The rate of oxygen consumption was measured in mercury chloride treated freshwater fish, cyprinus carpio for 96h and compared to control group. The present investigation showed that average oxygen rate was decreased in all treated animal as compared to controlled group. Behavioural changes was also recorded in both concentration. The behavioural alterations observed like surfacing, erratic movement, increased mucous secretion, decreased opercular movement and loss of balance. The present study revealed that, mortality rate increased with increases in concentration.

.vijay digambar suryawanshi

Urolithiasis is a common problem that has been afflicted for centuries and has a high recurrence. This review covers the sixty-four (64) antiurolithiatic plants of the family Fabaceae used in 18 different countries and their historical antiurolithiatc background. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. salman ahmed

Objective: To explore unusual association between Turner Syndrome (TS) and Hypopituitarism in a Tunisian cohort. Methods: We reported 6 patients with TS associated to Hypopituitarism, including three familial cases except the fourth sister who showed only a TS phenotype. Biochemical analysis, resonance magnetic imaging and cytogenetic analyses were performed. Results: The average age of our patients was 17.2 years (11-31 years). They were all referred for short stature and pubertal delay, except for the fourth sister who presented spontaneous puberty with the integrity of the pituitary axis and the presence of an X ring chromosome. Karyotype analysis showed monosomy in 3 cases and a mosaic TS in the 3 remaining cases, including one patient with abnormal X chromosome structure. Somatotropic and corticotropic deficiencies were confirmed in 2 sporadic cases while the gonadotropic and thyrotropic axes were spared. In contrast; familial cases were consistently affected by the integrity of the corticotropic axis. MRI showed pituitary hypoplasia in all familial cases and pituitary stalk interruption syndrome in only one sporadic case. No correlation was found between the chromosome formula and the anterior pituitary involvement. Conclusion: Co-segregation of congenital Hypopituitarism with pituitary hypoplasia and X chromosome aberrations could imply a molecular anomaly of transcription factors responsible for the differentiation and development of pituitary cells such as PROP1, POUF1, Hesx1, Lhx3, Lhx4. The etiopathogenic link between X chromosome abnormalities and the occurrence of Hypopituitarism remains unclear; however, the progress of molecular biology may clarify the interrelation between transcription factors and sex chromosome segregation abnormalities.

Mariam moalla

The “Green AI Revolution” distils a paradigm-shifting methodology for creating machine learning solutions for the design and enhancement of ecologically sustainable communication networks. To address sustainability concerns in communication infrastructures, this study presents a comprehensive architecture that emphasises the integration of machine learning (ML) and artificial intelligence (AI) techniques. With the fitting moniker “Green AI”, the suggested model aims to improve overall resource efficiency in communication networks while minimising energy usage and carbon footprints. The goal of Green AI is to transform conventional communication systems by utilising sophisticated algorithms, dynamic optimisation, and intelligent decision-making techniques. Higher energy efficiency, less of an impact on the environment, and better network performance are the main goals. The present study examines the fundamental elements of the Green AI architecture, encompassing intelligent routing, dynamic power management, and adaptive power distribution of resources. Furthermore, case studies and simulations highlight the real advantages of incorporating machine learning into communication networks, highlighting the technology’s potential to make a substantial contribution to a future that is more environmentally friendly and sustainable. The Green AI Revolution is a paradigm shift in the way we think about and use communication technology. It encourages innovation that is in line with environmental stewardship and technical progress.

Mrutyunjaya s yalawar

For many decades, the lean concept has been praised for improving efficiency, maximizing productivity, and minimizing waste in manufacturing operations. Lean production is expected to create an industrial ecosystem that is more cost-efficient and accountable for optimizing resources and processes. However, in the context of lean manufacturing, new challenges have emerged as a result of the recent emphasis on sustainability. This study aims to show several criticisms of lean implementation and propose a holistic approach to achieve a more sustainable operation. The green-lean model, sustainable manufacturing, agile supply, and Lean 4.0, are approaches for integrating lean practices and sustainability. This will foster a culture of continuous improvement, employee empowerment, long-term collaboration with suppliers, added value for customers, and increased innovation in the economy.

