Cryopreservation is a process that preserves intact living cells, tissues or any other biological constructs by cooling and storing the samples to very low temperatures in order to maintain their viability and to save them for future use. At very low temperatures, enzymatic and chemical activities that may cause harm to the biological material are effectively stopped. Cryopreservation methods look to reach very low temperatures without causing further harm caused by the creation of ice crystals during freezing. Cryopreservation human samples for storage including variety of diseases such as cancer, genetic and degenerative disorders and bio-banking. This review aims to describe and highlight dimethyl sulfoxide in cryopreservation. Dimethyl sulfoxide is a non-toxic solvent and is one of the most commonly used pharmaceutical agent with a varied range of pharmacological actions including membrane penetration, anti-inflammatory effects and local analgesia as well as weak bacteriostatic. The main use of dimethyl sulfoxide is a vehicle for some drugs to enhancing the action of the drug and helping penetration of other drugs into the skin. However, dimethyl sulfoxide has been the cryopreservative agent of choice in situation to its exceptional performance in mitigating freezing-related damages. It is frequently used in cell banking applications as a cryoprotectant. When added to media, it prevents intracellular and extracellular crystals from forming in cells during the freezing process. There has been a concern over the toxicity of dimethyl sulfoxide and its potential side effects in different highly concentration after administration to patients. Therefore, there has been growing demand for robust dimethyl sulfoxide for cryopreservation method that can improve safety and maintain potency and efficacy
Mediterranean journal of pharmacy and pharmaceutical sciences
There are more and more multinational enterprises growing in Indonesia that makes foreign employees are increasing every year. Thus, it is important for local workers to understand the leadership style of expatriates from the companies’ leaders and managers. The purpose of this research is to see the effect of transformational leadership style on job satisfaction conducted at PT Musim Mas, Medan. This research uses quantitative method with simple random sampling of 36 employees working in the company. The test results show that transformational leadership style has a positive significant effect on job satisfaction at PT Musim Mas, Medan as much as 69.5%.
On January 2021, cases affected by coronavirus epidemic are constantly increasing, Libyan Ministry of Health provides the vaccine to the people those who are most at risk. The purpose of this study was to assess and verify the adverse effects of the first dose of the AstraZeneca COVID-19 vaccine. The study conducted at the Aljmail city, west region of Libya. The study was cross-sectional study during the period of August 31st and November 5th, 2021. The method involved 133 adult Libyan participants of both gender ageing more than 18 years old. The preliminary data were 54.0% who developed post-vaccination symptoms. The participant's aged 60 years and more with chronic diseases were more likely to have adverse effects after receiving the first dose of vaccine. In conclusion, AstraZeneca vaccine was good and effective but this study indicates a need for a large and long period study to confirm the safety of the vaccine use in the adult people.
Mediterranean journal of pharmacy and pharmaceutical sciences
Urolithiasis has been a common problem for centuries and has a high recurrence. This review covers the forty-nine (49) antiurolithiatic plants of the family Lamiaceae used in 11 countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.
This is a non-inclusive collection of my published articles.
The current study was conducted to determine the insoluble, soluble, and total dietary fiber content of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., legume flours, using AOAC enzymatic-gravimetric analysis. The results showed that M. uniflorum, P. lunatus, and P. vulgaris legume flours contained 155.91, 120.01, and 90.80 mg/g insoluble dietary fiber, respectively. At the same time, soluble dietary fiber was not found in any tested sample.
Abstract: This study was conducted on two groups of broiler , the first consists of 4 replicates of 10 birds and the second of 10 birds as each bird is a replicate in individual cages. The first group were reared on floor during the entire period ,while the second was reared in cages during the period from 2-7 weeks of age. All birds received the same ration with 2859 Kcal/ kg ME and 22% CP as a starter ration, 2995 Kcal/kg ME and 19.19% CP as a finisher ration. The results showed that cage birds had a significantly (P≤0.01) higher body weight , total and daily weight gain at all ages , significantly(P≤0.01) higher total and daily feed and protein consumption , at 2- 4 , 0-4 weeks , feed and protein conversion ratio at 4- 7, 0- 7 weeks. Also cage birds showed a significantly better growth rate at 2- 4 , 0- 7 weeks and less dressing percentage, higher wing percentage while other carcass parts did not differ significantly. The cage birds showed better economic efficiency by 27% comparing to floor birds.
