Wilsons disease is a rare inherited disorder which is characterized by impaired copper excretion which leads to excessive deposition of copper in many tissues and organs like brain, liver, and eye. This is also characterized by Kaiser-Fleischer ring, low serum ceruloplasmin levels and elevated urinary copper excretion [1]. A 26year male patient came to the neurology department with chief complaints of involuntary tremors of both hands and difficulty in walking in the last one month associated with swaying to one side in the last 20 days. On examination the patient is having Kaiser-Fleisher ring positive and upon further investigation Magnetic resonance imaging brain was performed which revealed the features in favor of Wilson’s disease. And for this condition the patient is treated with chelating agents and benzodiazepines.
The government has implemented the Healthy Living Community Movement (GERMAS) program by promoting the pharmaceutical sector related to drug storage at home. However, many problems still exist in storing household medicines in the community. This activity was carried out through a community empowerment approach using the community capacity-building method for a community organization, Aisyiyah, which consists of Muslim women in the Grendeng village, Purwokerto. This activity was carried out in stages, namely pre-test methods, lectures, group teaching, self-empowerment through peer teaching and training, and measuring the success of activities using post-tests. Based on the activities, partners' knowledge about storing medicines at home has increased in a good category.
Penilaian autentik ini bertujuan untuk mendeskripsikan pengetahuan guru serta menggambarkantugas-tugas riil bagi siswa untuk menghasilkan pengetahuan, sikap dan keterampilan. Teknik pengumpulan data yang digunakan adalah observasi dan wawancara. Focus penelitian ini (1) bagaimana penilaian kompetensi sikap pada pembelajaran tematik di MI Darussalam 01 Bagon Puger Jember? (2) bagaimana penilaian kompetensi pengetahuan pada pembelajaran tematik di MI Darussalam 01Bagon Puger Jember?, (3) bagaimana penilaian kompetensi keterampilan pada pembelajaran tematik di MI Darussalam 01 Bagon Puger Jember? Hasil dari penelitian ini menunjukkan: (a) penilaian kompetensi sikap meliputi sikap jujur dan disiplin, dimana mudah didalam teori, namun sulit untuk menerapkannya. Tergantung dari guru favorit masing-masing, proses pembelajaran tergantung pada materi pelajarannya, dan juga berkaitan dengan nilai atau norma. (b) Penilaian kompetensi pengetahuan, meliputi: tes tulis, tes lisan, dan penugasan, baik penugasan terstruktur dan tidak terstruktur. (c) Penilaian kompetensi keterampilan meliputi: penilaian kinerja, penilaian proyek, dan penilaian portofolio.
Dans notre système éducatif, l’accès à la formation pédagogique pour l’enseignement primaire est accessible aux personnes dotées du certificat de l’école primaire. Or, le système éducatif les plus performants organisent un dis- positif de pré-sélection afin de former les meilleurs pour assurer un enseigne- ment de qualité. Le recours à la théorie des intelligences multiples, est salutaire pour le recrutement des futurs enseignants dans notre système éducatif. A partir de cette théorie, la formation initiale des enseignants et leurs recrutements sont spécifiquement bordés de trois axes à savoir : interpersonnel, linguistique et lo- gique/mathématique, pourquoi mettre de côté les autres formes d’intelligences ? Or l’enseignant du primaire doit bénéficier aujourd’hui d’une formation totale.
For thousands of years, lipid based Ayurvedic formulations have been made in India, and the craft has survived down the millennia up to the present time. Some of these deliciously potent phytonutrient preparations are very popular and have sustained the test of time pertaining to their efficacy. Recent researches on the role of phytonutrients in promoting cardio-pulmonary, brain and immune health substantially buttress the philosophy underlying the use of lipids in preparing these emulsions, since a large number of these bioactives are lipophilic. Being lipoidic, they are absorbed through the lacteals in the small intestine, and are then transported through the thoracic duct directly to the heart, bypassing the liver. The formulations utilizing ghee (clarified butter) or sesame oil as the carrier lipid, either while frying the myrobalams or as Anupana (adjuvant), have special significance in modulating bodily immunity, since the immune system is housed in lymphatics which are lipid rich. Amla and lipid based Ayurvedic rasayans (rejuvenating formulations) are a popular and highly palatable group of phytonutraceutical preparations. This group of polyherbal adaptogenic formulations is classified separately from other formulations in Ayurvedic therapeutics. Several of these healthpromoting rasayans are suitable to be consumed by all age-groups in the recommended season and dose. Current research on endothelial and immune cell receptor mediated uptake of lipoidic molecules, together with the knowledge of lipid absorption pathways, lends credence to the usefulness of rasayans in targeting the cardio-pulmonary and immune systems. An attempt has been made in this paper to elucidate the mechanisms underpinning the complex interplay between lipid delivered hydrophobic phyto-molecules, systemic lymphatics and the Immune system.