L

his study explored the English Language Teaching appraisal of teachers in the trifocal Philippine education system in the Bicol Region as a basis for policy and advancement programs. This study used the descriptive-comparative-associational method using a content-validated and reliability-tested questionnaire. The frequency and percentage technique, weighted mean, Chi-Square, and Anova Test of Variance were used in the data treatment. Findings revealed that ELT teachers were predominantly females with 73.97%, CHED, 80.21%, DepEd, and 71.43% TESDA along age groups of early and mid-30s and 46 years above. They served the agencies for less than 10 years, mostly married. Professionally, these teachers were still pursuing post-graduate education and attending training. Along with appraisals on their professional and work responsibility, ELT Trifocal teachers very evidently performed their professional and work responsibilities; on the delivery system, respondents conveyed the mastery and application of theoretical and pedagogical knowledge; on their communicative competencies, they were classified as experts. Meanwhile, there was no significant difference among ELT teachers’ appraisal in the three systems (F–value 2.21< t-value 3.35; 5% level of significance). It follows that Philippine education has maintained an undeviating quality of ELT teachers regardless of which system of education they belong. The result showed no variations in ELT competencies despite differences in modalities, urgencies, and the attainment of quality education. Findings also unveiled that the ELT teachers’ appraisal and integration of ICT to language teaching are directly associated with their age, sex and civil status, and educational attainment. The higher the educational attainment, the higher the integration of ICT in language teaching. With these results, a policy development for the Professional Advancement Program in ELT was crafted.

Darrel ocampo

Abstract Background: Hansen’s disease is a chronic infectious disease with a wide range of clinical manifestations. The clinical diagnosis must be confirmed by histopathological and bacteriological studies in order to adequately manage the condition and prevent drug resistance. Aim: To perform a clinico-histopathological correlation of skin lesions in all patients with a clinical suspicion of Hansen’s disease. Materials and methods: A retrospective, hospital based, cross-sectional study was conducted in the Department of Pathology, Father Muller Medical College, Mangalore. Skin biopsies of all suspected cases of Hansen’s disease received over a period of three and a half years were included in the study. Haematoxylin and eosin, Fite-Faraco stained sections of all cases were reviewed. The cases were classified according to Ridley–Jopling classification into TT, BT, BB, I, BL, and LL. Clinical details of the patient, including type and site of lesion were obtained from the patient’s medical records. Clinico-histopathological correlation was done for all the cases. In addition, wherever available, the corresponding slit-skin smears were also included. Results: A total of 76 cases were clinically diagnosed as Hansen’s disease. Clinico- histopathological correlation was seen in 33/76 cases (43.42%). The most common histological subtype of Hansen’s was Borderline Tuberculoid (BT) - 24/76 cases (31.58%). Maximum agreement was seen in Mid-borderline leprosy (92.11%). Fite Faraco stain was positive in 21 out of 76 cases. Slit skin smears were available for 55 cases and positive in 20 cases. Conclusion: Due to clinical and morphological overlap, it is imperative to correlate the clinical, histopathological and bacteriological index results in order to accurately subtype the categories in Hansen’s disease.

Archana

Hypnea pannosa J. Agardh (a methanol extract of the whole alga) was subjected to antifungal screening. The extract showed good activity against Trichophyton longifusus, low activity against Candida glabrata, and inactivity against Fusarium solani.

Dr. salman ahmed

Dignity therapy (DT) is an evidence-based psychotherapeutic approach originally designed to alleviate emotional and existential distress in patients with terminal illnesses. While dignity therapy has been well documented in palliative care, emerging perspectives suggest that its principles such as promoting autonomy, meaning, and self-worth can be beneficial for persons with severe mental illness (SMI) who often experience stigma, identity loss, and existential suffering. Although severe mental illness and terminal illness are distinct conditions both may involve the profound psychological and existential challenges that affect personal dignity. This paper explores the philosophical foundations and therapeutic benefits of dignity therapy, with a particular focus on its potential application in mental health settings. It highlights the significance of preserving dignity in psychiatric care and emphasizes the need for compassionate, personcentered mental health support tailored to the lived experiences of the person with severe mental illness.

Karishma

Social Network sites are one of the most prominent websites used in almost every facet of life. A social network reflects relationships among social entities, including acquaintances, co-workers, or co-authors. With the extreme success of Social networks, the misuse has also been escalated and unlocked the way for various illegal behavior and security threats. Social Network anomaly detection has become a critical topic to be explored by researchers. The nature of the input data is a significant aspect of an anomaly detection technique. In the field of anomaly detection in the social network, input networks can be classified as static or dynamic, Attributed or unattributed. The number of nodes and the connections between the nodes in static networks would not change with time. Attribute networks are pervasive in various domains and constitute a vital element of modern technological architecture, where node attributes support the topological structure in data exploration. While social networks build up over time, evaluating them as if they had been static is very beneficial. Numerous studies have been done for Anomaly detection, but to the best of our knowledge, research in static attributed anomaly detection has been very limited. This review tries to portray earlier research on detecting anomalies for social static attributed networks and thoroughly discusses state-of-the-art embedding approaches

Mohd haroon

The aim of this study is to identify the move from cultural to creative cultural tourism as new model for meeting tourists' demands for creative experiences. Hence, traditional cultural tourism must reinvent itself as creative tourism for those creative tourists seeking more interactive experiences. This new trend in creative cultural tourism has emerged from the changes in the production of cultural tourist commodities, the skilled tourist activities, and new consumption patterns. Moreover, creative cultural tourism can solve those problems experienced by traditional cultural tourists. A literature review confirmed that a move to creative cultural tourism, or intangible heritage (i.e., linguistic diversity or gastronomy), from tangible cultural attractions (i.e., museums, monuments, and so forth) increases the attractiveness of tourism destinations. In addition, this study explains the transformation from traditional cultural to creative cultural tourism.

