Background: Uterine leiomyoma is the most common benign smooth muscle tumor of unknown aetiology. Progesterone may contribute to leiomyoma growth through the induction of B-cell lymphoma-2 (BCL-2) protein in leiomyoma cells. This study aims to determine the patterns of Bcell lymphoma-2 (BCL-2) and progesterone receptor (PR) expression in uterine leiomyomas seen at LTH, Ogbomoso, over a five-year period using immunohistochemical techniques.Methods: This was a hospital-based retrospective study of histologically diagnosed leiomyomas in the histopathology department of a teaching hospital between January 2012 and December 2016. A total of 141 cases of uterine leiomyomas were semi-quantitatively analysed immunohistochemically for PR and BCL-2 antigens. Results: Immunohistochemical analysis showed that out of 141 cases studied, 74 (52.5%) and 118 (83.7%) were positive for BCL-2 and PR, respectively. Among the 141 cases, 23 (16.3%) were negative for both PR and BCL-2. There was a moderate positive correlation between the immunohistochemical expression of BCL-2 and PR antigens, with a p-value < 0.001 (Pearson correlation = 0.563). Conclusion: This study showed that the majority of women with leiomyomas expressed both progesterone receptor and B-cell lymphoma-2 antigens. Therefore, selective women with leiomyomas could benefit from progesterone receptor modulators instead of undergoing invasive procedures such as myomectomy or hysterectomy.

Karishma

A mental and behavioral illness is described as a clinically significant illness with changes in thought, emotion, or behavior related to a personal situation. Objectives of the study: To assess the knowledge regarding mental health & illness and level of stress. 2. To determine the effectiveness of Educational Intervention on knowledge regarding mental health & illness and level of stress 3. To find out the association between pre-test knowledge level on mental health & illness and selected demographic variables. 4. To find out the association between pre-test stress level and selected demographic variables. 5. To find out relation between knowledge score of mental health & Illness with stress level. Methodology: Quantitative research approach with pre-experimental research design was used. Sampling: 300 samples was chosen with consecutive sampling technique. Result: In pretest mean score for knowledge and stress were 8.9 and 27.9 respectively and post-test were 19.7 and 17.45 which showed that education intervention improve the knowledge and decrease stress among adolescent. Improved knowledge reduces stress level. Conclusion: Educational intervention improve knowledge level which significantly reduce level of stress.

Dr k c yadav

Ecbalium elaterium has a very violent effect on the body and has little use in modern herbalism. Little is known about the acute and chronic toxicities of ecbalium elaterium in human. This study aims to determine the acute toxicity (LD50) of fruit extract and another aerial part extract of the ecballium elaterium in experimental animals. Thus, male albino mice were divided into different groups each group consists of six mice receiving 40, 46, 52, 61, and 69 mg/kg of fruit extract of ecballium elaterium, respectively. Other groups were given 1000, 1412, 1995, 2818, and 3981 mg/kg of the areal part of ecballium elaterium extract, respectively. The LD50 in both treatments was determined by using the Spearman-Karber method. The LD50 of the fruit and aerial parts of ecballium were 55 mg/kg and 2112.5 mg/kg, respectively. The present findings showed significant weight loss after one month of treatment with 1400 mg/kg and 40 mg/Kg of fruit and aerial part extracts, respectively. The results indicated that the fruit extract is highly toxic as compared to the extract of the aerial parts.

Mediterranean journal of pharmacy and pharmaceutical sciences

Introduction: The university experience often brings various personal and academic challenges that can negatively impact students’ mental health. This research aimed to evaluate the effect of a mindfulness program on stress, anxiety, depression, sleep quality, social support, and life satisfaction among university students. Methods: A quasi-experimental study was conducted with 128 participants, divided into experimental and waiting list control groups. The experimental group participated in a mindfulness meditation program consisting of 12 weekly sessions. Pre-test and post-test measurements were performed using the Perceived Stress Scale (PSS-10), the Zung Self-Rating Anxiety Scale (SAS), the Zung Self-Rating Depression Scale (SDS), the Pittsburgh Sleep Quality Index (PSQI), the Medical Outcomes Study Social Support Survey (MOS-SS), and the Satisfaction with Life Scale (SWLS) to assess the variables. Results: The experimental group showed statistically significant differences between the study phases and the groups after the intervention for all the variables examined (p < 0.05). The effect sizes calculated using the HC3 model were stress (η2 = 0.376), anxiety (η2 = 0.538), depression (η2 = 0.091), sleep quality (η2 = 0.306), social support (η2 = 0.704), and life satisfaction (η2 = 0.510). The mindfulness program was shown to be effective in reducing levels of stress, anxiety, and depression while also improving sleep quality, social support, and life satisfaction in college students. Conclusion: These findings indicate that mindfulness meditation may be valuable for enhancing psychological well-being in educational settings.