Background: Pre-eclampsia remains a significant contributor to maternal and perinatal morbidity and mortality. Research into changes associated with the disease offers some hope into identifying predictive and prognostic factors. In recent times, serum leptin has attracted interest as a possible marker for the disease. The aim of this study was to determine and compare the serum leptin levels in normotensive and pre-eclamptic pregnant women attending antenatal clinic at the Delta State University Teaching Hospital, Oghara, Delta State, Nigeria. Methods: This was a prospective case-control study design at the Delta State University Teaching Hospital, Oghara, Nigeria in which sixty three pregnant women who received antenatal care and developed pre-eclampsia were recruited into the study. For each selected pre-eclamptic, a matched normotensive was selected as control. Serum leptin level was measured by radioimmunoassay (RIA) ELISA. Results: There was a statistically significant difference in mean serum leptin levels between the normotensive and pre-eclamptic pregnant patients 15.11±4.81 ng/dl vs 38.98±8.66 ng/dl; p<0.001. Furthermore, there was a statistically significant difference in mean leptin levels between mild and severe pre-eclampsia; 16.49±8.22 ng/dl vs 39.03±8.58 ng/dl;p<0.001.Conclusion: This study revealed an association between serum leptin level and pre-eclampsia. Serum leptin may be a potential marker for pre-eclampsia and deserves further investigation.
Background Type 2 diabetes and obesity are serious public health concerns globally and a growing burden in Africa. Both conditions have serious repercussions on health when they co-occur, yet the extent of their co-occurrence in Africa remains unknown. Therefore, this review aimed to identify the prevalence and associated factors of overweight and obesity among persons with type 2 diabetes in Africa. Method A systematic search was conducted on PubMed, MEDLINE, Embase, African Index Medicus (AIM), and African Journals Online (AJOL) for observational studies that reported the prevalence of overweight and/or obesity among type 2 diabetes patients in Africa. The prevalence data from individual studies were aggregated through a random-effects meta-analysis. The I2 statistic was used to evaluate between-studies heterogeneity, while subgroup analysis and mixed-effects meta-regression were performed to identify sources of heterogeneity. We assessed publication bias using funnel plots and Egger’s test. This review adhered to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Results Of 1753 records retrieved, 80 articles were eligible for this review, with 74 cross-sectional studies included in the meta-analysis. The pooled prevalence of overweight and obesity was 35.6% and 25.6% respectively, while the overall prevalence of both overweight and obesity was 61.4%. Also, the pooled prevalence of both overweight and obesity across the five geographical areas in Africa ranged from 56.9% in East Africa to 88.5% in Southern Africa. Nineteen factors were significantly associated with overweight and obesity among patients with type 2 diabetes. Conclusion The high prevalence of overweight and obesity among patients with type 2 diabetes is a significant public health concern that transcends geographical boundaries within Africa. The findings from this review highlight the need for innovative weight management interventions that are tailored to the cultural context of the African setting
Mobile pervasive environment interact with several devices at varying service ranges. The technical heterogeneity of pervasive environment is expected to increase the system flexibility and adaptability on modeling with context training phase. While working with context based training phase, time entity measure is considered as the significant issue. The evaluation of the services through numerous devices during training phase does not acquire an effective service monitoring on mobile pervasive environment. Mobile pervasive environment based information extraction fails to modify the patterns as activities change over time. To improve the flexibility of context training phase in mobile pervasive environment, an Active Context Source Discover Training Phase (ACSDTP) with Classifier Decision Tree Support (CDTS) mechanism is proposed in this paper. Our research work is to develop an effective modification (i.e., updation) of the pattern on training phase with real world context as per changes over time. Initially, the ACSDTP set up the available sensors in pervasive environment to work with the ever changing set of context users. The available sensors are maintained using the Active Discover process. Second, the CDTS mechanism is designed using weighted prediction for easy identification of context result on the training phase. Decision tree is operated separately using the learning techniques, where the identification is performed in a significant manner with minimal time factor. The learning process is performed to identify the inferred situations. Finally, the integration process is carried out to work with the complex association between the situations and sensor data in the mobile pervasive environment to achieve flexibility and adaptability factor. Experiment is conducted on factors such as time entity measure rate, precision ratio, and user context result determination level.