Mukhles m. al-ababneh

The bioactive phytochemicals are the most important bioactive compounds against insect herbivores. These phytochemicals produced by many legumes and react herbivore attacks. Therefore, keeping in mind the said facts, this review discusses the potential use of bioactive compounds like Proteinase inhibitors, trypsin inhibitors, lectins, vicillins (7S storage proteins), phenolics, amino acids, sugars and a-amylase inhibitors in legume plants as most important weapons that confer resistance against herbivorous insects. These inhibitors inhibiting proteases present in the larval gut and has insecticidal potential against insect pests. This review demonstrates the potential of natural phytochemicals from legume plants and or artificially diet incorporate to inhibit the development of pathogens and insect pests. Thus, legumes can be used to produce phytochemicals as bio-pesticides and minimize or avoid the use of agrochemicals in crop protection. This ability making them interesting bioactive for next generation of sustainable pesticides for more sustainable agriculture.

Dr. babu lal jat

In the last decade, we have observed the usage of artificial intelligence algorithms and machine learning models in industry, education, healthcare, entertainment, and several other areas. In this paper, we focus on using machine learning algorithms in the loan approval process of financial institutions. First, we briefly review some prior research papers that dealt with loan approval predictions using machine learning models. Next, we analyze the loan approval prediction dataset we downloaded from Kaggle, which was used in this paper to compare several machine learning classification models. During this analysis, we observed that credit scores and loan terms are the attributes that probably most affect the result. Next, we divided the dataset into a training set (80%) and a test set (20%). We trained 27 various machine learning models in MATLAB. Three models were optimized with Bayesian optimization to find the best hyperparameters with minimum error. We used 5-fold cross-validation for the validations to prevent overfitting during the training. In the following step, we used the test set on trained models to measure the models’ accuracy on unseen data. The result showed that the best accuracy both on validation and test data, more than 98%, was reached with neural networks and ensemble classification models.

Ladislav végh

Over the recent years, cloud computing has emerged as a powerful means for providing automated healthcare facilities. Cloud helps in massive sharing of information between doctors and hospitals using Electronic Health Records. This major transformation has changed the way doctors and hospitals deliver quality and effective service to their patients. Using Cloud storage inhealthcare services has revolution- ized health industry, making it more efficient. Apart from the primary driving factors of cloud like flexibil- ity in cost of maintenance, infrastructure and development, on-demand scalability of storage centers and pay on use schemes are proven to be most effective. More and more digitalization of data causes breech of security and privacy.Because healthcare information is a highly sensitive data which cannot be com- promised,the future of healthcare relies in providing secure and trustworthy sharing of data by safe- guarding privacy and trust. This paper gives an extensive review of the existing security mechanisms for Cloud based healthcare systems.

Dr.c.priya

A 25-year-old male presented with vaguely painful and pruritic vesicles and bullae on the oral cavity, abdomen, and superior limbs with symmetrical dissemination, which appeared over the past 3 weeks. No clinical history of importance. The physical examination showed a pallid and prostrated patient, with arterial hypertension (190/110); with several symmetrical dermal vesicles and bullae located on the abdomen and superior limbs (Fig. 1) and on the oral cavity varying from 1.5mm to 4 cm. No lymphadenopathy and sigs of arthritis were identified. Laboratory tests revealed a complete blood cell count with hemoglobin levels of 10.5 g/dL (12.7–15.7 g/DL), leukocytes of 2956/mm3 (4.3–10.7 × 103), and platelet count of 120,000/mm3 (150–350 × 103). Urinalysis shown proteinuria, hematuria, and leukocyturia. The direct Coombs assay, anti-nuclear antibodies, anti-double-stranded DNA, and anti-histone were positive. Histopathological analysis reported subepidermal discontinuity associated with neutrophilic infiltrate and direct immunofluorescence was positive for IgG, staining the basement membrane. Elisa was positive for antibodies against type VII collagen. The diagnosis was bullous systemic lupus erythematosus (BSLE) and he was treated successful with rituximab due to poor response to steroid use.