In the context of emerging sustainability challenges, demarketing has continued to draw the attention of academicians and practitioners globally over the past few years. It is interesting to note that demarketing is as old as marketing itself, yet its application and scope have grown from the past two decades only. Kotler and Levy, (1971) has defined demarketing as “that aspect of marketing which deals with discouraging customers in general or a certain class of customers in particular on a temporary or permanent basis”. This systematic literature review attempts to enrich the discussion on demarketing research through a systematic and comprehensive review of 64 articles published between 2000 and 2022. Using TCCM framework, we present relevant theories, research contexts, study characteristics, and methodologies used in demarketing research. Our review (1) Presents a systematic and comprehensive overview of the research in demarketing over the last two decades (2) Examines studies in demarketing within the framework of ‘triple bottom line’ approach for sustainability (3) Suggests a suitable definition of demarketing considering its exorbitant application within the sustainability context (4) Identify gaps and sets agenda for future research. Our systematic literature review found that research in demarketing has been growing considerably over the past two decades, twice as much in the last decade compared to the previous decade with spill-over to new sectors. The literature review, through the lens of ‘triple bottom line’ approach, is able to establish that demarketing can be employed to effectively address the sustainability challenges encountered by policymakers and practitioners.
Introduction: Mental health disparities are deeply entrenched within the fabric of societal inequalities, shaped by structural factors that perpetuate intergenerational cycles of disadvantage. Addressing these disparities is crucial for promoting social justice and improving public health outcomes. Aim: This paper aims to synthesize high-quality evidence to elucidate the causal relationships between social determinants and mental health outcomes. It prioritizes pervasive social determinants that influence major mental disorders across the life course and outlines preventive strategies to mitigate these effects. Methodology: A comprehensive literature review was conducted, focusing on publications from the Global North from 2014 to 2024, to explore the influence of social determinants on mental health. Keywords such as "social determinants," "mental health outcomes," "preventive strategies," and "vulnerable populations" guided the search across databases like PubMed and Google Scholar. Results: The review highlights significant associations between mental health and social determinants such as socioeconomic status, racial and ethnic marginalization, and exposure to adverse environments. It underscores the heightened vulnerability of marginalized groups, including refugees, LGBTQ+ individuals, and those living in poverty. The paper introduces a preventive framework to guide primary prevention efforts and reviews both primary and secondary strategies to improve mental health equity. Conclusion: Strategic interventions aimed at the root social causes of mental health disparities can substantially enhance public mental health. This paper provides seven strategic recommendations focused on social justice, offering a roadmap for researchers, policymakers, and public health professionals to address these pressing issues.
Kegiatan keagamaan merupakan kegiatan yang amat penting di MI Negeri 3 Jember, mengingat masih banyak peserta didik yang membutuhkan bimbingan guru untuk memiliki karakter yang sesuai dengan tuntunan Islam, di zaman teknologi initidak bisa dipungkiri bahwa anak-anak zaman sekarang sudah mengenal yang namanya internet. Maka dari itu pendampingan orang tua dan guru sangat dibutuhkan dalam perkembangan anak-anaknya. Salah satu pendidikan yang diajarkan guru kepada peserta didiknya sejak dini adalah pengajaran tentang al-Qur’an.Oleh karena itu darus keliling (darling) merupakan kegiatan yang tepat dalam proses membelajarkan al-Qur’an dalam rangka menanamkan karakter religius kepada peserta didik. Fokus penelitian yang dikaji adalah: Bagaimana peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegitan ekstrakurikuler darus keliling (darling) di MI Negeri 3 Jember tahun 2019? Penelitian ini memperoleh kesimpulan: Peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegiatan ekstrakurikuler darus keliling di MI Negeri 3 Jember dalam hal ini adalah guru yang senantiasa membimbing anak-anak anggota darling untuk belajar al-Qur’an. Darling ini adalah sebuah wadah yang diberikan oleh guru untuk mengembangkan potensi peserta didik. Karakter religius pun terbentuk yakni sikap patuh dalam menjalankan agama Islam, misalnya membaca al-Qur’an. keliling di MI Negeri 3 Jember dalam hal ini menggunakan instrumen penilaian yang memiliki 3 aspekpenilaian yakni aktif, kurang aktif dan tidak aktif.
