Abstract In every hospital, Casualty department deals with the emergency cases. These emergency cases also includes medicolegal cases like road traffic accidents, Poisoning, assaults are dealt in the casualty and detailed MLC report is made here after giving the proper primary treatment and life saving measures. The police is informed about MLC as early as possible. Important preventive measures like drawing public attention and awareness towards traumatic casualties can help in the prevention or management of unnatural (medicolegal cases). Considering the importance of above points, a one year retrospective study from 1st March 2018 to 31st March 2019 was conducted in the Casualty department of Tertiary Care Centre.

Dr. avinash harishchandra waghmode

Background The prevalence of diabetes is escalating globally, underscoring the need for comprehensive evidence to inform health systems in effectively addressing this epidemic. The purpose of this study was to examine the patterns of countries’ capacity to manage diabetes using latent class analysis (LCA) and to determine whether the patterns are associated with diabetes-related deaths and healthcare costs. Methods Eight indicators of country-level capacity were drawn from the World Health Organization Global Health Observatory dataset: the widespread availability of hemoglobin A1C (HbA1c) testing, existence of diabetes registry, national diabetes management guidelines, national strategy for diabetes care, blood glucose testing, diabetic retinopathy screening, sulfonylureas, and metformin in the public health sector. We performed LCA of these indicators, testing 1–5 class solutions, and selecting the best model based on Bayesian Information Criteria (BIC), entropy, corrected Akaike Information Criteria (cAIC), as well as theoretical interpretability. Multivariable linear regression was used to assess the association between capacity to manage diabetes (based on the latent class a country belongs) and diabetes-related deaths and healthcare costs. Results We included 194 countries in this secondary analysis. Countries were classified into “high capacity” (88.7%) and “limited capacity” (11.3%) countries based on the two-class solution of the LCA (entropy = 0.91, cAIC = 1895.93, BIC = 1862.93). Limited capacity countries were mostly in Africa. Limited capacity countries had significantly higher percentage of their deaths attributable to diabetes (adjusted beta = 1.34; 95% CI: 0.15, 2.53; p = 0.027) compared to high capacity countries even after adjusting for income status and diabetes prevalence. Conclusions Our findings support the report by the Lancet commission on diabetes, which suggests that differences in diabetes outcomes among countries may be explained by variations in the capacity of and investments made in their health systems. Future studies should evaluate initiatives such as the WHO Global Diabetes Compact that are currently underway to improve the capacity of resource-limited countries.

Emmanuel ekpor

The current COVID-19 is now endemic on everycontinent and becomes the most challenging outbreaks over centuries, thus millions of people have been infected with the novel coronavirus (SARS-CoV-2), and have contributed to the deaths of more than two millionpeople. Researchers are working continuously to develop safe and effective vaccines that people have started receiving since December 2020. Vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are the most important countermeasure to the COVID-19 pandemic taking into considerationthat vaccines induce a robust immune response

Mediterranean journal of pharmacy and pharmaceutical sciences

Neurological sicknesses are severe, multifactorial, debilitating disorders that may cause neurodegeneration. Neuroprotection protects the structure and capacity of neurons from affronts emerging from cell injuries instigated by an assortment of specialists or neurodegenerative diseases. Various neurodegenerative diseases, including Alzheimer's, Parkinson's, and epilepsy, afflict many people worldwide, with increasing age representing the leading risk factor. Crocin is a natural carotenoid compound with therapeutic potential in managing neurological disease. In this review, we focused on the therapeutic capabilities of Crocin as a neuroprotective agent. The general neuroprotective impact and the various conceivable essential components identified with Crocin have been examined. In light of the substantial proof indicating the neuro-pharmacological viability of Crocin to different exploratory standards, it is concluded that Crocin exerts direct antioxidant, antiapoptotic and anti-inflammatory activities by multiple signalling pathways. Besides, Crocin was found to elevate dopamine levels in the brain during the experimental model of Parkinson's disease. Thus, this compound has been demonstrated to be a promising option for treating neurodegenerative diseases with few adverse effects. It should be further considered as a potential contender for neuro-therapeutics, concentrating on the mechanistic and clinical evidence for its effects.