Karishma

By using mathematical vectors calculations as financial modeling then further into a new form of quantitative analysis instrument for linear financial computation graphs. A new tool in financial data analysis as an indicator

Dr abdul rahim wong

Diabetes mellitus is the most common health disorder and one of the leading causes of death. It is such a sort of disorder in which the patients are at all the time on risk of complications. Numerous investigations discovered that oxidative stress plays an important role in the development of vascular complications in diabetes particularly type 2. There are several chemically induced animal models of type 1 diabetes mellitus. The most common chemicals used to generate type 1 diabetes mellitus animals are alloxan and streptozotocin. Alloxan is added to food materials, especially to the all-purpose flour (maida) to bring softness and white color to the flour. Hence, consuming foodstuffs made from this flour can lead to diabetes mellitus. Measuring the concentration of alloxan in the blood of children with type 1 diabetes. 45 volunteers (children 5-15years) in this study. 15 healthy and 30 patients with diabetes mellitus (females: 53.0%, and males: 47.0%). Venous blood was taken from the elbow vein and transferred as soon as possible into deproteinization solution without any contact with oxygen. Average blood levels of alloxan are determined by the Archibald spectrophotometric method. The mean level of alloxan between healthy and diabetic groups statistically is insignificant (Median=0.458) and diabetic group (Median=0.806). Low-carbohydrate diet low adherence diabetics (46.6%, median=1.91), low- carbohydrate diet moderate adherence diabetics (26.6%, median=0.89), low-carbohydrate diet high adherence diabetics (26.6%, median=0.1). The findings indicate that the alloxan level is higher in healthy people compared to diabetic volunteers whose follow a low-carbohydrate diet, in addition to the reducing of their pastry intake.

Mediterranean journal of pharmacy and pharmaceutical sciences

Cystic fibrosis is a challenging disease which creates many complications. The impact caused from cystic fibrosis on an adolescent is a challenging phase for their lives. Negative impacts like the society’s pressure, anxiety and depression are few common reasons that are being unspoken and ignored due to complexity of the disease. This study is aimed to identify the necessary gaps and educate the necessary policy makers and CF center health care team to have a better understanding about the context of the aftermath of cystic fibrosis and enhance better patient care. More over this systematic review also points out the main trends in this field of study. Qualitative study and quantitative are prominently used research methods to gain an understanding the about the gaps in the research. However, there is still a scarcity of quantitative and mixed research methods. Furthermore, limitations such as language, cultural influences were identified whilst going through the analysis. Overall through the information given in the following in this study more information regarding that warrants answers can be identified which will lead to proper care towards the teenagers who suffers from cystic fibrosis.

Chanitha pemasena

One of the most common situations in the management process is problematic situations or conflicts, where each complex situation or conflict has unique consequences, and neglect to find the best way out of such situations put the leader in a more difficult situation. Especially at a time while COVID-19 is putting the world community in a very difficult situation, difficult to resolve conflicts, universal conflicts, the role of leaders, managers are discussed, problem solutions are proposed through management theory.

Ikboljon odashev mashrabjonovich

Potassium Bromate (KBrO3) is an oxidative agent capable of causing hematological alterations and other toxic effects. Amaranthus Viridis (Inine) is a medicinal plant traditionally used for various therapeutic purposes. This study investigated the ameliorative effect of ethanol extract of Amaranthus viridis (Inine) on the haematological parameters in potassium bromate (KBrO3) intoxicated Albino Rats. Thirty (30) rats divided into six (6) groups consisting of five rats each, group one as the normal control, group two as the negative control (50 mg/kg of KBrO3 only), group three Vitamin C (100 mg/kg) + 50 mg/kg of KBrO3and group four to six (200 mg/kg, 400 mg/kg, and 800 mg/kg) respectively. KBrO3 exposure significantly altered some haematological indices in the rats indicating a haematotoxic effects. The results showed a dose-dependent improvement in several haematological parameters upon coadministration of Amaranthis viridis occurred. The red blood cell count (RBC), packed cell volume (PCV), haemoglobin concentration (Hb), and white blood cell count (WBC) exhibited notable recovery in comparison to the KBrO3-treated group. Platelet count (PLT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) also demonstrated positive alterations in response to the extract. The group receiving the highest dose of the leaf extract (800 mg/kg) alongside KBrO3 displayed the most significant improvement in the aforementioned parameters, indicating a potential dose-dependent protective effect against KBrO3-induced haematotoxicity. These findings suggest the potential therapeutic efficacy of Amaranthus viridis extract in mitigating KBrO3-induced hematological alterations.

Okechukwu obed chukwuemeka