Paul alan arkin alvarado-garcia

Arenaria serpyllifolia L. is a medicinally important plant found in subtropical and temperate regions of the Himalayas from Nepal to Kashmir. The plant is used traditionally to treat kidney and bladder-related problems. Flavonoids and xanthone-containing compounds, such as epicatechin, japonicumone, quercetin, etc, are reported in the plants. Plants have shown Inhibitory effects on Carboxyl esterase

Dr. salman ahmed

The main purpose of the paper is to determine the correlation of consumers' demographic factors on the impulse buying behavior with respect to a number of single impulsivity indicators and one collective indicator. The paper consists of theoretical and research aspects. The first part encompasses theoretical insights into the secondary research regarding impulse buying while the practical part presents the methodology and primary research results. With respect to the subject matter, research goals as well as previous findings and primary research results, corresponding hypotheses were set and mainly confirmed. Inter variable correlation and regression analysis has been performed to test the hypothesis. The results showed that demographic factors, such as the disposable income and age, are related to most impulse buying indicators and to the impulsivity collective indicator. However, educational qualification and gender produced marginal association with impulsive buying behavior. The paper also summarizes research limitations as well as the work contribution and future research guidelines.

Abu bashar

Cet article vise à mettre en évidence les expériences et points de vue de certains auteurs sur l’apprentissage implicite du langage humain. L’apprentissage implicite est une procédure fondamentale. Le comportement devient sensible aux caractéristiques structurales. Dans le premier point de vue, il y a eu trois expériences qui ont montré que les jeunes apprenants sont sensibles aux régularités lexicales qui n’ont pas été explicitement enseignées; la deuxième expérience portait sur l’utilisation de la répétition des lettres quant à la troisième, elle portait sur la préférence des consonnes uniques ou doublées. Les résultats de ces expériences ont montré que les jeunes apprenants sont sensibles à la fréquence de doubles consonnes, à l’identité des consonnes qui peuvent ou ne peuvent pas se répéter. Les difficultés innées à l’apprentissage de la langue ont fait l’objet du deuxième point de vue. Elles sont de deux ordres: la langue en tant qu’un ensemble de séquences sonores et les indices de découverte d’un mot dans un discours. Les enfants segmentent les mots à partir de huit mois. Les connaissances procédurales se mettent en place par la répétition mentale et pratique. Les propriétés structurelles et statistiques sont à la base de l’apprentissage de la langue.

Assanvo

The purpose of this study was to find out the effects of yoga practices on selected physiological parameters of Bharathidasan University inter-collegiate men Football players. The study was conducted on thirty Football players from various colleges who have participated in Bharathidasan University Tiruchirappalli, Thanjavur Divisional tournaments 2019-2020. Subjects were randomly assigned equally into two groups, Group –I underwent yogic practices group (n=15) and group II (n=15) acted as control group. Resting pulse rate, Breath holding time and Cardio respiratory endurance were selected as creation variables. The training programme was restricted to 12 weeks and the number of session was 3 days per week. Resting pulse rate was assessed by Radial pulse method, Breath holding time was assessed by Manuel method and Cardio Respiratory Endurance was assessed by Cooper’s 12 minutes run/walk test. The data was collected from the experimental and Control Groups before and after the 8 weeks of training programme were statically examined with Analysis of covariance (ANCOVA). Resting Pulse Rate, Breath Holding Time and Cardio Respiratory Endurance showed significant difference between the groups.

Dr.i. john parthiban

Along with computer technology, the demand of digital image processing is too high and it is used massively in every sector like organization, business, medical etc. Image segmentation enables us to analyze any given image in order to extract information from the image. There are numerous algorithm and techniques have been industrialized in the field of image segmentation. Segmentation has become one of the prominent tasks in machine vision. Machine vision enables the machine to vision the real world problems like human does and also act accordingly to solve the problem so it is utmost important to come up with the techniques that can be applied for the image segmentations. Invention of modern segmentation methods like instance, semantic and panoptic segmentation have advances the concept of machine vision. This paper focuses on the various methods of image segmentation along with its advantages and disadvantages.

