The butanol fraction of the leaves of Castanospermum australe Cunn. & Fraser., was tested on adult Callosobruchus analis (pulse beetle) for its insecticidal activity by impregnation method at concentrations of 3, 9, 48, 240 and 354 μg / cm2. The result showed that the extract is toxic to Callosobruchus analis and the LD50 was found to be 38 µg/cm2. The insecticidal activity of the butanol fraction of Castanospermum australe leaves against adult Callosobruchus analis was determined by impregnation method in five different concentrations and the result so obtained revealed that the extract is toxic against the test insect (pulse beetle). The mortality was lowest (14 %) at 3 µg/cm2 and highest (96 %) at 354 µg/cm2 (Table). The LD50 by log-log graph was found to be 38 µg/cm2. It may be said that the saponins of this plant could be utilized as a natural insecticide that could be an effective alternative for insect pest management.

Dr. salman ahmed

в статье анализируются основные причины и критерии иностранных инвестиций, основная роль внедрения инновационных технологий в рыночную экономику. А также роль иностранных инвестиций в модернизацию экономики Узбекистана.

Ikboljon odashev mashrabjonovich

Developing automated systems with a reasonable cost for long-term care for elders is a promising research direction. Such smart systems are based on realizing activities of daily living (ADLs) to enable aging in place while preserving the quality of life of all inhabitants in smart homes. One of the research directions is based on localizing items used by elders to monitor their activities with fine-grained details of the progress. In this paper, we shed the light on this issue by presenting an approach for localizing items in smart homes. The presented method is based on applying machine learning algorithms to Radio Frequency IDentification (RFID) tags readings. Our approach achieves the required task through two stages. The first stage detects in which room the selected object is located. Then, the second one determines the exact position of the selected object inside the detected room. Additionally, we present an efficient approach based on gradient boosted decision trees for detecting the location of the selected object in a real-world smart home. Moreover, we employ some techniques of over- and under-sampling with data clustering for improving the performance of the presented techniques. Many experiments are conducted in this work to evaluate the performance of the presented approach for localizing objects in a real smart home. The results of the experiments have shown that our approach provides remarkable performance.

Shadi abudalfa

Hydatid disease or hydatidosis is a worldwide zoonosis disease caused by the tapeworm of Echinococcus granulosus and still widely endemic in Tunisia especially in rural areas where the sheep-dog cycle is dominant. It is an important public health problem in the pediatric age group causing significant morbidity and mortality. We report a case of primary hydatid cyst of the small intestine in a child and we want to highlight the difficulty that we meet in the diagnosis despite the contribution of imaging.

Sameh

This study investigated the connection between translanguaging and reading comprehension of Filipino ESL intermediate learners. The respondents were intermediate pupils enrolled in the selected central schools in Bicol, Philippines. The respondents' ages range from 8 to 12 years old, and 124 students (27.55%) were males while 326 students (72.44%) were females. The descriptive-correlational method was used in the study. The descriptive method was used to describe the reading performance of the ESL intermediate learners and their translanguaging factors, while Pearson Product Moment Correlation was used to determine the relationship between the two variables. The primary instruments used were validated teacher-made reading comprehension test and translanguage factors survey questionnaire. Data disclosed that the general reading comprehension of the ESL intermediate learners along with vocabulary, drawing inferences, and getting the main idea, are very satisfactory. Meanwhile, the different translanguaging factors, along with personal, teacher, and social, were surveyed and identified in the study. The statistical test revealed that the reading comprehension of the respondents was significantly correlated with the identified translanguaging factors. Thus, it is recommended that teachers should promote group discussions and allow open interactions in the classroom. Teachers should allow the use of both the home language and English; employ translanguaging pedagogy in teaching reading; foster an understanding and acceptance of linguistic differences; promote multilingualism, and allow indigenous languages to be used in education to facilitate meaningful learning.