Financial accounting can be viewed as the process through which businesses record, summarize, and report their business transactions over a specified time (Yu, Lin, and Tang, 2018). Financial accounting aims to keep track of all business transactions that the business has engaged in over a specified time. Financial accounting also provides a snapshot of the financial health of the business entity. Financial accounting is crucial due to various factors. First, financial accounting ensures that proper financial statements are preferred in line with accepted accounting standards (Mita et al., 2018). Secondly, financial accounting ensures that the managers make crucial financial decisions in line with the financial statements. Financial accounting is also carried out to ensure that a business complies with the set taxation laws. Financial accounting is also crucial when valuing the business for significant events like merging and sale of the business (Homburg, Theel, and Hohenberg, 2020). Financial accounting can also provide evidence in case of legal suit and also provides crucial information to external and internal users of financial information.
Abstract should be times new roman with 9 fount single spacing.The main focused of Watermarking is developing and i Image Recognition is the idea of simulating the visual functions of human brain which uses human eyes as the source of input to recognize and make decisions on the objects it sees. This became possible with the advent of cameras and advanced processing technologies. The idea is to copy the features exactly present in the pattern, that the brain uses to recognize images [6]. The image in the real world are captured and pre-processed in the desired format and stored in large chunks of memories. This is to provide the recognition program to compare the new image taken with the ones that has been pre-processed and stored. The comparison is done at the pixel level of the image which is expressed in a matrix form. The image is compared with the data set stored at pixel level and the decisions are made recognizing the image. This picture recognition method becomes a smarter solution with the availability of more number of data sets. With large number of trail and errors the system will get familiar and intelligent providing best solution for computer and robot vision technologies.
Background: The rising global DM epidemic is driving the problem of TB control. This research determined glycemic control in TB only infected and DM-TB comorbidity and the consequence of the double burden on treatment outcome. Methods: fifty M. TB infected subjects and fifty control subjects were enrolled into the study, all the participants gave consents. FPG and HbA1c were determined by Colorimetry. Data were analyzed using SPSS version 20.0 statistical package, differences between groups and variation among groups were determined by Student’s t-test and ANOVA respectively while the association between variables by Pearson’s correlation. Differences were considered statistically significant at p<0.05. Results: The mean FPG and HbA1c levels of TB subjects were significantly (P<0.05) higher than those of the control. The mean BMI of the TB infected subjects was significantly lower (p=0.001) than that of the controls. The mean age, FPG and HbA1c of TB subjects at the beginning phase of treatment were significantly lower (p<0.05) than those of subjects at the continuation phase of treatment. The mean age, FPG and HbA1c of subjects with DM-M.TB coexistence were significantly (p<0.05) higher than those of the M.TB only infected subjects. BMI of the DM-M.TB comorbidity subjects was lower than that of the M.TB only infected subjects (p=0.109). A significant positive correlation was obtained between HbA1C and FPG in M.tb infected subjects. (r=0.910, p=0.001). A negative correlation obtained between HbA1C and BMI in M.tb infected subjects. (r=0.267, p=0.061). Conclusion: Infection with mycobacterium tuberculosis poses a risk to DM and vice versa, which may adversely affect treatment outcome and control of both diseases. Firm efforts to control DM may likely have a significant valuable effect on TB treatment outcome.