Manoj kumar pandey

To prevent the spread of COVID-19, the government has issued a learning policy to be carried out online (online). As implemented at Baiturrohman Elementary School, online learning is applied. This research uses a qualitative approach, and the type is a case study. Data collection techniques used participatory observation, structured interviews, and documentation—data analysis using data condensation, data presentation, and concluding. The validity of the data is source triangulation and technical triangulation. The results of this study indicate: (1) Planning the Recitation Method for Arabic Language Subjects in Online Learning at Baiturrohman Elementary School, namely: The teacher determines the goals according to the lesson plans, gives assignments according to the student's abilities, determines the types of assignments such as reading, writing, and practice. Provide instructions/resources in student books and several applications. The teacher provides time for the deadline for submitting assignments from 07.30 to 18.00 in Google Classroom. (2) Implementation of the Recitation Method on Arabic Language Subjects in Online Learning at Baiturrohman Elementary School, namely: Teachers provide guidance if they have difficulties, provide motivation to study at home, and support parents for children's learning at home; students do assignments at home independently. independent. (3) Evaluation of the Recitation Method on Arabic Subjects in Online Learning at Baiturrohman Elementary School, namely: Student assignments are written in spoken/written packages, sent in the form of photos/videos via Google Classroom, Teacher assessments via Google Classroom, Result assessment PH is done via a google form.

Educare: journal of primary education

Background: Hypertension (HTN) has emerged as a significant public health challenge and a leading cause of mortality and morbidity in developing countries like Bangladesh. Objective: This study aimed to assess the prevalence of hypertension and its associated risk factors among resi dents of Dhaka, the capital of Bangladesh, during the COVID-19 pandemic. Methods: A cross-sectional study was conducted using a multistage random sampling technique to select 305 individuals from Khilkhet Thana in Dhaka North City Corporation. Data were collected through direct surveys using a modified version of the WHO STEPS questionnaire and analyzed using SPSS version 22 software. Findings: The study identified a 34.4 % prevalence of HTN among the participants, with 46.2 % of hypertensive individuals being under 40 years of age. Of the 105 hypertensive individuals, 65 % were newly diagnosed during the study, and 11 previously diagnosed individuals were not on any medication. A significant association (P < 0.001) was observed between the prevalence of HTN and inadequate intake of fruits (OR = 3.129, 95 % CI = 1.912–5.122, χ2 = 21.328), insufficient vegetables consumption (OR = 2.199, 95 % CI = 1.356–3.565, χ2 = 10.373), high intake of fatty foods (OR = 2.387, 95 % CI = 1.465–3.890, χ2 = 12.454), and excessive salt consumption (OR = 2.771, 95 % CI = 1.677–4.579, χ2 = 16.310). Additionally, the prevalence of HTN was notably higher among overweight (46.70 %) and at-risk (22.90 %) individuals, based on Body Mass Index (BMI) and waist-to-hip ratio (WHR), respectively. The study also found significant correlations (P < 0.001) between HTN and factors such as smoking (OR = 2.824, 95 % CI = 1.601–4.980, χ2 = 13.432), kidney disease (OR = 7.534, 95 % CI = 2.694–21.070, χ2 = 19.282), general stress (OR = 3.692, 95 % CI = 2.179–6.255, χ2 = 24.896), COVID-19 related stress (OR = 3.511, 95 % CI = 2.116–5.826, χ2 = 24.712) and sleeping pattern (OR = 5.798, 95 % CI = 3.404–9.875, χ2 = 45.724). Conclusions: The high prevalence of HTN, particularly among younger individuals during the COVID-19 pandemic, highlights the urgent need for nationwide surveys, surveillance, and clinical research to accurately depict the true burden of HTN in Bangladesh.

Arafat hassan razon

Melilotus officinalis (L.) Pallas. is used traditionally to treat hypertension and chronic venous insufficiency. The high prevalence of hypertension and the side effects of antihypertensive drugs potentiate us to evaluate Melilotus officinalis. The hypotensive effect of Melilotus officinalis butanol fraction (MOBF) was investigated in anaesthetised normotensive rats. The doses of 60, 80 and 100 mg/kg, i.v., produced a significant (P <0.05) decrease in blood pressure. The statistically non substantial reduction in blood pressure was shown by 20 and 40 mg/kg, i.v. These results suggest that Melilotus officinalis exhibited a hypotensive effect in normotensive rats. However, further evaluation of compound-related activity is required.