Dr. salman ahmed

During the last two decades, the concept of Fibre Metal Laminates (FMLs) has been evolved to find solution to the requirement of improving mechanical properties and reducing structural weight of elemental components of aircraft structures. In this work FML is prepared using Al 2024 by placing alternately with glass/carbon/aramid Fibres. From experimental results of FML shows greater advantage in mechanical properties then aluminium monolithic layer and this composite fibre laminates individual. The FMLs tested in this work were made of 3 layers of 2024 T3 aluminium alloy 0.28 mm thickness and fibre mats. The 5-3/2 laminates of size 300x300 mm with 3 mm thick were prepared using Vacuum Assisted Resin Transfer Moulding (VARTM) in cold compaction and test specimen were cut by using abrasive water jet machining as per ASTM Standards. The adhesion between fibre and metal layer will play a major role in strength of FML. By keeping this in consideration FMLs were prepared without blow holes and capable of withstanding delamination while preparing specimens through water jet and during various tests employed. The fracture surfaces of destructed specimens are studied with help Scanning Electron Microscope (SEM) image. Similarly, the numerical simulation of all the tests were done using Ansys APDL 10.0 Software. It is observed that aramid FML have substantially stronger in longitudinal directions. Hence, more priority given in this paper to investigate tensile strength and fatigue life of aramid FML.

Boopathy govindarajan

Streptococcus bovis/gallolyticus was considered as lower grade pathogen involved in endocarditis. Recent accumulating evidence has suggested that Streptococcus bovis/gallolyticus plays an important role in the initiation and development of colorectal cancer. This study was aimed to address the association between Streptococcus bovis/gallolyticus and colorectal cancer among Libyan patients, to determine the dominant biotype of Streptococcus bovis/gallolyticus associated with colorectal cancer patients and to evaluate the antibiotic susceptibly patterns of isolated strains. The study involved 20 colorectal cancer patients, 20 patients with large adenomas polyp and 20 people with healthy colonic mucosa as a control group. All the candidates were subjected to colonoscopy and histopathological examinations and conformation. The suspected and normal cases were then diagnosed according to the protocol used by the medicine specialist and grouped in accord with the study aim. All biopsies were handled and treated to isolate the suspected positive colonies of Streptococcus bovis/gallolyticus. Of the 20 colorectal cancer patients, seven patients (35%) were found to be Streptococcus bovis/gallolyticus carriers, (95% CI 1.22 - 1.72, p < 0.05). Nine patients (45%) were diagnosed colorectal cancer positive at age above 60 years old, eight patients (40%) at age 40 - 60 years old and three patients (15%) at age bellow 40 years old. Also, nine out of 20 patients (45%) with large adenomas polyp were found to be Streptococcus bovis/gallolyticus carriers, (95% CI 2.16 - 2.71, p < 0.05). Of the 20 healthy people with colonic mucosa, Streptococcus bovis/gallolyticus never been isolated. Streptococcus. bovis biotype II/I and Streptococcus. equinis were both susceptible to the above mentioned antibiotic classes, although Streptococcus bovis biotype I was highly resistance to most clinically used antibiotics. However, there was strong relationship between Streptococcus bovis/gallolyticus and colorectal cancer or large polyp formation. However, it is not well understood whether the bacterium has a pathogenic role in the initiation and progression of neoplasia or just an epiphenomenon of colorectal neoplasms.

Mediterranean journal of pharmacy and pharmaceutical sciences

Celiac disease (CeD) is a complex disorder characterized by gastrointestinal (GI) symptoms as well as extraintestinal manifestations, sometimes difficult to diagnose. Commonly referred to as a childhood disease, adult CeD is a well-known entity that should be included in the differential diagnosis of chronic diarrhea or malabsorption syndrome. The pathogenesis involves a genetically mediated autoimmune pathway. In individuals with genetic susceptibility, the mucosa of the small intestine is damaged in response to foods containing gluten. The clinical presentation is variable and ranges from typical GI symptoms to extra-intestinal and systemic manifestations. Clinical improvement and restoration of the intestinal mucosa occur simply by eliminating gluten from the diet. We reported a case of CeD in a young man after 6 years of iron deficiency anemia (IDA), without asserting a clear etiology during this time. In our country, the search for CeD in patients with IDA is usually forgotten and we hereby put it in the spotlight.

Karishma

Bhaishajya kalpana is an art and science of preparing and dispencing medicine. Guggulu is a Niryasa (oily latex) achieved from small tree called Indian bedellium. Botanical name is commiphora mukul. Guggulu is an amorphous, translucent, solid adhesive, oleo-gum resin is produced by the process of gummosis from its plant. Many other Ayurvedic classics have mentioned various formulations of Guggulu for the treatment of various ailments. Bhashajya ratnawali followed various kalpana use for formuations. Guggulu kalpana is secondary formulations of bhaishajya kalpana. . Guggulu is one among the best binding agents and its used as single or compound drug in the form of pills, Formulations which contains Guggulu as main ingredient, they can be called as Guggulu kalpana. Here in Bhaishajya Ratnawali, Guggulu is used in yoga for both purposes, as a base and as well as medicament also.In bhaishajya Ratnavali Guggulu when modified into different formulations. It can also be used in many diseases along with different combinations of drugs with their anupana, Guggulu kalpana beneficial in treating many diseases. The Guggulu Kalpana is indicated in almost all the strotovikaras and also a number of research works have been proved the wide range of action of Guggulu .