While today, he was ready to serve 1.4 million meals for schoolchildren, Mr.CC Das, Program Director, Akshaya Patra Foundation from Bangalore also faced the challenges 15-years before its establishment like any other start-up. Similar was the case of Mr.Trilok Gautam, Executive Supervisor, who was working in a remote village called Baran in Rajasthan. On his visit during the mid-day meal preparation, he was inspecting the quality of meal, where women were busy in preparing food. They were preparing bread by rolling the dough, while few were chopping vegetables with utmost hygienic care. Cleaner, safer, quality meal was to be prepared and served for 1,500 poor students. These children earlier used to go hungry from the school. On November 28th 2001, Supreme Court of India gave a verdict and directed the State Government and Union Territories to provide mid-day meal to every child in Government and Government-assisted primary schools. The Right to Food Law emerged as a fundamental right, enforced due to constitutional amendment under Article 32 of the constitution. Hence, every State Government geared up to make the mid-day meal scheme successful in their respective States. The Karnataka government also participated and named this programme as ‘Akshara Dashoha’. Government of Karnataka took the pioneering step to involve NGOs like Akshaya Patra as an important partner of the government to run this innovative mid-day meal scheme under the Public Private Partnership (PPP) Model. Presently, Indian mid-day meal scheme considered as one of the largest mid-day meal programme in the world has a target to reach out nearly 120 million children in the country.
Whitefly, Bemisia tabaci (Genn.) and yellow mosaic virus disease incidence in mungbean, Vigna radiata (L.) Wilczek is a most serious problem in northern states of India. Bioefficacy of some insecticides and biorational were tested during kharif 2010 to 2011 and 2011 to 2012 at Pulses Research Farm, Department of Genetics and Plant Breeding, CCS Haryana Agricultural University, Hisar. The results revealed that 30 days after sowing minimum whitefly population was recorded in plots, when seeds were treated with dimethoate 5 ml/kg seeds. At three days after spray application lowest whitefly population (1.6 and 6.4 adults/ cage/ plant) was noted in NSKE 5 per cent sprayed plots. At seven days after spray, NSKE 5 per cent and triazophos 0.04% was the most effective in keeping the whitefly incidence and yellow mosaic virus infection low. Triazophos and NSKE did not help in managing the whitefly population at low level up to 10 days after spray application. Spraying of triazophos 0.04% resulted in higher grain yield as well as net profit. Lower dosage of triazophos 40EC at 0.02% enhanced the whitefly population in 2011 to 2012. However, the maximum incremental cost benefit ratio (1:13.41) was obtained in dimethoate 5 ml/kg seed treated plots followed by seed treatment with dimethoate plus spraying of triazophos 0.04% (1:11.93).
Adolescents’ scholastic and social life has become increasingly reliant on the internet and mobile technology in recent years. Problematic Internet Use (PIU) is a growing problem in Indian adolescents. However, in many cases, this use has become obsessive, causing them to neglect other elements of their lives. Adolescents account for over 35% of internet users in India. The purpose of this study was to evaluate the psychosomatic problems related to internet overuse among school going adolescent students. This cross-sectional survey was conducted among 348 students in selected schools of Aspur block in Dungarpur-district, Rajasthan, India in the month of February 2016. Problematic internet use (PIU) was assessed by Young’s twenty question internet addiction test. The Depression, Anxiety, Stress Scale (DASS-42) and self structured questionnaire check list was used to measure psychosomatic problems among adolescents. Approximately 5.17% adolescents showed Problematic internet use (PIU). Adolescents with PIU were associated with age between 14-16 year, males,10th class of study, using internet since more than 3 years, being at home, mobile as a source of internet use, purpose of internet use with online gaming. Compared with normal internet users, there were significant correlation between Problematic Internet Use and Somatic Complaints r=0.3660, p<0.05, Depression r=0.3982, p<0.05. Anxiety r=0.2512, p<0.05 and Stress r=0.2886, p<0.05. Problematic internet use (PIU) is an increasing problem among teenagers and it has been linked to psychosomatic issues. Timely Effective measures are needed to prevent the spread of this problem
The strategy is a means of establishing the organisation's purpose in terms of priorities for resource allocation, action programs and long term objectives (Grant 2005). Chandler (1962) defines strategy as determining the primary long-term goals of an organisation, the adoption of courses of action, and the allocation of necessary resources. Besides, the strategy also focuses on allocating resources in relation to the organisation and its environment (Schendel & Hatten 1972). The strategy also pertains to the top management's decisions pertaining to its scope and the future direction. Such strategy covers an action plan on the organisation's future, commitments to specific products, services, and the markets.