Dr. salman ahmed

Social Network sites are one of the most prominent websites used in almost every facet of life. A social network reflects relationships among social entities, including acquaintances, co-workers, or co-authors. With the extreme success of Social networks, the misuse has also been escalated and unlocked the way for various illegal behavior and security threats. Social Network anomaly detection has become a critical topic to be explored by researchers. The nature of the input data is a significant aspect of an anomaly detection technique. In the field of anomaly detection in the social network, input networks can be classified as static or dynamic, Attributed or unattributed. The number of nodes and the connections between the nodes in static networks would not change with time. Attribute networks are pervasive in various domains and constitute a vital element of modern technological architecture, where node attributes support the topological structure in data exploration. While social networks build up over time, evaluating them as if they had been static is very beneficial. Numerous studies have been done for Anomaly detection, but to the best of our knowledge, research in static attributed anomaly detection has been very limited. This review tries to portray earlier research on detecting anomalies for social static attributed networks and thoroughly discusses state-of-the-art embedding approaches

Mohd haroon

Plants are an ancient source of medicine due to the presence of bioactive molecules of various compounds in their different parts. Convolvulus dorycnium plant belongs to the family of wind plants (convolvulaceae). The greatest variety of Convolvulus plants are broadly distributed over the world and was found in Western and Central Asia, Mediterranean, Macaronesia, East Africa, and Arabia. The plant C. dorycnium was collected from Tarhuna in Sidi Said area of Libya in May 2013. Plants belonging to Convolvulus genus contain various phytochemicals profiles. The focus of this study is on the phytochemical analysis of convolvulus dorycnium including phytochemical screening, extraction, isolation, and characterization. The phytochemical screening reveals the presence of flavonoids, tannins, saponins, steroids, carbohydrate, and coumarin in ethyl acetate and methanolic extract. Column chromatography and column chromatography and TLC were used to fractionate the ethyl acetate extract and H-NMR was used to elucidate the isolated compounds. Some compounds were isolated from the aerial parts of the plant; scopoletin, which is a phenolic coumarin (1) (7-hydroxy-6-methoxy coumarin), caffeic acid (2) (3,4-dihydroxycinnamic acid), and ferulic acid (3) (4-hydroxy-3-methoxy cinnamic acid) which are phenolic acids. The chemical constituents present in the extract have been reported to possess many biological activities

Mediterranean journal of pharmacy and pharmaceutical sciences

Urolithiasis has been a common problem for centuries and has a high recurrence. This review aims to provide comprehensive information about traditionally used antiurolithiatic plants and their scientifically proven pharmacological activities like analgesic, anti-inflammatory, antioxidant, astringent, demulcent, diuretic, litholytic, lithotriptic, antiurolithiatic, antispasmodic, ACE inhibition and Phospholipase A2 inhibition as a plausible mechanism of action. A total of 503 species, 365 genera and 119 families were cited for treating kidney stones. The most cited families are Asteraceae (41), Fabaceae (34), Lamiaceae (26), Apiaceae (21), Rosaceae (19) and Poaceae (16). The most commonly used plant parts are root and rhizome (25%), mode of preparation decoction (62%), and oral administration route in all cases. This review will provide the opportunities for the future research and development of new natural antiurolithiatic compounds.

Dr. salman ahmed

Cet article montre l’analyse des erreurs dans l’enseignement/apprentissage du Français Langue Étrangère au Ghana. Il a pour objectif principal d’analyser les erreurs commises en production écrite par les étudiants de Français Langue Étrangère (FLE) à l’Université du Ghana. Le corpus a été constitué du lexique de 100 apprenants. Les instruments de collecte des données ont été les questionnaires et les rédactions/compositions. Ces derniers ont été rédigés par les étudiants des niveaux 300 et 400. Etant donné la nature de l’étude, l’approche quantitative et l’approche qualitative ont été utilisées comme mode d’investigation. L’approche qualitative porte sur le modèle de l’analyse des erreurs proposé par Corder (1967) et l’approche quantitative met en évidence des données observables et quantifiables. Les principales erreurs rencontrées dans les productions écrites des étudiants ont été celles de la morphosyntaxe. Ces erreurs commises ont été analysés. Les recommandations de notre étude ont pour but d’améliorer la production écrite en Français Langue Étrangère.