Darrel ocampo

This paper compares different optimizable machine learning classification models to predict eight types of anemia from complete blood count (CBC) data. For the research, we used a publicly available Kaggle dataset containing 1281 observations, 14 predictors, and the diagnosis as the categorical target variable with nine categories (eight types of anemia and the healthy category). First, we examined the dataset and observed the histograms of some of the predictors. We compared the values of predictors of observations with no anemia to the observations where any anemia was diagnosed. Next, we used MATLAB R2024a to train and test nine optimizable machine-learning classification models. These models were Ensemble, Tree, SVM, Efficient Linear, Neural Network, Kernel, KNN, Naïve Bayes, and the Discriminant. Bayesian optimization was used to optimize the hyperparameters of all these models. We used 90% of observations for training and 10% of observations for testing. During the training, 10-fold cross-validation was used to prevent overfitting. The results showed the best accuracy was reached with the Ensemble classification model using the bag ensemble method (validation accuracy: 99.22%, test accuracy: 100%). Finally, we inspected our best classification model in more detail. We calculated the permutation feature importance to determine the contribution of each predictor to the final model. The results showed 6–7 important predictors, while the most important feature was the amount of hemoglobin.

Ladislav végh

The seeds of Phaseolus vulgaris are known as common beans or kidney beans. The dry seeds are eaten as pulse and are enriched with protein, fiber, starch, B vitamins (B1, B6, B9), iron, potassium and selenium. Beans also contain about 1-2 % of fixed oil. Phaseolus vulgaris is linked to anticancer, antihyperlipidemic, hypoglycemic, and antioxidant actions. The fixed oil of Phaseolus vulgaris (PVFO) seeds is extracted with hexane and used in this study to assess acute oral toxicity, analgesic (by acetic acid-induced writhing, hot plate and tail flick tests in mice) and antiinflammatory (by carrageenan-induced paw edema in rats) actions. Four groups were made (n=6): Group-I: Normal Saline Control (2ml/kg), Group-II: PVFO (2ml/kg), Group-III: PVFO (4ml/kg) and Group-IV: Standard Acetylsalicylic acid (ASA 300 mg/kg). PVFO in 2ml/kg and 4ml/kg doses demonstrated analgesic and anti-inflammatory activities, but in hot plate, results were unreliable as significant activity started after 90 minutes. A 5ml/kg dose was administered orally in mice for a toxicity test, and no toxicity symptoms were observed. Therefore, PVFO is safe for oral use up to 5ml/kg and may possess analgesic and anti-inflammatory actions.

Dr. salman ahmed

This dissertation aimed to critically investigate how UK manufacturing companies can employ 3PL services to enhance business profitability. A simple, cross-sectional sequential mixed methods research methodology was implemented with the qualitative phase being used to explain the findings of the quantitative phase, which was performed first. Data for the quantitative period were collected using an online questionnaire that was designed and administered through a Google survey (N= 416). At the same time, semi-structured interviews were performed via Zoom calls with senior executives and managers of UK manufacturing firms (N= 5). Descriptive statistics, a one-sample t-test, and stepwise regression were used for quantitative data analysis using SPSS while manual analysis of interview data was performed in Microsoft Excel. The results showed that transportation and fleet management were the services that UK manufacturing companies outsourced to the most significant extent while clearing and forward and inventory management were the services that were outsourced to the lowest degree. The reasons behind this trend included the level of risk involved in outsourcing a particular service, availability of 3PL providers offering the outsourcing service, and the cost involved. In terms of feasibility, all items were scored highly, although increased operational flexibility and significant reduction of operational costs ranked highest. Finally, the stepwise regression test revealed four statistically significant models with an overall prediction power of 20.1% on business profitability. The statistically significant predictor variables were a reduction of operational costs, increased operational flexibility, reduced fixed asset costs, and the gaining of external resources from 3PL service providers.