Internet of things describes the network of physical objects such as sensors, receivers, transmitters and other technologies which are used in VCN. In Vehicular communication network two or more vehicles are communicate with each other. VCN use advanced technologies to solve transportation related problems like long traffic delays, road accidents and air pollution. IOT based technologies make vehicular network smart. In this chapter we reviewed about network resource allocation security techniques, challenges and also discuss how we can make vehicular communication network smarter. We reviewed about different models and schemes for V2V communication. These schemes were developed to ensure a fair, efficient and transparent allocation of resource in an intelligent transportation system.
Work life balance of employees has become an important issue which discusses mainly about their carrer development and the family care, it is necessary to know how the employees balance the demand for their profession and also their domestic compulsions. Professional life is hat the aim to grow and earn respect in the workplace and the society they live-in. Personal life means taking care of family, spouse, children, health and spending the available leisure time effectively. According to work foundation, the term work-life balance is about individuals having a measure of control over when, where and how they work, leading them to be able to enjoy an optimal quality of life. It is defined as establishing a successful balance between working obligations and personal commitments. Work – life balance for teaching professional has become a challenge in recent years. Teachers work load demands their time both in the institution and also extends to their home. Teaching professionals need to focus on soft skills and life skills so that they should aim at producing good citizens for the country.
La problématique de l’accès à l’eau potable soulève de nombreux enjeux de développement au regard des impacts qu’elle génère en milieu rural. C’est pourquoi plusieurs organisations internationales œuvrent aux côtés de l’Etat ivoirien afin de garantir un accès durable et sécurisé à cette ressource pour les populations. Cependant, il existe encore des zones en Côte d’Ivoire où les populations continuent de vivre au quotidien des pénuries d’eau potable. C’est le cas de la Sous-Préfecture de Gboguhé où cette problématique entrave considérablement le développement socioéconomique des villages. Partant de ce contexte, cette contribution tente d’analyser les impacts de la pénurie d’eau potable dans cette zone en s’inscrivant dans une perspective socioanthropologique. Pour ce faire, elle se base sur une approche essentiellement qualitative, mobilisant les techniques de revue de littérature, d’entretiens semi-directifs et d’observations directes pour la production de données. L’étude révèle que la pénurie d’eau potable dans la sous-préfecture de Gboguhé est un facteur de vulnérabilité chez les populations locales au regard des impacts sociaux, économiques, sanitaires et territoriaux qu’elle entraîne.
Customers shopping behaviors have altered because of technological advancement and widespread of internet access. The rise in online sales presents both opportunities and challenges for many e-commerce companies. To successfully increase the customers’ purchase intention, it is important to implement persuasion marketing strategies especially in the online environment, together with other traditional marketing techniques available. The goal of this study is to determine which technique, between Scarcity Tactics and Liking Tactics, has more impact on customers’ Purchase Intention. Zalora Indonesia, as one of the leaders in fashion, beauty, home and lifestyle e-commerce, is chosen to be the research object. Scarcity Tactics and Liking Tactics are the independent variables used in this study, with customers’ Purchase Intention as the dependent variable. Quantitative method using a causal strategy, with an online questionnaire has been delivered to 120 Zalora Indonesia buyers. According to the findings of this research, customers who buy online have the tendency to do purchases when Zalora Indonesia uses Scarcity Tactics and Liking Tactics in its marketing approach. Scarcity Tactics, however, has more influence on online Purchase Intention, whereas Liking Tactics has a promising but insignificant impact. Both Scarcity Tactics and Liking Tactics show influences in customers’ Purchase Intention as much as 60.2%.
Object: In the competitive world of the market economy, every economic unit tries organizing everyday activities. Creating a set of suitable and cost-efficient organizational structures and making competitive products and services, top managers should find the mechanisms of building alternative ways of organizational structures. Methods: This paper presents the traditional and modern management structures, their historical steps, and developed methods. In this footfall of the market economy, companies in developing countries should build their management system’s organizational structure. They should advance a management system, managerial behaviours, and new management styles of developed ones. For this purpose in this research has learned organizational structures of developed companies. The investigation discusses the emergence, formation, and modern appearance of management structures that evaluate organizational structures’ importance in enterprises and companies’ activities, using vivid examples. Findings: Then, it has shown some forms of developed organizational structures of companies with the assessment of their highest role in management. In the conclusions and recommendations, we offer our approaches to solving existing organizational problems using the historical period of development to this day.
Université Nazi Boni
Central Council For Research In Unani Medicine, Ministry Of Ayush, Government Of India, New Delhi