Assanvo

Geotextiles have been successfully used for reinforcement of soils to improve the bearing capacity. In this study geotextile as a tensional material have been used for reinforcement of granular soils. Laboratory California Bearing Ratio (CBR) tests were performed to investigate the load-penetration behavior of reinforced soils with geotextile. Samples of granular soil are selected and tested without reinforcement. Then CBR tests were performed by placing geotextile in one or two layers at various depths in soil sample. The effect of the number of geotextile on the increase in bearing capacity of reinforced granular soil is discussed.

Mayura

Around the world, several oral health measures have been implemented. The most popular method is to use a toothpaste. However, chewing sticks are still used in many cultures around the world in a conventional manner. Chewing sticks have a mechanical cleansing action similar to a toothbrush in addition to their antimicrobial effect. The purpose of this study is to evaluate the effect of Miswak on the growth of Candida species and to compare it to that of toothpaste. A cross-sectional study was carried out on 120 selected randomly volunteers from January to April, 2022. Two groups of participants were used for two weeks. The participants were separated into a group used Miswak and a group use ordinary toothpaste. Samples were collected before and after two weeks in these two groups. Samples were immediately processed for microbiological phenotypic conventional methods and in vitro susceptibility testing of the microbial isolates to antimicrobial. The findings show that a significant effect of Miswak against an oral cavity candida species. Total candida count was 27.5 ± 18.48, P = 0.001 (Mean ± SD) from Miswak group and 247.0 ± 90.14, P = 0.979 (Mean ± SD) in toothpaste group. The most frequent Candida isolates organisms were C. albicans: 22 (36.67%) in the Miswak group and 24 (40.0%) in the toothpaste group, the second isolate was C. dubliniensis: 04 (6.69%) in the Miswak group and 12 (20.0%) in toothpaste group followed by C. glabrata: 02 (3.33%) in Miswak group. In conclusion, Miswak has a considerable antifungal impact immediately and after two weeks of use.

Mediterranean journal of pharmacy and pharmaceutical sciences

Patent foramen ovale (PFO) is an embryonic interatrialdefect potentially associated withischemic cerebralstrokes. One option is the occlusion of the atrial shunt byendovascular means. This procedure is recommendedfor patients with a history of cryptogenic strokes.Patent foramen ovales (PFOs) are common in the general population (prevalence 20-30%) and do not constitute a pathology in their own terms. Nevertheless, a association has been established between the occurrence of certain cryptogenic ischemic strokes and the presence of a PFO. The risk appears higher when septal patency is associated with atrial septal aneurysm (ASA). The aim of this presentation is to study the association between the PFO and the occurrence of ischemic stroke, and the benefits of its closure.

Kalkoul hamza

While today, he was ready to serve 1.4 million meals for schoolchildren, Mr.CC Das, Program Director, Akshaya Patra Foundation from Bangalore also faced the challenges 15-years before its establishment like any other start-up. Similar was the case of Mr.Trilok Gautam, Executive Supervisor, who was working in a remote village called Baran in Rajasthan. On his visit during the mid-day meal preparation, he was inspecting the quality of meal, where women were busy in preparing food. They were preparing bread by rolling the dough, while few were chopping vegetables with utmost hygienic care. Cleaner, safer, quality meal was to be prepared and served for 1,500 poor students. These children earlier used to go hungry from the school. On November 28th 2001, Supreme Court of India gave a verdict and directed the State Government and Union Territories to provide mid-day meal to every child in Government and Government-assisted primary schools. The Right to Food Law emerged as a fundamental right, enforced due to constitutional amendment under Article 32 of the constitution. Hence, every State Government geared up to make the mid-day meal scheme successful in their respective States. The Karnataka government also participated and named this programme as ‘Akshara Dashoha’. Government of Karnataka took the pioneering step to involve NGOs like Akshaya Patra as an important partner of the government to run this innovative mid-day meal scheme under the Public Private Partnership (PPP) Model. Presently, Indian mid-day meal scheme considered as one of the largest mid-day meal programme in the world has a target to reach out nearly 120 million children in the country.

Nitin mali