Every year, tax laws are updated to create a more straightforward tax system for every Indian taxpayer. It was determined to provide new voluntary taxation to individual assesses in the union budget under section 115BAC of income tax act 1961. This essay discusses the new optional tax system, a comparison to the previous tax system, and the applicability of optional tax in the current context. Understanding tax payers' attitudes towards optional tax and educating them about the new regime, the drawbacks of optional tax, and its implications for the upcoming fiscal year are among the objectives of this research. Data is generally gathered through questionnaires for this purpose, and various research papers and journals are read to provide better analysis. According to survey results, individuals will continue to use the old tax system because there are no deductions available under the new tax law. However, the majority of respondents concurred that the new plan is superior to the previous one since it is completely dependent on the degree of income and investment of the individual. Overall, it can be said that, if you set aside a few of the new tax scheme's flaws, it is the correct step towards becoming a significant tax reform in recent memory. Keywords: Section 115 BAC Optional tax regime, Old tax structure, Relevance.
This study examined work-life integration and female lecturers’ tasks performance in government-owned higher educational institutions in Imo state. The correlational research design was adopted for the study. Two research questions were answered while two hypotheses were tested. The population of the study comprised 1292 female lecturers in government-owned higher educational institutions in Imo State. The sample size of the study was determined using Taro Yamane formula. Proportionate stratified random sampling technique was used to draw 406 respondents from the strata. Two sets of instruments titled; Female Lecturers’ Work-Life Integration Questionnaire (FLWLIQ) and Female Lecturers’ Task Performance Questionnaire (FLTPQ) were used for data collection. Face and content validities were ensured by experts including the researcher’s supervisor. The reliability coefficient of the FLWLIQ and FLTPQ was calculated to be 0.97 and 0.95 with the help of Cronbach Alpha. Multiple and simple regressions were used to answer the research questions. ANOVA associated with multiple regression and t-test associated with simple regression were used to test the null hypotheses at 0.05 alpha level. It was found that self-management skills and effective communication system predict female lecturers’ tasks performance by 54% in government-owned higher educational institutions in Imo state. Based on the findings, it was concluded that work-life integration is positively and moderately significant to female lecturers’ tasks performance in higher educational institutions in Imo state. It was therefore recommended among others that; management of tertiary institutions in Imo state should consider the establishment of constructive outlets for female lecturers to vent any form of inconveniences that is inimical to their job functioning so as to reduce tension. Also, management in each of the institutions should communicate staff duties in an effective manner by setting up active communication channels in each faculty.
It is the goal of every company to gain the most from investment in advertising. Contrary to conventional wisdom that sustained spending in advertising is needed to maintain high levels of sales, the concept of marketing persistence suggests that short term advertising campaigns can have long-lasting impacts on sales. This study offers impact of TV advertising on choice of consumer durable goods in Coimbatore District through the use of a marketing. Significant marketing persistence was found in sales of consumer durables. Based on the findings, implications for long-term marketing resource deployment are suggested.
The labeling of medications includes the provision of information and instructions as well as a unique identity for the medical product. It is one of the most important sources of information for patients. Good labeling practice is critical to ensuring patients' safe and effective use of products. Misreading the label, insufficient data on the label, inappropriate labeling font, writing style, and placement on the dosage form can all have disastrous consequences. The objective of this study was to assess medication labeling practices among community pharmacists in Libya. A simulated client method (SCM) was used, and the study was carried out in the City of Zawia, where 146 local pharmacies were visited over three months for the investigation (January to March 2023). These visits were made at random, without the pharmacist's knowledge. The findings revealed that all dispensed drugs were not labeled, and none of the practicing pharmacists in any pharmacies visited displayed any drug label, printed or handwritten. The majority of pharmacists did not address or explain significant information to the patient in an effective manner, which led to inappropriate and harmful consumption of medications. The absence of dispensed drug labels reduces the patient's knowledge of the necessary information about the medicine, resulting in a treatment deficit or unsuccessful therapy. Thus, more effort should be made by health authorities to instruct pharmacists to use and work according to international labeling standards or to establish local labeling specifications.
Mediterranean journal of pharmacy and pharmaceutical sciences
Several pieces of research have proved that the relational effects and outcomes of service quality have a positive and significant impact on consumer satisfaction, consumer retention, consumer loyalty and consumer advocacy. The present research analysed the impact of seven relational outcome constructs on the consumer satisfaction and found that Consumer education, Physical evidence, Emotional intelligence, Social competence and Product policy, have significant and direct impact on overall consumer satisfaction The other relational outcome constructs, personalized relationship between individual customer and service employee, consumer retention and consumer loyalty have important direct effect on overall consumer satisfaction, and these three outcomes also have a direct effect on consumer advocacy. Hence, it was concluded that service quality, consumer satisfaction and consumer loyalty are positively correlated and have a significant and positive impact on consumer advocacy. The research was conducted on 300 consumers of the insurance industry.