Suri abhiram

In Libya, pharmacy education and practice have a similar pattern to medical education and practice. Both sectors of public and private pharmacy education and pharmacy practice still significantly unchanged for more than forty years. It is a traditional pharmacy style of education and practice with a limited change of education and practice. Now, there are more than ten public pharmacy colleges and more than five private colleges established in Libya for a population of seven millions. In addition, there are several intermediate pharmacy institutes which provide a middle degree in pharmacy practice with a very limited knowledge in pharmaceutical sciences and training. Practice of pharmacy in Libya is still a classical mode with only dispensing medicines directly in almost a nonprofessional way and an old fashion way. However, the situation is old and complicated that needs a great deal of attention from different health policymakers and authorities such as Ministry of High Education and Ministry of Health, National Pharmaceutical Union and Libyan Association for Pharmacists.

Mediterranean journal of pharmacy and pharmaceutical sciences

Anemia, iron deficiency and iron deficiency anemia are common blood disorders. The role of vitamin D was agreed to be regulating in calcium and phosphate absorption and bone metabolism and its deficiency is observed as a crucial nutritional problem. Vitamin D is created under the skin by ultraviolet light. It is usually get vitamins from the food; however, in the case of vitamin D, there simply are not enough rich food sources for people to get adequate amounts in their diet. Its effects on the prevention of diseases such as cardiovascular disease and anemia has received much attention recently. To get sufficient vitamin D, need to be exposed to sunshine or use supplements. Vitamin D3 was found in the largest population as a deficiency. With regard to hemoglobin was the subject whom has less normal range of hemoglobin (19.05%) than international normal range, and in ferritin the low population number was the subject whom has less normal range of ferritin than WHO normal range. The population who has low ferritin also has low vitamin D3 and variable hemoglobin. According international guidelines, optimizing nutrition with daily or intermittent (1 to 3 times per week) iron supplementation, should be considered a first-line intervention in high-risk or high-prevalence groups. Although it is probably less effective than daily iron supplementation, intermittent iron appears to be a useful and cost effective way of controlling anemia and iron deficiency anemia. This may indicate that a positive relation between the low concentration parameter of vitamin D3 and ferritin level but no significant correlation with hemoglobin.

Mediterranean journal of pharmacy and pharmaceutical sciences

The need for natural medicine and nutrients from natural product sources cannot be overstressed. Plant parts like leaves, stem, root, seed, nut and flowers supply enormous minerals, phytochemicals and other bioactive constituents apart from the primary metabolites. Terminalia Catappa (T. catappa) is a combretaceous plant often found in tropical and subtropical regions. The plant has many uses as an ingredient of various drugs such as anti-oxidants, anti-inflammatory, anti-cancer, and anti-diarrheal. Thus, the main objective of this study was to determine the proximate, mineral and physicochemical analysis of T. catappa seed nuts. The proximate composition was determined according to the previous standard methods and elemental analysis by Atomic Absorption Spectrophotometry and Flame Photometer. Proximate composition revealed a moisture content of 02.34%, ash 03.89%, fibre content 08.50%, crude protein 29.66%, fat 21.98% and carbohydrate 33.63%. Elemental analysis of the plant have indicated the presence of iron, zinc, calcium, magnesium, potassium, sodium, copper and chromium in the aqueous extract. Physicochemical parameters of the plant revealed a specific gravity of 0.9182, viscosity 33.62 mm2/s, refractive index 1.4642, acid value of 0.102 mg KOH/g, saponification value of 151.28 mg KOH/g, iodine value 47.19 g I2/100 g and peroxide value 8.93 meq/kg. In conclusion, the findings from this study confirmed that almond nut oil has a long shelf life which may explain its applications in pharmaceutical, non-pharmaceutical and personal care industries.