Mohamed sorogy

Technology and Isolation in the Information Period explores the social, political, and legal implications of the group and use of personal information in computer databases. In the Information Period, our lives are documented in digital case books maintained by hundreds (perhaps thousands) of businesses and government agencies. These case books are composed of bits of our personal information, which when assembled together begin to paint a portrait of our personalities. Technology has changed our working practices and now allows us to be connected 24/7. We have the power to Skype clients around the world and email or Tweet work colleagues at weekends, but is there a danger that having connectivity so readily available hinders our efforts to gain a better work/life balance? We often read articles about the correct way to manage technology and how to achieve a happy balance of relaxing away from work and being ‘Always On’ and ‘Always available’. For instance, many people choose a job that allows them to detach from the workplace on evenings and weekends, yet technology makes it difficult for others to switch off. Now, we are huge believers in the ability to use the internet, email, Facebook, Twitter, texting and to pick up the phone and talk to people, but because of technology more people are becoming distracted and losing focus. They can’t escape from the workplace and feel that the office follows them around via their Smartphone which demands attention 24/7. It wasn’t so long ago that when we took a holiday, we would plan ahead, make sure everything was order, inform clients of our absence and brief our teams so we could disappear off to distant shores and happily sit in the sun for a relaxing fortnight, avoiding drinking the local water, eating strange local delicacies and fending of mosquitoes. But I digress … Having technology at hand means that we still have an element of control at our workplace and the ability to deal with issues if they occur. The downside to this is managing that work/life balance again. On one hand the internet is a lifeline, but it can also become a ball and chain if we don’t take the time to unplug from it. Technology allows us to be in two places at once, but when employees struggle to find the right balance between their work and personal lives there is a chance that stress levels can increase leading to a potential loss of productivity and happiness in general. In a recent survey 70% of workers said that technology brings the stress of work into their personal lives. Many Researchers have recommended drawing a line between work communications and home. This not only benefits your well being, but benefits your employer too, as you will be coming back to work refreshed and recharged.

Sunita singh

The incidence of diabetes mellitus has increased globally making it a major public health concern. Diabetes mellitus is the most common metabolic disorder that causes an imbalance in the electrolytes which regulate essential metabolic mechanisms of the body. This study aimed to estimate the electrolyte levels in Libyan patients with type II diabetes mellitus and to investigate their relations to glycemic control and body mass index. A total of 122 Libyan subjects whose ages ranged between 35 years and 60 years for both sexes were included in this study, 77 patients were type II diabetic patients (37 males and 40 females) and 45 subjects were healthy individuals (23 males and 22 females) live in Tripoli area, Libya. The levels of blood glucose, HbA1c, sodium, potassium, chloride, magnesium and calcium were estimated in this study along with the measurement of body mass index, systolic and diastolic blood pressure. All the findings were statistically analyzed by one-way ANOVA test. Significant increases in glucose, HbA1c, potassium, chloride, calcium, blood pressure and BMI among diabetic patients were observed as compared to the healthy individuals. On the other hand, significant decreases in sodium and magnesium levels among the diabetic patients were observed as compared to the control group. In addition, significant alterations in all the biochemical parameters in uncontrolled diabetic patients as compared to the controlled diabetic patients, and in unhealthy weight diabetic patients as compared to the healthy weight patients. It is concluded that diabetes mellitus results in an imbalance of electrolytes. Poor glycemic control and obesity have adverse effects on electrolyte balance among diabetic Libyan patients. Good glycemic control, maintaining a healthy weight and regular evaluation of electrolytes among diabetics can reduce the fatalities associated with electrolyte rearrangements.

Mediterranean journal of pharmacy and pharmaceutical sciences

Celiac disease (CeD) is a complex disorder characterized by gastrointestinal (GI) symptoms as well as extraintestinal manifestations, sometimes difficult to diagnose. Commonly referred to as a childhood disease, adult CeD is a well-known entity that should be included in the differential diagnosis of chronic diarrhea or malabsorption syndrome. The pathogenesis involves a genetically mediated autoimmune pathway. In individuals with genetic susceptibility, the mucosa of the small intestine is damaged in response to foods containing gluten. The clinical presentation is variable and ranges from typical GI symptoms to extra-intestinal and systemic manifestations. Clinical improvement and restoration of the intestinal mucosa occur simply by eliminating gluten from the diet. We reported a case of CeD in a young man after 6 years of iron deficiency anemia (IDA), without asserting a clear etiology during this time. In our country, the search for CeD in patients with IDA is usually forgotten and we hereby put it in the spotlight.