The purpose of this study is to describe the planning, implementation and evaluation of the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember. This study uses a qualitative approach and the technique of determining data sources using purposive sampling. Collecting data through observation, interviews and documentaries. Data analysis, descriptive qualitative with data reduction steps, data presentation, conclusion drawing/verification. To check the validity of the data using triangulation of sources and techniques. The results of the research show: (1) Planning the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember, namely: determining the goal of memorizing 2 letters Al-Insyiqaq and Al-Muthoffifin, instilling a love of the Qur'an since early, Content of material, determine method, Determination of media, Determination of evaluation. (2) The implementation of the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember, namely: students memorizing letters Al-Insyiqaq and Al-Muthoffifin, reading letters according to makhraj and tajwid, Submission of material by teachers, using tilawati method by listening, imitating, reading together and repeatedly, using Juz 'Amma, Al-Qur'an and murottal media. (3) Evaluation of the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember, namely: evaluation of objectives, evaluation of material based on the target of memorizing letters Al-Insyiqaq and Al-Muthoffifin and not experiencing difficulties, evaluation of methods, formative evaluation at the end of each lesson and letter increase.
The main focus of this study is the coverage of New Straits Times (NST) of the first Palestinian General Elections for two presidential candidates namely, Yasser Arafat and Samiha Khalil. This study aimed to explore if any of Entman’s 1993 framing functions was used in the coverage of this issue and to explore whether the tone of NST coverage was negative, positive, balanced or neutral. To achieve the aims of this study, qualitative content analysis of elections stories from NST has been adopted. The number of news stories was eight, and the time frame started from 19th January to 13th February 1996, where three of these stories were published on the same day of 22nd January, two days after holding the elections on 20th January. Defining problems and diagnosing causes were the most prominent of Entman’s four framing functions presented in all the articles. The moral judgment function was included in four news stories, and suggesting remedies was included in two news stories out of eight. The findings revealed that Yasser Arafat received 50% balanced coverage, followed by 37.5% positive coverage, and only 12.5% negative coverage, while Samiha Khalil received 67% balanced coverage, compared to 33% positive coverage.
Abstract Background: Hansen’s disease is a chronic infectious disease with a wide range of clinical manifestations. The clinical diagnosis must be confirmed by histopathological and bacteriological studies in order to adequately manage the condition and prevent drug resistance. Aim: To perform a clinico-histopathological correlation of skin lesions in all patients with a clinical suspicion of Hansen’s disease. Materials and methods: A retrospective, hospital based, cross-sectional study was conducted in the Department of Pathology, Father Muller Medical College, Mangalore. Skin biopsies of all suspected cases of Hansen’s disease received over a period of three and a half years were included in the study. Haematoxylin and eosin, Fite-Faraco stained sections of all cases were reviewed. The cases were classified according to Ridley–Jopling classification into TT, BT, BB, I, BL, and LL. Clinical details of the patient, including type and site of lesion were obtained from the patient’s medical records. Clinico-histopathological correlation was done for all the cases. In addition, wherever available, the corresponding slit-skin smears were also included. Results: A total of 76 cases were clinically diagnosed as Hansen’s disease. Clinico- histopathological correlation was seen in 33/76 cases (43.42%). The most common histological subtype of Hansen’s was Borderline Tuberculoid (BT) - 24/76 cases (31.58%). Maximum agreement was seen in Mid-borderline leprosy (92.11%). Fite Faraco stain was positive in 21 out of 76 cases. Slit skin smears were available for 55 cases and positive in 20 cases. Conclusion: Due to clinical and morphological overlap, it is imperative to correlate the clinical, histopathological and bacteriological index results in order to accurately subtype the categories in Hansen’s disease.
This article investigates the integration of Artificial Intelligence (AI) with Electronic Health Records (EHR), exploring the transformative impact of this synergy on healthcare informatics. Through an in-depth analysis of recent advancements, practical implementations, and ethical considerations, the paper illuminates how AI is enhancing the efficiency, accuracy, and insights derived from EHR, ultimately contributing to improved patient care and clinical decision-making.