Mediterranean journal of pharmacy and pharmaceutical sciences

Fused silica capillaries treated with N, N-didodecyl-N, N-dimethylammonium bromide was used in capillary electrophoresis to separate basic proteins using ammonium acetate as BGE at pH 4.0, 70 mM. This surfactant forms a semi-stable coating that provides a strong anodic electroosmosis; however, such coating must regularly be regenerated to maintain efficiency and reproducibility. The temporal stability of the coating was greatly improved by a new procedure as described in previously study by our group. In this study, it is found such experimental conditions that the starting zone could be enriched without loss of sample. The injection of a short plug of the BGE diluted 100 times for 3 sec in 50 µm i.d. capillaries behind the sample zone at 15 kV gave the best performance, whereas, a plug of lower dilution degree (10 times) in 25 µm i.d injected for 3 sec at the same field strength gave the optimum results for this dimension. In conclusion, those conditions were found to effectively decrease the loss of sample and to give a higher separation performance in regard to peak efficiency and resolution compared to injecting the sample without a plug.

Mediterranean journal of pharmacy and pharmaceutical sciences

The market for tertiary educational institutions, most especially for private universities, is highly competitive. The competitive nature of the market requires that Private Universities (PUs) step up their performance so as to remain competitive despite the major structural and market differences between them and public universities in the provision of tertiary education. The need for private universities to remain competitive in this turbulent market, calls for some careful examination of the factors that would enable private universities to enhance their performance. In this respect, this study sought to examine the effects of management competence, firm-level institutions, and human resource management (HRM) bundles on the performance of private universities in Ghana. Underpinned by the RBV and AMO theories, the study tested four hypotheses that sought to explain the relationships between the key variables of the study. The study was implemented using a quantitative research design. Out of the sixteen private universities sampled, thirteen private universities responded. The main research instrument was a structured questionnaire. Out of 230 questionnaires administered, 127 completed questionnaires were received and used for analysis. Collected data was analyzed using descriptive and inferential statistics (regression analysis) with the aid of SPSS software version 20 and AMOS version 23. Research findings from the tests of hypotheses established that management competence positively and significantly affected performance of private universities in Ghana. Though the study found that the composite variables of firm-level institutions and HRM bundles did not moderate the relationship between management competence and PU performance, the skills bundles (which is a component of the HRM bundles) significantly moderated the management competence – PU performance relationship in such a way that at high levels of skills bundle, management competence influences PU performance more than at low levels of skills bundle. Based on the findings of the study, it is recommended that PUs in Ghana institute competence acquisition and utilization policies, maintain appropriate firm-level institutions and HRM bundles and match these to their competence development strategies.

Cyril domeyelle dery

The objective of the paper is to predict corporate bankruptcy of selected telecom service sector companies. The study ranges for a period of ten years from 2006-2007 to 2015-2016 for three selected telecom service sector. By applying Altman's Z-score model the study analyze the financial position of the companies and suggests the financial components to be concentrated to improve the financial health. Further the study suggests that the companies should regularly estimate Z-score for making strategies to improve their financial position.

Dr. jeyalakshmi p

Woman constitutes the family, which leads to the development of society and Nation. The social and economic development of women is necessary for the overall economic advancement of any society or a country. Entrepreneurship comprises venture activities that are the center of the recognition of various opportunities, creativity, and innovation in the production process and development of new business models and ventures. Entrepreneurship plays a major role in developing society of a fastdeveloping country like India. In comparison to other countries, the event of women entrepreneurship is extremely low in India, especially in rural areas. However, middle-class women aren't too eager to alter their roles because of fear of social backlash. The growth is more visible among high families in urban areas. Rural women frequently have primary responsibility for agricultural production, additionally to domestic responsibilities and childcare. In developing countries like India where the economic status of women is extremely pathetic especially in rural areas and opportunities of earning are very less. For establishing self-esteem and recognition in society, women are attracted to entrepreneurship. To sustain within the competitive market, businesses administered by women are mainly hooked into internal resources and their capabilities supported which they struggle to compete with the external environment. The present paper endeavors to study the opportunities and challenges of women entrepreneurs. The study aims to analyze the factors that encourage women entrepreneurs. This study is based on secondary data collected from previous research papers, journals given by various research scholars, blogs, and websites. This study concludes that women entrepreneurs should be provided with special training facilities to overcome challenges and for developing their skills and talents.

Mamta gaur

Establishing a realistic working profile of soil properties has been, and is still, one of the most challenging problems facing Geo-technical engineers, especially for CBR results. In the present study a neural-network approach is used to tackle this problem. Source data of a series of California Bearing Ratio Tests (CBR) performed at the Laboratory and Geo-technical Experimental Site. This will be useful for training and testing an artificial neural network. The developed neural network will be showing the prediction of CBR values of the site studied. Data are then generated for constructing the profiles of the CBR values using the trained neural network. This study might be useful for the future as this process will reduce the work on procedure and graphical calculations.

