in the digital citizenship area, where they got the lowest score.

Darrel ocampo

Effect of germination and fermentation on the nutrient contents, functional and antioxidant activities of pigeon pea (Cajanus cajan) flour were investigated. The pigeon pea seeds were sorted, cleaned and processed into germinated, fermented and raw flours. The flour samples obtained were analyzed for proximate composition, mineral contents, antinutrient contents, functional properties and antioxidant/free radical scavenging properties using standard methods. The results of the proximate composition showed that the moisture content within the range of 9.62±0.02-9.96±0.01, crude protein content 16.63±0.01-24.17±0.01, crude fibre content 1.41±0.01-2.59±0.01, lipid 4.33±0.01-5.61±0.01, ash content 1.62±0.01-2.17±0.01, carbohydrate 56.80±0.02 - 62.47±0.01 and energy values 366.91 - 374.40kcal/100g. The result of elemental mineral analysis showed magnesium as the major mineral element in the sample (91.32±0.02 to 123.75±0.04mg/g), calcium (96.02 ± 0.02 - 110.14 ± 0.003mg/g), phosphorus (39.11 ± 0.02 - 46.12 ± 0.03mg/g), sodium (8.63 ± 0.02 - 12.61 ± 0.001mg/g), Iron (3.08 ± 0.02 - 4.11 ± 0.001mg/g) and zinc (2.04 ± 0.01 - 3.17mg/g) respectively. The result of the functional properties showed optimal gelatinization temperature ranged from 73.610C - 89.410C, emulsion capacity, 11.88 - 43.42%, foam stability,28.22 to 65.81%, foaming capacity,15.83 to 21.11%, bulk density,0.53 - 0.71g/ml, water absorption capacity, 1.11 and 1.51ml/g while oil absorption capacity,0.84 - 1.14ml/g. The sensory properties of the moi-moi from the processed flours showed that the colour test, (6.33 -7.53), flavour (7.63 to 7.75), taste (5.13 to 5.53), mouth-feel (7.25 to 7.36), overall acceptability (6.93±0.04 - 8.83±0.04). The results of the phenolic content ranged from 20.13mg\GAE, 53.43mg\GAE and 42.64mg\GAE for raw processed, malted and fermented samples respectively. The results of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) antioxidant activity of ethanolic extracts showed IC50values of 0.810, 1.177 and 1.014mg\ml for the raw, malted and fermented seed extracts respectively. The moisture, crude protein and fibre contents was significantly increased (p>0.05) during germination and fermentation whereas lipid, carbohydrate, ash and energy values were significantly (p<0>0.05) increased the % scavenging properties of pigeon pea extract though that of germination was higher. Malting and fermentation significantly (p<0.05) decreased the sensory properties of moi-moi produced. Based on the result obtained, regular consumption of pigeon pea will be a proactive measure against heart diseases and other related disorders in the human body.

Okechukwu obed chukwuemeka

Lakes are characterized by dynamic responses to ecological and limnologic disturbances that occur within a constrained timeframe. Some endorheic lakes in the Kenyan Rift valley are presently regarded as environmental hotspots because of complex changes that are revealed through multiple proxies; changing lake levels and surface area, turbidity and sedimentation, and the proliferation of macrophytes, and loss of aquatic biodiversity. Lake Baringo is characterized by widespread catchment degradation accompanied by high levels of turbidity during erratic and decline of the native fishery based on Oreochromis niloticus baringoensis. A careful analysis implicates potential natural factors such as catchment topography and increasing anthropogenic pressure as the main causes of lake ecosystem degradation. This paper recommends several strategies for restoration of Lake Baringo based on an integrated multi-faceted approach that combines catchment rehabilitation, pollution control, and provision of alternative livelihoods such as agriculture to the riparian communities

Omweno job

Abstract: This study was conducted on two groups of broiler , the first consists of 4 replicates of 10 birds and the second of 10 birds as each bird is a replicate in individual cages. The first group were reared on floor during the entire period ,while the second was reared in cages during the period from 2-7 weeks of age. All birds received the same ration with 2859 Kcal/ kg ME and 22% CP as a starter ration, 2995 Kcal/kg ME and 19.19% CP as a finisher ration. The results showed that cage birds had a significantly (P≤0.01) higher body weight , total and daily weight gain at all ages , significantly(P≤0.01) higher total and daily feed and protein consumption , at 2- 4 , 0-4 weeks , feed and protein conversion ratio at 4- 7, 0- 7 weeks. Also cage birds showed a significantly better growth rate at 2- 4 , 0- 7 weeks and less dressing percentage, higher wing percentage while other carcass parts did not differ significantly. The cage birds showed better economic efficiency by 27% comparing to floor birds.

Rafea mohammedtaher khulel

Trace elements are minerals present in living tissues in small amounts. Some of them are known to be nutritionally essential, others may be essential, and the remainder are considered to be nonessential. Trace elements such as zinc, copper, selenium, iron, chromium and, others are essential elements for growth and body health. They form an integral part of many enzymes and bioactive centers that are responsible for biochemical reactions such as metabolism, protein and, DNA synthesis. They are said to contribute to the development of cancer based on epidemiologic evidence. The blood level of trace elements in the human body is affected by cancer and drug treatment. The low trace elements level is a sign of leukemia patients, where cancer cells consume body nutrients and essential elements for growth. The Libyan patients were divided into four age groups and were either newly or old diagnosed with leukemia, including patients with acute leukocyte leukemia, acute myeloid leukemia, chronic myelogenous leukemia, and aplastic anemia. The samples were tested for direct aspiration onto inductively coupled plasma spectrometry at specific wave lengths. The findings showed the blood level of trace elements in leukemia patients is lower than in the healthy individuals. A negative correlation between copper and zinc levels in leukemia patients was found. The copper level increases in leukemia patients as they get older.

Mediterranean journal of pharmacy and pharmaceutical sciences

Abstract Abundant solar energy is freely available almost round the year in India. As per the current scenario of global warming and climatic change, solar energy is the cleanest source in nature. Concentrated solar power (CSP)has hardly contributed to the overall installed solar power capacity in the country. CSP technologies are Parabolic Trough Collector (PTC), Linear Fresnel Reflector (LFR), Paraboloid Dish and Solar Power Tower. This paper presents a review of CSP in solar parabolic dish concentrator to understand thermal aspect like thermal efficiency, optical efficiency, useful heat gain, heat losses, solar irradiation, etc. for various applications and current development. The current scenario of global CSP is discussed to meet the future challenges and need of the society.

Pramod wadate

Internship activities are carried out in universities to introduce the working world to students in the future. This is important to be examined, especially in terms of the effectiveness of the program that has been implemented. By conducting a survey of students who have undergone the internship process, a clearer picture can be obtained of overall student satisfaction in response to the placement process during the internship. There are five factors emerge from the data analysis, namely interpersonal skills, work environment, culture, challenges, and benefit.

L