Karishma

Yield Analysis of Maize Hybrids Lenient to Turcicum Leaf Blight Disease in Southern Districts of Karnataka

Veerabhadraswamy al

Avian leukosis virus is recognized as an important viral pathogen in the poultry industry, resulting in salient severe economic losses due to reduced production, uneven flock growth rates, reduced growth, and immunosuppression which predispose affected birds to other infections. This study examined the seroprevalence of avian leukosis virus (ALV) in local chickens (LC) in 5 different live bird markets (LBMs) in Kaduna Metropolis. A total of 276 sera were tested for ALV p27 antigen using enzyme-linked immunosorbent assay (ELISA). An overall seroprevalence of 28.3% (78/276) was recorded in the study. At the market level, the seroprevalence of 35% (21/60), 30% (18/60), 32% (16/50), 28.6% (16/56), and 14% (7/50) were recorded for Sabon Tasha, Central market, Railway station, Kawo and Sokoto Road LBMs respectively. With regards to sex, female LC showed a significantly higher prevalence of 30.5% (46/105) compared to male chickens 26.9% (46/171) with no significant difference (P > 0.05) observed. This study established the presence of antigen to ALV in local chickens sold in LBMs. We recommend surveillance and further studies on the isolation, molecular characterization and pathogenicity of ALV in the study area.

Bitrus inuwa

Vehicle-to-vehicle (V2V) communication is an advance application and thrust area of research. In the current research, the authors highlighted the technologies which are used in V2V communication systems. Advantage of such technology is that it helps to detect live location and tolling. It plays an important role if there are huge amount of traffic. The current research work can obtain more information about Li-Fi, RFID, VANET, and LORAWAN technology. Li-Fi is known as VLC communication system that uses visible light for high data transmission and reception. RFID technology helps the emergency vehicle to reach destination quickly by avoiding any kind of traffic. LORAWAN is a large-scale network technology with a long range and VANET with low power that allows to obtain accurate traffic information on each route and this saves time. The comparison between the different technologies is reviewed in order to obtain the optimized technology as per the applications.

Vartika agarwal

Vigna aconitifolia (Jacq.) Marechal. (Papilionaceae) is a medicinally important plant used for treating different diseases, especially dermatological disorders. Alkaloids, phenols, flavonoids, and phytic acid have been reported in this plant. Vigna aconitifolia also exhibits antioxidant, antidiabetic, and hypocholesterolemic activities. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.

Dr. salman ahmed

The valuable effects of regular exercise for promotion of health and therapy of diseases were obviously evaluated. The notion that exercise can be considered as a medication has been hypothesized. The growing problems of obesity and non-communicable diseases have placed a great burden on public health experts to promote physical literacy and physical activity among the modern day population. Physical literacy and physical activity have become the cornerstones of women’s health. Women have certain special needs that includes reproductive health. Increased physical activity and maintaining normal body image and body weight will help a woman attain physical, mental and spiritual development. With the growing number of women with obesity and the implication of obesity as one of the main risk factors for non-communicable diseases like diabetes, hypertension, stroke and osteoarthritis, a knowledge and awareness about physical activity is essential. Thus, physical activity is a fundamental aspect of the improvement of motor skills and work performance, allowing a better healthy lifestyle. Physical exercise is effective to be measured as a drug, however, more care should be considered to the dosing and individual variations between genders.

Mediterranean journal of pharmacy and pharmaceutical sciences

Cyperus esculentus (tiger nut) seed is the parent of many products like flour, milk, starch, and oil. All these share similar and sometimes better properties when compared to similar products obtained from other sources. This study aimed to produce and characterize a cream made from oil extracted from tiger nuts. The proximate analysis was tested by the established methods and data obtained show that tiger nut powder has a moisture content (14.50%), an ash (1.98%), a fat (51.27%), a protein (8.47%), fiber (13.94%) and carbohydrate (9.98%). The oil from the tiger nut was extracted using the hot press method, the tiger nut oil had an 8.00% yield. The oil was used to produce a body cream which was characterized and tested for its antibacterial activity. Its antibacterial activity showed inhibition against Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, and Pseudomona aeruginosa. The characterization tests gave results of 1735.80 cP for viscosity, moisture content (1.07%), pH of 6.10, ash (5.11%), volatile matter (94.89%), electrical conductivity (390 µS/cm), spreadability at 30oC was 145.28 g.cm/s, at 35oC was 149.41 g.cm/s and 152.25 g.cm/s at 40oC. The cream was checked for stability and found to be stable at different temperatures. It was checked for allergens and it exhibited some level of allergic reactions. Physicochemical analysis of the golden-brown oil indicated the specific gravity (0.98), density (0.98 g/ml), acid value (1.82 mg/KOH/g), iodine (37.75 mg), peroxide (2.00 meq/kg), saponification (236.32 mg/KOH/g), free fatty acid (0.91%) and refractive index (1.46). The GC-MS analysis identified a total of 22 compounds. Oil, with the major constituents being palmitic acid (13.70%), oleic acid (18.50%), oleamide (31.25%), acexamic acid (4.68%), stearic acid (2.99%), squalene (2.87%) by composition. The study reveals that oil from tiger nut seed is useful when applied in the production of body creams and has possible uses in the production of antibacterial ointments.