Mayura

Tracing graduates has become an imperative for higher education institutions much more during the pandemic. This tracer determined the employment and employability status of the 2019 BSE graduates and identified the competencies they adequately acquired and deemed vital for work. It used descriptive design, and data were collected from the 103 graduates through a Google form with open and closed-ended questions administered between November and December 2020. Results revealed that most of the graduates had been employed in teaching and teaching-related jobs but mostly in contractual arrangements within the first and second six months after graduation. Many had their first jobs with meager salaries from the private sector. Communication, pedagogy, information communication technology, time management, and flexibility were the top competencies they adequately acquired and were beneficial in work. The study concluded that these graduates had acquired 21st-century skills in their respective degree programs. These results have corresponding implications for future research in confirming the most employable skills in secondary teaching. As recommended, classroom instruction might emphasize the development of these skills. Eventually, these become the competitive advantage and employability capitals of future graduates. Administering the licensure examination and the release of its results can be done within the first three months after graduation to lessen the cost of waiting.

Manuel caingcoy

Le 05 décembre 2012, les pratiques et expressions culturelles liées au balafon des communautés sénoufo du Mali, du Burkina Faso et de la Côte d’Ivoire ont été inscrites sur la Liste représentative du patrimoine culturel immatériel de l’humanité. Le tafal-djéguélé est une pratique et expression culturelle liée au balafon des Sénoufo de Côte d’Ivoire. Deux raisons principales fondent son usage : amener les laboureurs à la houe à se surpasser d’une part, et magnifier les valeurs des senambélé1 d’autre part, notamment celles en rapport avec le labour étant donné que le sénoufo est agriculteur par essence. Toutefois, en raison de certains changements sociaux, le tafal-djéguélése pratique de moins en moins. Cette situation prive le senanw d’aujourd’hui d’un cadre majeur d’enseignement et de diffusion de valeurs, et pose ainsi la question de leur transmission aux générations actuelles et futures. Cet article vise à démontrer comment la faible pratique du tafal-djéguélé empêche de nos jours la transmission de "valeurs- références" en pays sénoufo, mais aussi à proposer des pistes de solutions.

Assanvo

Over the years, pharmacy has developed from a simple floor stock system to a complex unit dose, I.V. additive, and clinical pharmacy program. This development would have never been possible without the support of the nursing, medical, and administrative staff. The support of obtained slowly by developing services that increase the pharmacist's credibility as a team member concerned with the pediatric and neonate patients. These services include a unit dose program, I.V. additive program, drug information services, and pharmacy medication program. One area in which pharmacist does not obtain a background from generalized training is the area of pediatric dosing. Pediatric pharmacists must learn in clinical practice the proper dosing of the pediatric patient and neonate patient. The dose must be checked periodically. In the premature or newborn infant, the pharmacist must consider the immature renal and hepatic function so that he/she does not overdose initially and then underdose as the infant grows and matures. Neonates are a special group of children, they are less than 30 days, and within this group preterm babies (that means less than 37 weeks). Determining the correct dose for drugs used to treat neonates is a critically vital factor. Prematurity affects kidney and liver function and the proper adjustment of drug doses is crucial [1]. The absence of drug level necessitates the adjustment of drug doses and the presence of qualified oriented dependable pharmacists. Drug doses are not numbers, or decimals used within the therapeutic range. Neonatal Intensive Care Unit (NICU) needs a system for the calculation and preparation of drugs [2].

Mediterranean journal of pharmacy and pharmaceutical sciences

COVID-19 is associate communicable disease caused by severe acute respiratory syndrome coronavirus. It's currently a virulent disease unfold moving several countries globally. The aim of this study is to assess the knowledge and practices of COVID-19 among general public at the selected setting, Chennai. The main objective was to assess the knowledge and practice on COVID-19, correlate the knowledge with practice on COVID-19, and associate the knowledge and practice on COVID-19 with the demographic variables among the public. A Quantitative non-experimental analysis style was used to assess the knowledge and practice of COVID-19. Sixty individuals were chosen through the non-probability convenience sampling technique. The findings of the analysis disclosed that the majority (40%) of the samples had a high level of knowledge and 43.3% of them had a good practice, 33.3% of them had a moderate level of knowledge and 30% of them had moderate practice, whereas 26.7% of them had a low level of knowledge and 26.7% of them had poor practice on COVID 19. Keywords:- COVID-19, Knowledge, Practice, Pandemic, General Public.

Elsi queen