Mediterranean journal of pharmacy and pharmaceutical sciences

Vitamin C causes a significant change in pharmacological effects of some drugs which may lead to unpredictable responses. Vitamin C-haloperidol interaction has not been confirmed in vivo. This study was aimed to investigate the influence of vitamin C on some pharmacological effects of haloperidol (extrapyramidal side effects caused by the antipsychotic haloperidol). Albino male mice (n = 24, body weight of 20 - 40 gm) were divided into four groups and each of consists of six mice. Group I (control): given 1% Tween 80 solution, group II: given vitamin C in a dose of 100 mg/kg, group III: given haloperidol (2 mg/kg), while group IV: given a combination of vitamin C and haloperidol. All the treatments were given by intraperitoneal route of administration. Three sub-acute doses of different treatments were given at 24:0, 5:0, 1:0 hour before scoring. Parameters scored were catalepsy, ptosis, rigidity and akinesia. The experiment was repeated using vitamin C in a dose of 500 mg/kg. Both doses of 100 and 500 mg/kg of vitamin C significantly antagonized the effect of haloperidol by decreasing all the tested parameters. The results indicate that vitamin C decreases extrapyramidal side effects caused by the antipsychotic haloperidol and show that it successfully decreases catalepsy, ptosis, rigidity and akinesia in mice.

Mediterranean journal of pharmacy and pharmaceutical sciences

Immunoglobulin G4-related disease (IgG4-RD) is a rare and new but increasingly recognized immune-mediated fibroinflammatory condition known to affect multiple organs. The diagnostic approach is challenging, as there is no single investigation to confirm the diagnosis, which requires the integration of clinical, biochemical, and radiographic manifestations with classic histopathologic features to establish the diagnosis. The histology of IgG4-RD is determined by a dense lymphoplasmacytic infiltrate, storiform fibrosis, and obliterative phlebitis in the presence of an increased level of IgG4 in most patients. The first line of treatment is systemic glucocorticoids, but adverse effects of the drug, suboptimal response, and disease recurrences on reduction or termination of therapy highlight the need for an alternative therapy such as rituximab, which appears to be a promising alternate agent in the treatment of IgG4-RD; however, its efficacy needs to be evaluated in large clinically controlled trials.

Karishma

Motherhood has true nobility and unique capacities. Pregnancy and childbirth are special events in women’s lives. This study aimed to assess the effectiveness of Infra-red radiation therapy on pain perception and wound healing among primi postnatal women with episiotomy in Christian mission hospital, Madurai. The study was conducted among 60 postnatal women, 30 in experimental group and 30 in control group, who were selected by using purposive sampling technique. Data collection was done as planned 6 weeks were taken for data collection procedure. The data gathered were analyzed and the interpretation was made on the study objectives. The paired‘t’ test and independent‘t’ test were used to find out the effectiveness of infrared radiation therapy. Comparison of pain perception and wound healing status values between pre-test and post-test, experimental and control group showed a significant difference at 0.05 levels. The study concluded that the infrared radiation therapy was effective in reducing episiotomy pain and wound healing. Therefore, infra-red radiation therapy should be used to augment the therapy of episiotomy. Keywords: Pain perception, Wound healing, Episiotomy, Infrared lamp

Elsi queen